ACMT Board Review Course Buzzwords Flashcards

1
Q

Pneumoconiosis with hilar adenopathy, clinically and pathologically identical to sarcoidosis except no eye involvement, lymphocyte transformation test

A

Berylliosis

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2
Q

Porphyria, pemba yara, spongiform encephalopathy, outbreak in turkey in 1956

A

Hexachlorobenzene

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3
Q

Isolated thrombocytopenia, “bathtub refinished lung” sensitizing agent, largest recognized cause of occupational asthma

A

Toluene di-isocyanate

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4
Q

Hepatic angiosarcoma

A

Vinyl chloride

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5
Q

Pesticide operator with sterility, altered sex ratio in offspring

A

Dibromochloropropane (DBCP)

Da balls can’t produce

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6
Q

Phossy jaw

A

Yellow phosphorus

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7
Q

Brown lung, Monday morning tightness, byssanosis

A

Cotton

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8
Q

Hypertension, saturnine gout, renal failure, microcytic anemia

A

Adult lead poisoning

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9
Q

Silver solderers, proximal RTA, Itai-itai disease in jintsu river basin, acute lung injury, renal failure

A

Cadmium

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10
Q

Perforated nasal septum, lung cancer, painless ulcers, “blackjack disease”, type 4 hypersensitivity dermatitis

A

Chromium

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11
Q

Hairdresser with hearing loss renal failure, methemoglobinemia

A

Bromate

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12
Q

A cute psychosis with elevated chloride level

A

Bromide

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13
Q

Solvent, epoxide metabolite, degreasers flush, trigeminal neuralgia

A

Trichloroethylene

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14
Q

Viscous rayon, increase rate of atherosclerosis, disulfiram and metam sodium metabolites, basal ganglia toxin, associated with spontaneous abortions, decreased spermatogenesis, craniofacial abnormalities, optic nerve and retinal degeneration

A

Carbon disulfide

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15
Q

The percentage of sick people who are identified as having the condition

Or

The likelihood of a test being positive if the condition is present

A

Sensitivity

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16
Q

A result of 100% means that the test recognizes all healthy people as healthy

Or

The likelihood of the unaffected individuals correcting having a negative test

A

Specificity

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17
Q

Solvent, acute can depression, arrhythmias, aml, Hodgkin’s lymphoma, paroxysmal nocturnal hemoglobinuria

A

Benzene

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18
Q

Wastewater treatment worker with sensory and motor distal axonal neuropathy , also has blue discoloration of hands and feet, desquamation and pulmonary irritation

A

Acrylamide

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19
Q

Ginger Jake, NTE inhibitor, sensory motor neuropathy, -1960 Morocco disaster

A

Triorthocresylphosphate

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20
Q

Mina mats bay

A

Methyl Mercury

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21
Q

Bhopal diasaster

A

Methyl isocyanate

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22
Q

Lung cancer, beer drinker with cardiomyopathy, classic tetrad

  1. Goiter
  2. Cardiomyopathy
  3. Metabolic acidosis
  4. Polycythemia

Inhibits oxidation of a-KG 59 succinyl-Co-A and pyruvate to acetyl-CoA

A

Cobalt

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23
Q

Pulmonary disease-anemia syndrome

Strong respiratory sensitizer

A

Trimellitic anhydride

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24
Q

Uranium mining, lung cancer

A

Radon

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25
Q

Firefighter with delayed pulmonary edema and smell of freshly mowed hay

A

Phosgene

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26
Q

Pest control operator with fishy odor, respiratory distress, refractory hypotension, delayed pulmonary edema

A

Phosphine AKA phosfish

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27
Q

Sewage worker with rapid collapse, mucous membranes irritation, blackened jewelry, sodium nitrite antidote

A

Hydrogen sulfide

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28
Q

Endoscopy technician with mucous membrane irritation, pulmonary edema, leukemia, sweet odor, N/V

A

Ethylene oxide

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29
Q

Epping jaundice

A

Methylenedianiline

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30
Q

Aromatic solvent, acute CNS depression, basal ganglia toxin, hypokalemia, pneumonitis, RTA/renal failure, myopathy, leukoencephalopathy

A

Toluene

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31
Q

Fungicide with pungent odor, skin and respiratory sensitizer, photoallergic dermatitis

A

Captafol

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32
Q

1937 sulfanilamide poisoning

A

Diethylene glycol

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33
Q

Neonatal gasping syndrome

A

Benzyl alcohol

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34
Q

1986 lake nyos disaster

A

Carbon dioxide

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35
Q

Eosinophilia myalgia syndrome

A

L-tryptophan

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36
Q

Koremlu poisoning

A

Thallium

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37
Q

Explosives/munitions production, spandex fibers, causes severe GI distress and vomits that smells like bitter almonds, retro ulnar and optic neuropathy, methemoglobinemia, hepatitis, aplastic anemia, yellowing of skin hair and dyes

A

1,3 dinitrobenzene

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38
Q

Oily liquid used in explosives and diisocyanate production, possible weight loss product, uncoupler, optic neuropathy, turns skin yellow

A

Dinitrotoluene

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39
Q

Sweet smelling irritant gas, insect fumigant and heat stabilizer for plastic production, delayed pulmonary toxicity

A

Epichlorohydrin

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40
Q

Textile finishing agent and used in the synthesis of malathion, vapors result in corneal edema, photophobia, and diplopia, chronic use associated with occupational asthma, hemolytic anemia and pulmonary hemorrhage

A

Maleic anhydride

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41
Q

Used as an odors t for natural gases, rotten cabbage odor, methemoglobin and hemolytic anemia

A

Mercaptans

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42
Q

Abdominal pain, hemolytic anemia, Paris green, hematuria, bronze skin

A

Arsine

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43
Q

Metals that produce non-fibrogenic benign pneumoconiosis (5)

A
  1. Tin (stannosis)
  2. Barium (baritosis)
  3. Iron (siderosis)
  4. Calcium (chalitosis)
  5. Melybdenun
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44
Q

Vineyard sprayers lung - interstitial pulmonary fibrosis, histiocytic grabulomas, adenocarcinoma

A

Copper sulfate - Bordeaux solution

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45
Q

Hard metal pneumoconiosis, pulmonary eosinophilia portends poor prognosis

A

Tungsten-carbide

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46
Q

Diamond polishers lung

A

Cobalt

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47
Q

Patient on dialysis who develops somnolence, peri oral numbness, abdominal pain and hyperamylasemia

A

Manganese sulfate

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48
Q

Worker with osteosclerosis with accompanying nerve root compression. Plain film X-ray reveals ligament calcification and lesions resembling osteoblasts metastasis

A

Fluorisis cryolite (NaAlFl)

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49
Q

Acroosteolysis (bone resorption at distal phalanx)

A

Vinyl chloride

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50
Q

Most common medication associated with hypersensitivity pneomonitis

A

Nitrofurantoin

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51
Q

Middle aged adult with chronic seizure disorder with X-rays demonstrating hilar lymphadenopathy. Biopsy reveals drug-induced lymphoid hyperplasia.

A

Phenytoin

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52
Q

Elderly male with hepatic angiocarcinoma and pneumococcal sepsisz abdominal X-ray reveals multiplied opacities in the liver and spleen

A

Thorotrast (thorium dioxide)

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53
Q

Zenobiotic induced aplastic anemia is most often associated with destruction of these progenitor cells

A

CD34+ progenitor cells

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54
Q

Lymphoma in a Dutch flower bulb worker using a nematode fumigant (also seen in fireman)

A

Dichloropropene (telon)

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55
Q

Cola colored infant with MRCP, abnormal skull calcification and hypo plastic nails

A

PCBS

PEPSI COLORED BABIES

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56
Q

Metabolite of disulfiram and used in the treatment of nickel carbonyl and platinoid poisoning

A

Diethylsithiocarbamate (DDC)

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57
Q

4 year old in an antineoplasric drug develops fever, SIADH, necrotic myocardial infarction, and loss of deep Tendon reflexes

A

Vincristine

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58
Q

Antineoplastic producing hilar adenopathy

A

MTX

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59
Q

Antineoplastic producing nodular bronchiolitis ollbliterans

A

Bleomycin

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60
Q

Antineoplastic associated with perforation of the GI tract

A

Paclitaxol

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61
Q

Antineoplastic associated with hemolytic uremic syndrome

A

Mitomycin

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62
Q

Metal that is radiolucent on plain film X-ray

A

Copper

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63
Q

Metal causing parasthesias (pins and needles), ataxia, dysarthria, constructed visual fields, deafness

A

Methyl Mercury

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64
Q

Pink disease - Mercury teething powders such as calomel

A

Mercury calomel (HgCl)

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65
Q

Hopewell epidemic, “Kepone shakes”, Chessapeake Bay contamination

A

Chlordecone

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66
Q

Stalinon poisoning, vomiting, transitory paralysis, photophobia, white matter edema

A

Triethyltin

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67
Q

Golfer with disulfiram reaction at the 18th hole

A

Thiuram Herbicide

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68
Q

Welder with early Parkinson’s Disease

A

Manganese

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69
Q

Paraket dies while family is cooking in the kitchen

A

Polymer fume fever

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70
Q

Welder dies after ingesting soldering flux

A

Zinc chloride

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71
Q

Black henna, black hair dye, angioedema, renal failure, methemoglobinemia, leukemia/bladder cancer

A

Para-phenylenediamides

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72
Q

Fumigant worker, peanut poisoning, fish odor

A

Zinc phosphide

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73
Q

Young male chimney sweeper with testicular cancer

A

Polyaromatic hydrocarbons

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74
Q

Middle aged male stripping paint that develops angina from delayed carbon monoxide poisoning

A

methylene chloride

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75
Q

Galvanized metal welder, “Monday morning fever”, “brass foundry workers argue”

A

Zinc oxide (metal fume fever)

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76
Q

Mill worker with allergic contact dermatitis, and respiratory sensitization (occupational asthma)

A

Plicatic acid (western red cedar)

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77
Q

Farmer’s lung

A

Thermophilic actinomycetes

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78
Q

irritant gas, warning agent in methylene chloride, component of papite (tear gas), cyclophosphamide metabolite

A

Acrolein

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79
Q

Urine metabolite of acrylamide used for testing worker exposure

A

carboxyethyl-cystine

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80
Q

Primary ingrediant in skin cement, skin sensitizer, elevated urine mercapturic acid, pediatric burns

A

methyl methacrylate

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81
Q

Spain 1981: rapeseed oil contaminated with aniline, diffuse pulmonary infiltrates on x-ray, methemoglobinemia

A

aniline

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82
Q

Airbag inflation, herbicide, cytochroma alpha-a3 inhibitor

A

sodium azide

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83
Q

Fumigant, fire extinguisher, lower extremity axonopathy, intoxication resemble’s Wernicke’s encephalopathy, inferior colliculi lesions, NAC may worsen syndrome

A

Methyl bromide

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84
Q

Irritant gas with gasoline-like odor, may cause hypotension and bradycardia with inhalation, associated with lymphohematopoetic cancer

A

1, 3, butadiene

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85
Q

Current pesticide/herbicide but once a mouthwash and toothpaste, methemoglobinemia and Gi distress 3-6 hours after ingestion

A

sodium chlorate

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86
Q

Hyperthyroid medication that was linked to aplastic anemia, now ground water contaminant

A

Perchlorates

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87
Q

Tar smarts, pitch warts and squamous cell carcinoma, chronic melanosis, UV phototoxicity, strong carcinogen of lung, bladder, skin, scrotal, oral, stomach

A

Coal tar products

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88
Q

Ammonia-like odor, rocket fuel and water treatment agent: toxicity tetrad: SLE (skin sensitizer), methemoglobinemia, seizures, hepatitis

A

Hydrazines

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89
Q

Paint remover and solvent with fishy or ammonia smell that cause severe hepatitis with jaundice and eventual liver failure

A

Dimethylacetamide

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90
Q

Solvent used in pharmaceutical industry, acrylic fiber production and recovery of CO2 in gasses that may result in skin irritation, severe hepatotoxicity, and disulfiram reactions

A

N,N-dimethylformamide

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91
Q

Riboflavin inhibition, painful peripheral neuropathy, neuropathy spares CN 1, 5, 8, slope is with sparing of the Axila facial hair and inner 1/3 of eyebrow, reverse sleep cycle

A

Thallium

92
Q

Benzene monitoring

A

Total urine phenol

93
Q

Toluene monitoring

A

Urine hippuric acid

94
Q

Styrene monitoring

A

Urine mandelic and phenylglyoxylic acid

95
Q

Lead monitoring

A

Blood ZPP/FEP

96
Q

Methyl Mercury monitoring

A

Blood Mercury

97
Q

Inorganic Mercury monitoring

A

Urine Mercury

98
Q

Polyaromatic HC monitoring

A

Urine 1-hydroxypyrene

99
Q

Pily liquor in cold sterilization, sensitizer and occupational asthma

A

Glutaraldehyde

100
Q

Used in plastics and rubber, dental fillings and styrofoam. Causes flu-like symptoms and drunkenness activity, peripheral neuropathy and hearing loss chronically

A

Styrene - styrene syndrome

101
Q

Chemical associated with highest incidence of lung cancer in the world

A

Polyaromatic HC

102
Q

Dentist with vitamin b-12 like deficiency, bone marrow suppression, and pernicious anemia. Histochemistry reveals inactive cobalt and inhibition of methionine synthetase.

A

Nitrous oxide

103
Q

Person exposed to a cloud of “red smoke” with delayed pulmonary edema and chemical burns with characteristic yellow discoloration

A

Nitric acid

104
Q

Pyrophoric material causing severe thermal and chemical burns (submerge in CuSO4) and exposure may lead to hepatotoxicity and hypocalcemia and increase QT interval

A

White phosphorus

105
Q

“Rush” fire in San Fran in 1983 leading to a number of firefighters with methemoglobinemia

A

Isobutyl nitrate

106
Q

1978 Jonestown mass suicide

A

KCN

107
Q

Only organic phosphorus pesticide that possesses a significant vapor hazard (high vapor pressure)

A

Dichlorvos (also very hydrophilic - amenable to HD maybe)

108
Q

Patient presenting after herbicide ingestion with myotonia, myoclonus, hematuria/rhabdo, and cardiac disturbances

A

Chlorphenoxy herbicide

109
Q

Fetal syndrome - 10-30%, 25% risk of spontaneous abortion, microcephaly/hydrocephaly, conventional heard disorders, microtia, cleft lip-palate

A

Fetal isotretinoin

110
Q

Microcephaly, development delay, telecsnthus, short nose and flat nasal bridge, anteverted nares, long shallow fitrum, thin upper lip, nail displasia

A

Fetal hydantoin

111
Q

Microcephaly, small palpebral fissure length, thin upper lip, smooth Phil trim, flattened cheeks and short nose. Risk of brain injury increases as eyes get smaller, philtrum get flatter, and lip gets thinner

A

Fetal alcohol

112
Q

Small nose and markedly depressed nasal bridge, brachydactyl, hypoplasia of all distal phalanges, severe shortening of lower extremities, epiphyseal stippling of the sacrum, spine, proximal humeri, and femurs

A

Fetal warfarin

113
Q

Parrot fish and tidal xanthid crabs

Inhibits Na/K ATPase, N/V/D, parasthesias, hypocalcemic tenany, CV collapse (second most potent toxin on earth)

A

Palytoxin

114
Q

Paralytic shellfish poisoning, Na channel blocker, oysters/red tide, N/V, parasthesias, throat pain, descending paralysis

A

Saxitoxin

115
Q

Neurotoxin shellfish poisoning, sodium channel opener, parasthesias, temperature reversal, N/V/D uncommon, tide aerosolized toxin causes conjunctivitis, rhinitis, bronchitis

A

Brevetoxin

116
Q

Diarrhetic shellfish poisoning, inhibits protein phosphates disrupting cell metabolism, benign gastric tumors, N/V/D predominate

A

Okadaic acid

117
Q

Amnestic shellfish poisoning, CNS glutamate receptor stimulation causing Na channel up regulation and Na/Ca influx g neuronal cell dementia, N/V/D, headaches, ataxia, seizures, associated with eating blue muscles

A

Domoic acid

118
Q

Na and Ava channel opening, metallic taste, parasthesias, glove and stocking numbness, hot/cold reversal, sensation of loose teeth, symptoms worse with alcohol

A

Ciguatoxin

119
Q

Bacteria-catalyzed decarboxylation of decomposition finfish muscle, sunburn like rash, urticaria, bronchospasm

A

Scombroid (histamine poisoning)

120
Q

Sodium channel blocker, perioral parasthesias, numbensss tremor ataxia dysarthria dysphasia respiratory paralysis death 5th most potent toxin

A

Tetrodotoxin

121
Q

Japanese vinyl sandal maker with peripheral sensorimotor neuropathy. Nerve biopsy reveals Axonal swelling.

A

N-hexane

122
Q

Cicuta spp. Most fatal plant species in North America - 30-70% fatality rate

A

Water hemlock -

123
Q

The only form of poisoning caused by bacterial contamination

A

Scombroid (decarboxylation of histadine in fish muscle to histamine)

124
Q

St Anthony’s fire, ergotism

A

Claviceps purpurea

125
Q

Structural similarity to the herbicide endothall, also known as Spanish fly, produced by the blister beetle

A

Cantharidin

126
Q

Profound hypoglycemia, hepatitis with hyperbilirubinemia, acid emus and acidurea without Ketosis

A

Akee (hypoglycin)

127
Q

The maximum concentration of a chemical to which a worker may be exposed continuously for up to 15 minutes without danger to health or work efficiency and safety

A

Stel - short term exposure limit

128
Q

Sulfonylurea known to cause SIADH and disulfiram reactions

A

Chlorpropamide

129
Q

Side chain of cephalosporins linked to disulfiram reactions

A

NMTT - n-methtltetrathiol

130
Q

Antidysrhthmic with antimuscarnic properties and causes hypoglycemia

A

Disopyramide

131
Q

Intoxicants that produce metaphyseal bands on plain fil x-ray

A

Lead
Yellow phosphorus
Bismuth
Hyper vitaminosis D

132
Q

5 most common medications linked to lupus-like syndrome

A
CHIMP
chlorpropamide
Hydralazine
INH
Methyldopa
Procainamide
133
Q

Idiopathic intracranial hypertension (pseudo tumor cerebri)

A

Vitamin A

134
Q

Chinese herbal remedy with bufadenalide cardiac steroid

A

Chan Su

135
Q

Plant that is a cyp3A4 inducer

A

At John wort - hypericum perforatum

136
Q

Pulegone -> methofuran -> hepatitis

A

Pennyroyal oil (mentha pelugium)

137
Q

Aspiration pneumonitis, CNS depression, patients urine smells like violets

A

Terpentine (pine oil)

138
Q

Essential oil, CNS depression, mild hepatitis, hemorrhagic pulmonary edema

A

Oil of cloves - eugenol - Eugenia aromatica

139
Q

Most common cause of medication-induced contact dermatitis

A

Neomycin

140
Q

Endocarditis and mistrial vale fibrosis, pulmonary hypertension

A

Fenfluramine

141
Q

Disinfectant associated with neonatal vacuoles encephalopathy and cerebral edema

A

Hexachloraphene

142
Q

Disinfectant ingestion causingetahilic acidemia due to a decreased renal clearance of H (patient has normal lactate)

A

Providine iodine

143
Q

Disinfectant, hypopigmented skin, TD-like syndrome, bradycardia, hypotension, PEG decontamination

A

Phenol

144
Q

Rose eye discoloration of eyelids, conjunctivitis, refractory hypotension, reddish discoloration of viscera post-Mortem

A

Acute selenium toxicity (selenious acid)

145
Q

Peanut worker who develops liver cancer (hepatoma)

A

Alfatoxin

146
Q

Bio marker for benzene exposure

A

Urine phenol

147
Q

HIV medication associated with fatal hypersensitivity

A

Abacavir

148
Q

Two P450s associated with development of cancer

A

1A2, 2E1

149
Q

Enzyme linked to aromatic anticonvulsant hypersensitivity syndrome

A

Epoxide hydrolase

150
Q

The only medication induced seizure that will likely respond to phenytoin

A

Aminopyridine

151
Q

The only local anesthetic that causes vasoconstriction

A

Cocaine

152
Q

Most cardio toxic amide local anesthetic (may cause cardio toxicity before CNS toxicity

A

Bupivacaine

153
Q

Most extensively metabolized anesthetic, hepatitis, malignant hyperthermia, acute lung injury from abuse (PO/IV)

A

Halothane

154
Q

The only IARC Group 4 drug - probably not carcinogenic to humans

A

Caprolactam

155
Q

Patient with ventricular ectopy, blindness, NV, dishonored is tinnitus after drinking tonic water with Cinchona succirubra extract

A

Quinine

156
Q

Biventricular tachycardia

A

Digoxin, aconitine, halogenated hydrocarbons

157
Q

Patient with an aortic dissection and renal failure that develops altered mental status, seizures, and no metabolic acidosis

A

Thiocyanate toxicity

158
Q

Opioid linked to serotonin syndrome, seizures, MPTP, and may not result in milieus in overdose

A

Meperidine

159
Q

NSAID linked to aplastic anemia

A

Phenylbutazone

160
Q

Patient with hiv with sulfa allergy who develops hemolysis and methemoglobinemia

A

Dapsone

161
Q

Patient undergoing elective endoscopy that develops methemoglobinemia during pre-op

A

Benzocaine

162
Q

Free radical induced cardiomyopathy with irreversible heart failure

A

Doxorubicin

163
Q

Alkylation agent causing hemmhoragic cystitis, MESNA antidote

A

Cyclophosphamide

164
Q

Allylating agent causing pulmonary fibrosis and skin hyperpigmentation

A

Busulfan

165
Q

6 intoxicants for which urine alkalinizarion enhances drug elimination

A
Salicylate
Phenobarbital
chlorphenoxy herbicides 
Methotrexate
Chlorpropamide
Fluoride
166
Q

Scleritis and uveitis in a patient being treated for hypercalcemia

A

Bisphosphanates

167
Q

Peliosis hepatitis

A

Alkalated anabolic steroids

168
Q

Black widow spider
Painful bite
Calcium channel opener
Causes release of NE ACH

A

Latrodectus mactans

169
Q
Brown recluse
Painless bite
sphingomyelinase D
Hyaluronidase
Local wound (red white blue)
A

Loxosceles reclusa

170
Q

Hobo spider
Painless bite
Local ulcer

A

Tegenaria agrestis

171
Q

Box jellyfish
Most lethal cnideria
Rapid death in minutes
Acetic acid/Antivenom

A

Chironex fleckeri

172
Q

Irukanji syndrome
Hypertension
Back spasms

A

Carukia barnesi

173
Q

Portuguese man of war
Painful linear welts
Acetic acid

A

Physalia physallis

174
Q

Crown of thorns
Pain, paralysis
Hot water immersion

A

Acanthaster planc

175
Q

Lion fish
Pain possible blisters
Hot water immersion

A

Pterosis species

176
Q

Stonefish
Cytotoxic, hemolytic, myotoxic
Severe pain, hypotension, hemolysis
Hot water, antivenin

A

Synanceja verrucosa

S. Horrida

177
Q

Stingray
Local pain
Vibrio infections
Hot water, antibiotics

A

Dasyatis species

178
Q

Funnel web spider
Massive release of ACH, NE, EPI
RAbbit igg antivenin
Death historically in peds under 4

A

Atrax robustus

179
Q

Fire ant
Glucosaminidase, piperidines
Wheals, clear vesicles
Local care

A

Solenopsis invecta

180
Q

Bark scorpion
Sodium channel opener
Pain, parenthesis, palsies

A

Centruroidea exilicauda

181
Q

Colorado river toad
Bufadienolide cardiac steroid
Bufotenin tryptamines
Chan su herbal

A

Bufo alvarius

182
Q

Body builder presenting with tachycardia, wide pulse pressure, hypokalemia

A

Clenbuterol

183
Q

silo filers disease

A

Nitric oxides (No, No2)

184
Q

Basal ganglia toxins

A
CO
CArbon disulfide
manganese
MTPP+
Methanol
185
Q

Remediation level for home radon

A

11 pc/L

186
Q

Theee agents associated with perinatal death

A

ACE inhibitors
Cigarette smoking
Lead

187
Q

Most common hydrocarbon used in dry cleaning

A

PERC

perchloroethylene

188
Q

Cement worker with contact dermatitis

A

Chromium 6

189
Q

OSHA PEL for benzene

A

1 ppm

190
Q

OSHA PEL for CO

A

50 ppm

191
Q

Azo dye and rubber manufacturing, HCN lab detection agent, methemoglobinemia, associated with bladder cancer (IARC 1)

A

Benzidine

192
Q

Patient etching glass and wheel cleaning with delayed pain out of proportion to exam, hypocalcemia, hyperkalemia

A

HF

193
Q

Vitamin B6 antidote for 4 toxins

A

INH
Gyromitra esculenta
Hydrazines
Ethylene glycol

194
Q

The factor by which exposure is reduced by use of a respirator

A

Protection factor

Ambient/protection factor = exposure

195
Q

Study design comparing an exposed group to an unexposed group either retro-or prospectively with results expressed as relative risk

A

Cohort study

196
Q

Study design comparing an exposed group to an unexposed group at one point in time. Provides prevalence data, results expressed as relative risk

A

Cross-sectional study

197
Q

Study design comparing individuals with a specific condition to those do not have the condition and compare exposures or risk factors. Results expressed as odds ratio.

A

Case control study

198
Q

Federal agency responsible for conducting research and making recommendations for the prevention of work related injury and illness - has no legal authority

A

NIOSH

199
Q

The main federal agency charged with enforcement of safety and health legislation

A

OSHA

200
Q

Enacted by Congress in 1980 and created a tax on the chemical and petroleum industries and provided broad federal authority to respond directly to releases or threatened releases of hazardous substances that may endanger public health or the environment

A

CERCLA

comprehensive environmental response, compensation, and liability act

201
Q

Federal public agency charged with the responsibility of evaluating the human health effects of exposure to hazardous substances

A

ATSDR

202
Q

Characteristics of substances partitioning into breast milk

A

low molecular weight
Non-polar
Low protein binding

203
Q

Risk factors for quinolone induced tendinopathy

A
Age over 60
Non-obese
Steroid use 
Female
Renal failure
Diabetes
204
Q

Hepatic zone where 2E1 is primarily present and active

A

Zone 3

Centeilobular necrosis

205
Q

Primary toxicity associated with methoxyflurane

A

Nephrotoxicity

206
Q

Tetrodotoxin MOA

A

NA channel blocker

207
Q

Saxitoxin MOA

A

Blocks Na channel

208
Q

Brevetoxin MOA

A

stimulates Na Channels

209
Q

Domoic acid MOA

A

glutamate agonist, analog of glutamic and kainic acid

210
Q

Okadoic acid MOA

A

Phosphates a1 and a1 inhibitor

211
Q

Ciguatoxin MOA

A

Lowers threshold for opening Na channels

212
Q

Toxins associated with peripheral neuropathy (5)

A
Acrylamide
Methyl bromide
Carbon disulfide
Styrene
Trichloroethylene
213
Q

Occupational intoxicants associated with asthma (5)

A
Maleic acid
Trimellitic anhydride
Ethtlenediamine
Toluene diisocyanate (#1)
Diethtlhexyl phthalate
214
Q

Rodenticide producing nausea vomiting bradycardia hyperkalemia

A

Red squill (digoxin)

215
Q

Rodenticide producing CNS excitation, irritability, seizures, coma, ventricular dysrhythmias

A

Tetramine

216
Q

Rodenticide producing orophyngeal and skin burns, smoking coming and stools, garlic odor, GI and hepatic injury

A

Phosphorus

217
Q

Rodenticide producing tremors, myoclonus, depressed mental status

A

Bromethalin

218
Q

Toxin used in hospital laundry. Toxicity resulted in 9 neonates ill, 2 deaths. Presented with fever sweating renal failure and acidosis, this agent was also used in various ways including in treating wood to function as preservative, also uncouples oxidative phosphorylation

A

Pentachlorophenol

219
Q

Chemicals associated with causing chloracne

A

Chlorinated aromatic hydrocarbons

220
Q

Hairdresser hand dermatitis

A

P-phenylenediamine

221
Q

International treaty completed in 1987 by 24 nations to control the depletion of the ozone layer. Targeted the decrease of CFCs and halons used in fire extinguishers - halon 1211 and 1301

A

Montreal protocol

222
Q

Shoemakers polyneuropathy

A

N-hexane… same as with methy-n-buyl ketone. All metabolized to 2,5-butanedione

223
Q

Toluene toxicity (4 major)

A

Distal RTA
MEtabolic acidosis
Hypokalemia and associated symptoms
Leukoencephalopathy

224
Q

The only hydrocarbon exposures associated with a chance in CV mortality

A

Carbon disulfide
Associated with accelerated atherosclerotic CAD
ALso peripheral neuropathy

225
Q

Cement eczema

A

Chromium 6+

Type 4 hypersensitivity reaction

226
Q

Wolf-chaikoff effect

A

Chronic iodine exposure leads to decreased hormone productions the inhibition of organic binding of iodide in the thyroid gland by excess iodide leading to decreased thyroid synthesis