Acid-Base / Electrolytes / Fluids Flashcards
What are the four primary acid-base disorrders?
Metabolic Acidosis
Metabolic Alkalosis
Respiratory Acidosis
Respiratory Alkalosis
Respiratory acid-base disorders bring primary changes in ___ and secondary (compensatory) changes in _____.
CO2
HCO3-
Metabolic acid-base disorders bring primary changes in ___ and secondary (compensatory) changes in _____.
HCO3-
CO2
What primary acid-base disorder is indicated by the ABG below….
7.21/30/100/15
A. Metabolic Acidosis
B. Metabolic Alkalosis
C. Respiratory Acidosis
D. Respiratory Alkalosis
A. Metabolic Acidosis
What is the compensatory response in a metabolic acidosis?
Decrease CO2 concentration through hyperventilation
What processes can result in a Metabolic acidosis?
Lactic Acidosis DKA Ingestion (Methanol, Ethylene Glycol, ASA) Renal Failure Diarrhea (HCO3- Loss)
What primary acid-base disorder is indicated by the ABG below….
7.50/50/100/30
A. Metabolic Acidosis
B. Metabolic Alkalosis
C. Respiratory Acidosis
D. Respiratory Alkalosis
B. Metabolic Alkalosis
What is the compensatory response in metabolic alkalosis?
Increased CO2 concentration through hypoventilation
What processes can lead to metabolic alkalosis?
- TPN Administration
- Vomiting (H+ loss)
- Loop diuretics
- HCO3- Administration
What primary acid-base disorder is indicated by the ABG below….
7.14/56/100/27
A. Metabolic Acidosis
B. Metabolic Alkalosis
C. Respiratory Acidosis
D. Respiratory Alkalosis
C. Respiratory Acidosis
What is the compensatory response in a respiratory acidosis?
Increased HCO3- buffering in the kidneys
What processes can lead to a respiratory acidosis?
Alveolar hypoventilation V/Q mismatch Alterations in CNS respiratory drive Respiratory muscle fatigue Pulmonary disease Mechanical ventilation
If an intubated and mechanically ventilated patient developed a respiratory acidosis, would this be the result of hypoventilation or hyperventilation?
How could this be corrected?
Hypoventilation (The patient is not breathing fast enough)
This can be corrected through increasing the ventilation rate
What primary acid-base disorder is indicated by the ABG below….
7.56/25/100/18
A. Metabolic Acidosis
B. Metabolic Alkalosis
C. Respiratory Acidosis
D. Respiratory Alkalosis
D. Respiratory Alkalosis
What is the compensatory response to a respiratory alkalosis?
Decreased HCO3- production in the kidneys
Is respiratory alkalosis commonly due to hypoventilation or hyperventilation?
Hyperventilation
What processes can cause respiratory alkalosis?
- Pain
- CVA
- Anxiety
- Trauma (Flail Chest)
- Hypoxemia, Altitude
- Pulmonary Edema
- Heart Failure
- Sepsis
- Mechanical Ventilation
- Over-correcting Metabolic acidosis
What are causes of a WAGMA (Wide anion gap metabolic acidosis)?
MUDPILES
Methanol Uremia (renal failure) Diabetic ketoacidosis Propylene glycol Infection, inborn errors of metabolism Lactic acidosis Ethylene glycol Salicylate
A 65 y.o. male s/p CABG is intubated and placed on ventilation in the ICU. Following intubation, an ABG is drawn which shows…..
7.27/55/250/25(-2)/100%
What is the primary acid/base disorder?
Is this likely a result of?
How could this be corrected?
Respiratory Acidosis
This is likely a result of hypoventilation (holding onto too much CO2)
Increase the ventilation rate
A 40 y.o female involved in a single vehicle MVA arrives in the ED. On exam she is found to have a fail chest. As respiratory failure seems imminent, she is intubated. Following intubation, an ABG is drawn which shows….
7.54/24/370/22/100%
What is the primary acid/base disorder?
Is this likely a result of?
How could this be corrected?
Respiratory Alkalosis
This is likely due to mechanical hyperventilation. (Losing too much CO2)
Decrease the ventilation rate
A 6 y.o. male is brought into the ED complaining of emesis, abdominal pain, and polyuria. A UA is ordered which shows a large amount of glucose and the presence of ketones. This is concerning and prompts an ABG draw, which shows…..
7.25/16/131/7/99%
What is the primary acid/base disorder?
What is the likely underlying condition this patient has?
How are they trying to compensate?
Metabolic Acidosis
This patient likely has undiagnosed DM and is now presenting in DKA
He was trying to compensate by hyperventilating and ‘blowing down’ his CO2 levels
_______ are IV fluids that contain water, dextrose, Na+, Cl-, and other electrolytes
Crystalloids
______ _____ contain mostly Na+ and Cl- but also have lactate, K+, and Ca2+
Lactated Ringer’s (LR)
______ contain packed red blood cells, pooled human plasma (5% albumin, 25% albumin), semisynthetic glucose polymers (dextran), and semisynthetic hydroxyethyl starch (hetastarch)
Colloids
Are colloids more likely to remain in the intravascular space or the interstitial space?
Intravascular
Why should colloids be avoided in patient who are requiring fluid resuscitation (ie: dehydration)?
Colloids will draw water out of the interstitial space
When would symptoms of intravascular fluid depletion likely manifest?
Once 15% (750 mL) of blood volume is lost
What is the recommended ‘fluid’ of choice in fluid resuscitation?
Crystalloids
What are the signs and symptoms of intravascular fluid depletion?
- Tachycardisa
- Hypotension
- Orthostatic
- AKI (Increased BUN/sCr)
- Dry Mucus Membranes
- Decreased Skin Turgor
- Reduced Urine Output
- Dizziness
____ water is also referred as D5W and is metabolized to water and CO2 in the body
Free Water (D5W)
What THREE things are considered when adjusting maintenance fluids?
- Input
- Output
- Insensible Loss
Which ‘fluid’ is commonly used for maintenance fluids?
A. Crystalloids
B. Colloids
C. Free Water (D5W)
C. Free Water (D5W)
Increased osmolarity would likely result in fluid shift ______ (out of/into the cell, cell _______ (hydration/dehydration and _______ (shrinkage/growth)
Out of
Dehydration
Shrinkage
Decreased osmolarity would likely result in fluid shift ______ (out of/into the cell, cell _______ (hydration/dehydration) and _______
Into
Hydration
Hemolysis
In what THREE ways can fluid be classified in terms of osmolarity?
- Hypertonic (Water out of the cells)
- Isotonic
- Hypotonic (Water into the cell)
What are TWO common uses for hypertonic saline?
- TBI with increased ICP and MAP
2. Symptomatic Hyponatremia (AMS, Coma)