ACMT Board Review Course Buzzwords Flashcards
Pneumoconiosis with hilar adenopathy, clinically and pathologically identical to sarcoidosis except no eye involvement, lymphocyte transformation test
Berylliosis
Porphyria, pemba yara, spongiform encephalopathy, outbreak in turkey in 1956
Hexachlorobenzene
Isolated thrombocytopenia, “bathtub refinished lung” sensitizing agent, largest recognized cause of occupational asthma
Toluene di-isocyanate
Hepatic angiosarcoma
Vinyl chloride
Pesticide operator with sterility, altered sex ratio in offspring
Dibromochloropropane (DBCP)
Da balls can’t produce
Phossy jaw
Yellow phosphorus
Brown lung, Monday morning tightness, byssanosis
Cotton
Hypertension, saturnine gout, renal failure, microcytic anemia
Adult lead poisoning
Silver solderers, proximal RTA, Itai-itai disease in jintsu river basin, acute lung injury, renal failure
Cadmium
Perforated nasal septum, lung cancer, painless ulcers, “blackjack disease”, type 4 hypersensitivity dermatitis
Chromium
Hairdresser with hearing loss renal failure, methemoglobinemia
Bromate
A cute psychosis with elevated chloride level
Bromide
Solvent, epoxide metabolite, degreasers flush, trigeminal neuralgia
Trichloroethylene
Viscous rayon, increase rate of atherosclerosis, disulfiram and metam sodium metabolites, basal ganglia toxin, associated with spontaneous abortions, decreased spermatogenesis, craniofacial abnormalities, optic nerve and retinal degeneration
Carbon disulfide
The percentage of sick people who are identified as having the condition
Or
The likelihood of a test being positive if the condition is present
Sensitivity
A result of 100% means that the test recognizes all healthy people as healthy
Or
The likelihood of the unaffected individuals correcting having a negative test
Specificity
Solvent, acute can depression, arrhythmias, aml, Hodgkin’s lymphoma, paroxysmal nocturnal hemoglobinuria
Benzene
Wastewater treatment worker with sensory and motor distal axonal neuropathy , also has blue discoloration of hands and feet, desquamation and pulmonary irritation
Acrylamide
Ginger Jake, NTE inhibitor, sensory motor neuropathy, -1960 Morocco disaster
Triorthocresylphosphate
Mina mats bay
Methyl Mercury
Bhopal diasaster
Methyl isocyanate
Lung cancer, beer drinker with cardiomyopathy, classic tetrad
- Goiter
- Cardiomyopathy
- Metabolic acidosis
- Polycythemia
Inhibits oxidation of a-KG 59 succinyl-Co-A and pyruvate to acetyl-CoA
Cobalt
Pulmonary disease-anemia syndrome
Strong respiratory sensitizer
Trimellitic anhydride
Uranium mining, lung cancer
Radon
Firefighter with delayed pulmonary edema and smell of freshly mowed hay
Phosgene
Pest control operator with fishy odor, respiratory distress, refractory hypotension, delayed pulmonary edema
Phosphine AKA phosfish
Sewage worker with rapid collapse, mucous membranes irritation, blackened jewelry, sodium nitrite antidote
Hydrogen sulfide
Endoscopy technician with mucous membrane irritation, pulmonary edema, leukemia, sweet odor, N/V
Ethylene oxide
Epping jaundice
Methylenedianiline
Aromatic solvent, acute CNS depression, basal ganglia toxin, hypokalemia, pneumonitis, RTA/renal failure, myopathy, leukoencephalopathy
Toluene
Fungicide with pungent odor, skin and respiratory sensitizer, photoallergic dermatitis
Captafol
1937 sulfanilamide poisoning
Diethylene glycol
Neonatal gasping syndrome
Benzyl alcohol
1986 lake nyos disaster
Carbon dioxide
Eosinophilia myalgia syndrome
L-tryptophan
Koremlu poisoning
Thallium
Explosives/munitions production, spandex fibers, causes severe GI distress and vomits that smells like bitter almonds, retro ulnar and optic neuropathy, methemoglobinemia, hepatitis, aplastic anemia, yellowing of skin hair and dyes
1,3 dinitrobenzene
Oily liquid used in explosives and diisocyanate production, possible weight loss product, uncoupler, optic neuropathy, turns skin yellow
Dinitrotoluene
Sweet smelling irritant gas, insect fumigant and heat stabilizer for plastic production, delayed pulmonary toxicity
Epichlorohydrin
Textile finishing agent and used in the synthesis of malathion, vapors result in corneal edema, photophobia, and diplopia, chronic use associated with occupational asthma, hemolytic anemia and pulmonary hemorrhage
Maleic anhydride
Used as an odors t for natural gases, rotten cabbage odor, methemoglobin and hemolytic anemia
Mercaptans
Abdominal pain, hemolytic anemia, Paris green, hematuria, bronze skin
Arsine
Metals that produce non-fibrogenic benign pneumoconiosis (5)
- Tin (stannosis)
- Barium (baritosis)
- Iron (siderosis)
- Calcium (chalitosis)
- Melybdenun
Vineyard sprayers lung - interstitial pulmonary fibrosis, histiocytic grabulomas, adenocarcinoma
Copper sulfate - Bordeaux solution
Hard metal pneumoconiosis, pulmonary eosinophilia portends poor prognosis
Tungsten-carbide
Diamond polishers lung
Cobalt
Patient on dialysis who develops somnolence, peri oral numbness, abdominal pain and hyperamylasemia
Manganese sulfate
Worker with osteosclerosis with accompanying nerve root compression. Plain film X-ray reveals ligament calcification and lesions resembling osteoblasts metastasis
Fluorisis cryolite (NaAlFl)
Acroosteolysis (bone resorption at distal phalanx)
Vinyl chloride
Most common medication associated with hypersensitivity pneomonitis
Nitrofurantoin
Middle aged adult with chronic seizure disorder with X-rays demonstrating hilar lymphadenopathy. Biopsy reveals drug-induced lymphoid hyperplasia.
Phenytoin
Elderly male with hepatic angiocarcinoma and pneumococcal sepsisz abdominal X-ray reveals multiplied opacities in the liver and spleen
Thorotrast (thorium dioxide)
Zenobiotic induced aplastic anemia is most often associated with destruction of these progenitor cells
CD34+ progenitor cells
Lymphoma in a Dutch flower bulb worker using a nematode fumigant (also seen in fireman)
Dichloropropene (telon)
Cola colored infant with MRCP, abnormal skull calcification and hypo plastic nails
PCBS
PEPSI COLORED BABIES
Metabolite of disulfiram and used in the treatment of nickel carbonyl and platinoid poisoning
Diethylsithiocarbamate (DDC)
4 year old in an antineoplasric drug develops fever, SIADH, necrotic myocardial infarction, and loss of deep Tendon reflexes
Vincristine
Antineoplastic producing hilar adenopathy
MTX
Antineoplastic producing nodular bronchiolitis ollbliterans
Bleomycin
Antineoplastic associated with perforation of the GI tract
Paclitaxol
Antineoplastic associated with hemolytic uremic syndrome
Mitomycin
Metal that is radiolucent on plain film X-ray
Copper
Metal causing parasthesias (pins and needles), ataxia, dysarthria, constructed visual fields, deafness
Methyl Mercury
Pink disease - Mercury teething powders such as calomel
Mercury calomel (HgCl)
Hopewell epidemic, “Kepone shakes”, Chessapeake Bay contamination
Chlordecone
Stalinon poisoning, vomiting, transitory paralysis, photophobia, white matter edema
Triethyltin
Golfer with disulfiram reaction at the 18th hole
Thiuram Herbicide
Welder with early Parkinson’s Disease
Manganese
Paraket dies while family is cooking in the kitchen
Polymer fume fever
Welder dies after ingesting soldering flux
Zinc chloride
Black henna, black hair dye, angioedema, renal failure, methemoglobinemia, leukemia/bladder cancer
Para-phenylenediamides
Fumigant worker, peanut poisoning, fish odor
Zinc phosphide
Young male chimney sweeper with testicular cancer
Polyaromatic hydrocarbons
Middle aged male stripping paint that develops angina from delayed carbon monoxide poisoning
methylene chloride
Galvanized metal welder, “Monday morning fever”, “brass foundry workers argue”
Zinc oxide (metal fume fever)
Mill worker with allergic contact dermatitis, and respiratory sensitization (occupational asthma)
Plicatic acid (western red cedar)
Farmer’s lung
Thermophilic actinomycetes
irritant gas, warning agent in methylene chloride, component of papite (tear gas), cyclophosphamide metabolite
Acrolein
Urine metabolite of acrylamide used for testing worker exposure
carboxyethyl-cystine
Primary ingrediant in skin cement, skin sensitizer, elevated urine mercapturic acid, pediatric burns
methyl methacrylate
Spain 1981: rapeseed oil contaminated with aniline, diffuse pulmonary infiltrates on x-ray, methemoglobinemia
aniline
Airbag inflation, herbicide, cytochroma alpha-a3 inhibitor
sodium azide
Fumigant, fire extinguisher, lower extremity axonopathy, intoxication resemble’s Wernicke’s encephalopathy, inferior colliculi lesions, NAC may worsen syndrome
Methyl bromide
Irritant gas with gasoline-like odor, may cause hypotension and bradycardia with inhalation, associated with lymphohematopoetic cancer
1, 3, butadiene
Current pesticide/herbicide but once a mouthwash and toothpaste, methemoglobinemia and Gi distress 3-6 hours after ingestion
sodium chlorate
Hyperthyroid medication that was linked to aplastic anemia, now ground water contaminant
Perchlorates
Tar smarts, pitch warts and squamous cell carcinoma, chronic melanosis, UV phototoxicity, strong carcinogen of lung, bladder, skin, scrotal, oral, stomach
Coal tar products
Ammonia-like odor, rocket fuel and water treatment agent: toxicity tetrad: SLE (skin sensitizer), methemoglobinemia, seizures, hepatitis
Hydrazines
Paint remover and solvent with fishy or ammonia smell that cause severe hepatitis with jaundice and eventual liver failure
Dimethylacetamide
Solvent used in pharmaceutical industry, acrylic fiber production and recovery of CO2 in gasses that may result in skin irritation, severe hepatotoxicity, and disulfiram reactions
N,N-dimethylformamide