ACLS Drugs Flashcards

1
Q

Drugs given by peripheral I.V. route take how long to reach central cirulation?

A

1 to 2 min.

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2
Q

If any drug is given peripherally I.V., administer it as follows:

A
  1. Give as bolus inj. unless otherwise specified
  2. Follow with 20mL flush
  3. Elevate extremity for 10-20 sec
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3
Q

Vasopressors

What drugs are used during cardiac arrest?

A

Epinephrine (1:10,000)

or

Vasopressin

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4
Q

Vasopressors

Optimize what functions?

A

Cardiac output and blood pressure.

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5
Q

Epinephrine

What dose is used during cardiac arrest?

A

1 mg IV/IO every 3-5 min

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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6
Q

Vasopressin

What dose is used during cardiac arrest?

A

40 units once

May replace 1st or 2nd Epi dose.

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7
Q

What drug & doseage is given in VF/ pulseless VT, unresponsive to CPR, Shock, and Vasopressors?

A

Amiodarone

(Class III antiarrhythmic)

300 mg inital dose

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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8
Q

Amiodarone

If needed one additional dose can be considered for VF/ Pulseless VT, what is the dose?

A

Amiodarone

(Class III antiarrhythmic)

150 mg inital dose

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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9
Q

If amiodarone is not available, providers may administer what other antiarrhythmic drug and dosage for VF/ Pulseless VT?

A

Lidocain

(Class 1B antiarrhythmic)

1 to 1.5 mg/kg IV/IO inital dose

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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10
Q

Lidocaine

Repeat if indicated, during cardiac arrest from VF/VT, at what doseage?

A

0.5 to 0.75 mg/kg every 5-10min

to a max accumulation of 3mg/kg

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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11
Q

Maximum total accumulation dosage of Lidocaine?

A

3 mg/kg

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12
Q

What drug and dosage is given to recurrent or persistent VF/ pulseless VT associated with torsades de pointes(TdP)?

A

Magnesium Sulfate

1 to 2 g IV/IO diluted in 10 mL D5W, given over 5 to 20 min.

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13
Q

Magnesium sulfate

Indicated for patients with known or suspected low serum magnesium due to?

A
  1. Alcoholism
  2. Malnutrition
  3. Hypomagnesemic states
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14
Q

Magnesium sulfate

What is the dosage for TdP with a pulse or AMI with hypomagnesemia?

A

Loading Dose:

1 - 2 g mix in 50 to 100 mL of D5W, infused over 5 to 60 min.

Follow up Dose:

0.5 to 1g /hr (titrate to control TdP)

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15
Q

Drugs that may be used in Immediate Post-Cardiac Arrest Care?

A

Oxygen

Epinephrine IV infusion

Dopamine IV infusion

Norepinephrine IV infusion

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16
Q

During Immediate Post-Cardiac Arrest Care when treating hypotention (SBP <90 mmHg).

What is first-line treatment of choice?

A

IV Bolus 1-2 L NS or LR

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17
Q

Epinephrine

Infusion dosage for persistent hypotention (SBP <90 mmHg) after inital NS or LR bolus?

A

0.1 - 0.5 mcg/kg/min IV infusion

titrated to achieve minimum SBP >90mmHg or a MAP >65 mmHg

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18
Q

Dopamine

Infusion dosage for persistent hypotention (SBP <90 mmHg) after inital NS or LR bolus?

A

5 - 10 mcg/kg/min IV infusion

titrated to achieve minimum SBP >90mmHg or a MAP >65 mmHg

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19
Q

Treatment for severe hypotention (SBP <70mmHg) after inital NS or LR bolus?

A

Norepinephrine

0.1 - 0.5 mcg/kg/min IV infusion

titrated to achieve minimum SBP >90mmHg or a MAP >65 mmHg

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20
Q

Drugs and dosages that can be given during PEA?

A

Epinephrine 1mg IV/IO q 3-5min

or

Vasopressin 40units once

or

Other medication based upon review of Hs & Ts

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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21
Q

Immediate medication treatment for Acute Coronary Syndromes?

A
  1. O2 , if SpO2 <94%, at a rate 4L/min, titrate
  2. Asprine (4 baby) =324 mg
  3. Nitroglycerin 1 tab or spray every 3-5 min (for a total 3)
  4. Mophrine, if chest discomfort unresponsive to nitro.
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22
Q

Asprine

How is given to ACS patients with nausea, vomiting, active peptic ulcer disease, or other GI tract disorder?

A

300 mg suppositories

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23
Q

Nitroglycerin

Contraindications?

A
  1. SBP <90 mmHg
  2. HR must be 50 -100 bpm
  3. Phosphodiesterase use past 24h (Viagra)
  4. Tadalafil use past 48h (Cialis)
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24
Q

Analgesic drug and dosage of choice for STEMI ?

A

Morphine Sulfate

2 - 4 mg IV every 5 - 10 min

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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25
Q

Analgesic drug and dosage for symtomatic UA/NSTEMI not responsive to nitro?

A

Morphine Sulfate

1 - 5 mg IV prn

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

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26
Q

Naloxone HCl

Typical IV dose for?

A

0.04 -0.4 mg, titrate until ventilation adequate.

27
Q

Naloxone HCl

Typical IM/SQ dose for?

A

0.4 - 0.8 mg

28
Q

Drugs that may be used during Adult Bradycardia (with pulse)?

A

Atropin

Dopamine infusion

Epiephrine infusion

29
Q

First-line drug and dosage of choice for Adult Bradycardia (w/ pulse) ?

A

Atropine

inital dose: 0.5 mg IV/IO bolus

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

30
Q

Atropine

Repeat dosages for Adult Bradycardia (w/ pulse)?

A

Atropine

0.5 mg IV/IO q 3 - 5min

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

31
Q

Atropine

Maximum accumulating dosage?

A

3 mg

32
Q

Second-line treatment options for symptomatic Adult Bradycardia (w/ pulse) after Atropine is ineffective?

A

Choose of one of the following:

TCP

Dopamaine

Epinephrine

33
Q

Dopamine

Infusion dosage for symptomatic Adult Bradycaria (w/pulse)?

A

2 - 10 mcg/kg/min

34
Q

Epinephrine

Infusion dosage for symptomatic Adult Bradycaria (w/pulse)?

A

2 - 10 mcg/min

35
Q

Atropine

Maximum accumulating dosage?

A

0.04 mg/kg (3mg)

36
Q

Atropine

Maximum accumulating dosage?

A

0.04 mg/kg (3mg)

37
Q

Atropine

Dosage of <0.5 mg may result in?

A

Paradoxically, rsulting in further slowing of the heart.

38
Q

Atropine

Do not rely on for Adult Bradycardia associated with what type(s) of AV blocks?

A

2nd Degree type II

or

3rd Degree (complete block)

39
Q

Atropine

Use caustiously in the presence of acute coronary ischemia or MI, why?

A

Atropine use increase HR that may worsen ischemia or increase infarct size.

40
Q

Perferred inital interventions treatment for terminating narrow QRS adult tachycardia?

A

Vegal Maneuvers

(valsalva <em>or</em> carotid sinus massage)

Adenosine

Expert consult / Transport

41
Q

Vagal maneuvers alone terminate about what percentage of SVT?

A

25%

Adenosine is required for the remainder.

42
Q

Adenosine

Increase AV block and will terminate approx. what percent of reentry arrhythmias within 2 min.?

A

90%

43
Q

Adenosine

Will not terminate what arrhythmias?

A

Atrial flutter or Atrial Fibrillation

but will slow AV conduction allowing identifaction of flutter and fibrillation waves.

44
Q

Adenosine

Can be used as test to determine AFib or AFlutter presence to do what?

A

Change therapy to beta-blockers or calcium channel blockers.

45
Q

What inital drug and dosage is treatment for narrow-QRS SVT not responsive to vegal maneuvers?

A

Adenosine

6 mg IVP (lg vein) over 1sec

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

46
Q

Adenosine

If SVT does not convert 1-2 min, give second dose at?

A

Adenosine

12 mg IVP (lg vein) over 1sec

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

47
Q

Adenosine

Contraindicated in patients with?

A
  • Poison/ drug induced tachycardia.
  • 2nd and 3rd degree heart blocks
  • Asthma; may cause bronchospasm
48
Q

Calcium Channel Blocker

What are the two major categories?

A

Dihydropyridine

Non dihydropyridine

49
Q

Calcium Channel Blocker

What category affects the peripheral vasculature causing dialation, with minimal SA/AV effect?

A

Dihydropyridine

50
Q

Calcium Channel Blocker

What category decreases HR and myocardial contractility, slows SA/AV conduction?

A

Non dihydropyridine

51
Q

Calcium Channel Blocker

What alternative drug(s) (after adenosine) used to terminate reentry SVT with narrow QRS associated with AFib / AFlutter?

A

Verapamil

or

Ditiazem

52
Q

Diltiazem

What is the inital dose for acute rate control of stable narrow-QRS tacycardia nonresponsive to vagal maneuvers or adenosine?

A

15 -20 mg (0.25 mg/kg) IV bolus over 2min.

wait 15 min.

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

53
Q

Diltiazem

May give an addtional dose of for acute rate control in 15min, what’s the dose?

A

20 - 25 mg (0.35 mg/kg) IV bolus over 2min.

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

54
Q

Verapamil

What is the dose for acute rate control of stable narrow-QRS tacycardia nonresponsive to vagal maneuvers or adenosine?

A

5 mg IV bolus over 3min every 15min.

till accumulated dose of 30 mg

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

55
Q

Calcium Channel Blocker

Shoudn’t be given to patients with?

A

SBP <90 mmHg

&

Wide-QRS tachycardias

56
Q

Beta Blocker

What alternative drug(s) (after adenosine) used to terminate reentry SVT with narrow QRS associated with AFib / AFlutter?

A

Propranolol

57
Q

Propranolol

<em>(Beta </em>Blocker)

What is the dosage for acute rate control of stable narrow-QRS tacycardia nonresponsive to vagal maneuvers or adenosine?

A

0.5 - 1 mg IV bolus over 1min

repeated as needed to accumulated dosage of 0.1 mg/kg

Remember:

With peripheral inj. 20mL flush and elevate 10-20 sec

58
Q

What are the antiarrhythmic infusions used for stable wide-QRS tachycardia?

A

Procainamide

Amiodarone

Sotalol

59
Q

Procainamide

What is the infusioin dose for recurrent VF/VT stable wide-QRS tacycardia?

A

20 mg/min IV infusion

to accumulated max dose of 17 mg/kg

60
Q

Procainamide

What are the indication to stop infusion?

A

Arrhythmia suppression

Hypotention

QRS widens by 50%

Total max accumulated dose, 17 mg/kg, is given

61
Q

Amiodarone

What is the rapid infusioin dose for recurrent life-threating VT wide-QRS tacycardia arrhythmias?

A

150 mg IV over 10 min. repeat q 10 min PRN

after arrhythmia termination follow with maint. infusion

1 mg/min for first 6h

62
Q

Amiodarone

What is the slow infusioin dose for recurrent life-threating VT wide-QRS tacycardia arrhythmias?

A

360 mg IV over 6hrs

(1mg/minfor 6hrs)

63
Q

Sotalol

What is the infusioin dose for recurrent life-threating VT wide-QRS tacycardia arrhythmias?

A

100 mg (1.5mg/kg) over 5min.

avoid if prolonged QT