Acid-Base/Electrolytes Flashcards
Which of the following statements is true regarding hemoglobic hypoxia?
a. It is defined as the decreased oxygen bound to hemoglobin or decreased hemoglobin
b. There is a defect in the delivery of oxygen to the blood
c. The PaO2 is decreased
d. Carbon monoxide has less affinity for hemoglobin than oxygen
a. It is defined as the decreased oxygen bound to hemoglobin or decreased hemoglobin
Reference: Stockham and Scott. Pg 583
Which of the following is a strong cation in the strong ion difference system?
a. Chloride
b. Bicarbonate
c. Lactate
d. Sodium
d. Sodium
Reference: Stockham and Scott. Pg 586
Which of the following is a cause of a titrational metabolic acidosis?
a. Ethylene glycol toxicity
b. Laryngeal paralysis
c. Pneumothorax
d. Fever
a. Ethylene glycol toxicity
Reference: Stockham and Scott. Pg 574
Which of the following correctly describes the acid-base disturbance? pH 7.25; pCO2 50 mmHg; HCO3- 35 mmol/L
A) Respiratory acidosis with compensatory metabolic alkalosis
B) Respiratory alkalosis with compensatory metabolic acidosis
C) Metabolic acidosis with compensatory respiratory alkalosis
D) Metabolic alkalosis with compensatory respiratory acidosis
A) Respiratory acidosis with compensatory metabolic alkalosis
Source: Stockham and Scott, pp. 574-578 (2nd ed.).
In which of the following conditions/diseases would you expect an animal to have respiratory alkalosis?
A) Pulmonary fibrosis
B) Myasthenia gravis
C) Pneumothorax
D) Gram-negative septicemia
D) Gram-negative septicemia
Source: Stockham and Scott, pp. 575-577 (2nd ed.).
Which combination of factors would most likely cause an animal to have paradoxical aciduria?
A) Metabolic acidosis, hyperchloremia, and hypovolemia
B) Metabolic alkalosis, hyperchloremia, and hypovolemia
C) Metabolic alkalosis, hypochloremia, and hypovolemia
D) Metabolic acidosis, hypochloremia, and hypovolemia
C) Metabolic alkalosis, hypochloremia, and hypovolemia
Source: Stockham and Scott, p. 576 (2nd ed.).
Hypoventilation causes respiratory acidosis due to which of the following shifts in acids and bases:
a. ↑PCO2 and ↓H+
b. ↑PCO2 and ↑H+
c. ↑HCO3- and ↓H+
d. ↑HCO3- and ↑H+
b. ↑PCO2 and ↑H+
Stockham, S. L., Scott, M. A. (2008), Fundamentals of Veterinary Clinical Pathology. 2nd ed. Ames, Iowa: Blackwell Publishing, pg. 563
Carbon dioxide (CO2) produced in the tissues through a variety of metabolic pathways is carried in the blood in which of the following forms:
a. Dissolved, estimated as PvCO2
b. As HCO3- in erythrocytes
c. As H2CO3 bound to albumin
d. A and B
e. A, B, andC
d. A and B
a. Dissolved, estimated as PvCO2
b. As HCO3- in erythrocytes
Stockham, S. L., Scott, M. A. (2008), Fundamentals of Veterinary Clinical Pathology. 2nd ed. Ames, Iowa: Blackwell Publishing, pg. 566
Which of the following is not considered a weak anion (in equilibria in physiologic fluids):
a. Bicarbonate
b. Phosphate
c. Lactate
d. Carbonate
c. Lactate
Stockham, S. L., Scott, M. A. (2008), Fundamentals of Veterinary Clinical Pathology. 2nd ed. Ames, Iowa: Blackwell Publishing, pg. 586
A metabolic acidosis with appropriate respiratory compensation is characterized by which one of the following?
A. High PaCo2; high HCO3-
B. High PaCo2; low HCO3-
C. Low PaCo2; high HCO3-
D. Low PaCo2; low HCO3-
D. Low PaCo2; low HCO3-
Which one of the following is true regarding base excess?
A. Base excess is the amount of base that needs to be added to return the sample to a normal pH.
B. Base excess is only affected by volatile acids such as CO2.
C. Base excess reflects only the respiratory component of an acid-base disturbance.
D. Base excess reflects only the metabolic component of an acid-base disturbance.
D. Base excess reflects only the metabolic component of an acid-base disturbance.
Respiratory compensation for metabolic disorders occurs relatively __________; renal compensation for respiratory disorders occurs relatively _________.
A. Quickly; quickly
B. Quickly; slowly
C. Slowly; quickly
D. Slowly; slowly
B. Quickly; slowly
A right shifted Oxygen-hemoglobin dissociation curve is characterized by which of the following?
a. Increased [H+], decreased [2,3 DPG], increased temperature and increased PCO2
b. Decreased [H+], increased [2,3 DPG], increased temperature and increased PCO2
c. Increased [H+], increased [2,3 DPG], increased temperature and increased PCO2
d. Increased [H+], decreased [2,3 DPG], increased temperature and decreased PCO2
c. Increased [H+], increased [2,3 DPG], increased temperature and increased PCO2
( Fundamentals of veterinary clinical pathology: pg 568)
Which of the following conditions can result in a respiratory alkalosis?
a. Septicemia
b. Right to left shunts
c. Myasthenia gravis
d. Diaphragmatic hernia
a. Septicemia
Fundamentals of veterinary clinical pathology: pg 577
Which of the following reflects the pO2 at room air, arterial blood and venous blood.
a. 100mmHg, 90mmHg, 45mmHg
b. 760mmHg, 90mmHg, 40mmHg
c. 150mmHg, 90mmHg, 40mmHg
d. 150mmHg, 40mmHg, 20mmHg
c. 150mmHg, 90mmHg, 40mmHg
Fundamentals of veterinary clinical pathology: pg 573
Which one of the following alterations in blood gas values can result from excessive heparin in the sample?
a. Increased [H+]
b. Increased PO2
c. Increased PCO2
d. Increased [HCO3-]
b. Increased PO2
Stockham and Scott (2nd Ed.), Chap. 10, p. 573.
Which type of acidosis is described as a decreased strong ion difference resulting from an excess of free water?
a. Dilutional acidosis
b. Organic acidosis
c. Secretory acidosis
d. Titrational acidosis
a. Dilutional acidosis
Stockham and Scott (2nd Ed.), Chap. 10, p. 574.
Which of the following conditions, concurrent to alkalosis, can cause paradoxical aciduria?
a. Hypokalemia and hyperchloremia
b. Hypovolemia and hyperkalemia
c. Hypovolemia and hypochloremia
d. Hypochloremia and hyponatremia
c. Hypovolemia and hypochloremia
Stockham and Scott (2nd Ed.), Chap. 10, p. 576.
The Henderson Hassalbalch equation describes which of the following?
a) pH is proportional to the [HCO3-]/[pCO2]
b) a small K value is associated with strong acids
c) pH is inversely proportional to the concentration of bicarbonate divided by the partial pressure of carbon dioxide
d) pH is proportional to the [pCO2]/[HCO3-]
a) pH is proportional to the [HCO3-]/[pCO2]
Source: Page 561. Stockham, S.L. and M.A. Scott, Fundamentals of veterinary clinical pathology. 2nd ed2008, Ames, Iowa: Blackwell Pub
Which of the following are correct reference intervals (lower and upper limit) on a venous blood gas test?
a) Base excess 0-20
b) pH 7.0-7.5
c) pCO2 35-45
d) Total CO2 25-35
e) Anion gap 8-15
c) pCO2 35-45
RI are as follows, pH 7.35-7.45, pCO2 35-45, BE -2-8, total CO2 18-26, AG 13-22. Source: from Dr. Wiedmeyer’s powerpoint and from the NOVA machine in the ICU.
What are the 3 independent variables in Stewart’s strong ion difference model?
a) Strong ion difference, total concentration of weak acids and pCO2
b) Strong ion difference, bicarbonate concentration and pCO2
c) Strong ion difference, bicarbonate concentration and total concentration of weak acids
d) Strong ion difference, total sodium concentration and total chloride concentration
a) Strong ion difference, total concentration of weak acids and pCO2
Source: page 585. Stockham, S.L. and M.A. Scott, Fundamentals of veterinary clinical pathology. 2nd ed2008, Ames, Iowa: Blackwell Pub
Which of the following is not included in the Strong Ion Difference?
A. Sodium
B. Potassium
C. Chloride
D. Bicarbonate
D. Bicarbonate
Dr. Wiedmeyer’s ppt
Carbon dioxide is a component of the carbonic acid equilibrium. Which of the following is NOT true of carbon dioxide?
A. Exists as part of a closed system
B. Higher concentration leads to increased [H+]
C. It is an independent variable
A. Exists as part of a closed system
Dr. Wiedmeyer’s ppt
Which of the following does not lead to an anticipated increase in anion gap?
A. Ethylene glycol toxication
B. Protein losing nephropathy leading to hypoalbuminemia
C. Decreased GFR leading to increased inorganic phosphates
D. Hypoperfusion leading to hyperlactatemia
B. Protein losing nephropathy leading to hypoalbuminemia
Lecture slides from 11.13.14 Wiedmeyer Acid-Base powerpoint
Which of the following is a true statement?
a. Acids accept hydrogen ions
b. Bases donate hydrogen ions
c. The body has a closed system of buffering
d. The body maintains a slightly alkaline pH
d. The body maintains a slightly alkaline pH
Source: The basics of Acid/Base – Charles Wiedmeyer