Acid/Base Cases Flashcards
Respiratory =
opposite direction arrows bc it compensates the fastest
Metabolic =
same direction arrouws bc it compensates a lot slower
Anion Gap =
Na - (Cl+HCO3)
Elevated anion gap
AT MUD PILES Alcohol Toluene Methanol/Metformin Uremia DM ketoacidosis Paraldehyde Isoniazide/Iron/Ischemia Lactic acidosis Ethylene glycol Salicylate/Starvation
Non-elevated anion gap
USED CAR Urethral diversion Saline exogenous Exogenous acid (HCl) Diarrhea Cholestyramine/carbonic anhydrase inhibitors Addison's disease Renal tubular acidosis
Metabolic acidosis Treatment Options
Consider treating when pH less than 6.9 with sodium bicarbonate or THAM/tromethamine
Sodium bicarbonate AE
decrease intracellular pH
Overcorrect alkalosis
Sodium and water overload
Tromethamine (THAM) AE
Respiratory depression
Extravasation- inflammation, vascular spasm, necrosis
Hyperkalemia and hypoglycemia
CAUTION IN LIVER OR KIDNEY FAILURE
Metabolic Alkalosis
If pH > 7.6 use
HCl
HCl AE and pH goal
Use until pH = 7.5
Infusion reaction
Overcorrection –> acidosis
Respiratory Acidosis
O2 less than 40 or CO2 > 80 mmHg
Oxygenation
COPD Goal O2
88-92%
Respiratory alkalosis
pH > 7.6
Mechanical ventilation with analgesia and sedation
For an acute change in respiratory acidosis we expect the
HCO3 to go up 1 mEq for every 10 mmHg increase in paCO2 if the patient is compensating appropriately.