ACLS Drugs Flashcards
Drugs given by peripheral I.V. route take how long to reach central cirulation?
1 to 2 min.
If any drug is given peripherally I.V., administer it as follows:
- Give as bolus inj. unless otherwise specified
- Follow with 20mL flush
- Elevate extremity for 10-20 sec
Vasopressors
What drugs are used during cardiac arrest?
Epinephrine (1:10,000)
or
Vasopressin
Vasopressors
Optimize what functions?
Cardiac output and blood pressure.
Epinephrine
What dose is used during cardiac arrest?
1 mg IV/IO every 3-5 min
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec
Vasopressin
What dose is used during cardiac arrest?
40 units once
May replace 1st or 2nd Epi dose.
What drug & doseage is given in VF/ pulseless VT, unresponsive to CPR, Shock, and Vasopressors?
Amiodarone
(Class III antiarrhythmic)
300 mg inital dose
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec
Amiodarone
If needed one additional dose can be considered for VF/ Pulseless VT, what is the dose?
Amiodarone
(Class III antiarrhythmic)
150 mg inital dose
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec
If amiodarone is not available, providers may administer what other antiarrhythmic drug and dosage for VF/ Pulseless VT?
Lidocain
(Class 1B antiarrhythmic)
1 to 1.5 mg/kg IV/IO inital dose
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec
Lidocaine
Repeat if indicated, during cardiac arrest from VF/VT, at what doseage?
0.5 to 0.75 mg/kg every 5-10min
to a max accumulation of 3mg/kg
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec
Maximum total accumulation dosage of Lidocaine?
3 mg/kg
What drug and dosage is given to recurrent or persistent VF/ pulseless VT associated with torsades de pointes(TdP)?
Magnesium Sulfate
1 to 2 g IV/IO diluted in 10 mL D5W, given over 5 to 20 min.
Magnesium sulfate
Indicated for patients with known or suspected low serum magnesium due to?
- Alcoholism
- Malnutrition
- Hypomagnesemic states
Magnesium sulfate
What is the dosage for TdP with a pulse or AMI with hypomagnesemia?
Loading Dose:
1 - 2 g mix in 50 to 100 mL of D5W, infused over 5 to 60 min.
Follow up Dose:
0.5 to 1g /hr (titrate to control TdP)
Drugs that may be used in Immediate Post-Cardiac Arrest Care?
Oxygen
Epinephrine IV infusion
Dopamine IV infusion
Norepinephrine IV infusion
During Immediate Post-Cardiac Arrest Care when treating hypotention (SBP <90 mmHg).
What is first-line treatment of choice?
IV Bolus 1-2 L NS or LR
Epinephrine
Infusion dosage for persistent hypotention (SBP <90 mmHg) after inital NS or LR bolus?
0.1 - 0.5 mcg/kg/min IV infusion
titrated to achieve minimum SBP >90mmHg or a MAP >65 mmHg
Dopamine
Infusion dosage for persistent hypotention (SBP <90 mmHg) after inital NS or LR bolus?
5 - 10 mcg/kg/min IV infusion
titrated to achieve minimum SBP >90mmHg or a MAP >65 mmHg
Treatment for severe hypotention (SBP <70mmHg) after inital NS or LR bolus?
Norepinephrine
0.1 - 0.5 mcg/kg/min IV infusion
titrated to achieve minimum SBP >90mmHg or a MAP >65 mmHg
Drugs and dosages that can be given during PEA?
Epinephrine 1mg IV/IO q 3-5min
or
Vasopressin 40units once
or
Other medication based upon review of Hs & Ts
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec
Immediate medication treatment for Acute Coronary Syndromes?
- O2 , if SpO2 <94%, at a rate 4L/min, titrate
- Asprine (4 baby) =324 mg
- Nitroglycerin 1 tab or spray every 3-5 min (for a total 3)
- Mophrine, if chest discomfort unresponsive to nitro.
Asprine
How is given to ACS patients with nausea, vomiting, active peptic ulcer disease, or other GI tract disorder?
300 mg suppositories
Nitroglycerin
Contraindications?
- SBP <90 mmHg
- HR must be 50 -100 bpm
- Phosphodiesterase use past 24h (Viagra)
- Tadalafil use past 48h (Cialis)
Analgesic drug and dosage of choice for STEMI ?
Morphine Sulfate
2 - 4 mg IV every 5 - 10 min
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec
Analgesic drug and dosage for symtomatic UA/NSTEMI not responsive to nitro?
Morphine Sulfate
1 - 5 mg IV prn
Remember:
With peripheral inj. 20mL flush and elevate 10-20 sec