Acid Base Balance Flashcards

1
Q

What percent water are adults, infants and elderly

A

60, 74 and 45

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2
Q

What are nonelectrolytes

A

organic molecules like glucose lipid and urea that are not charged

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3
Q

ICF has more what ions

A

K+ and A-

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4
Q

ECF has more what ions

A

Na+ and Cl-

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5
Q

What pressures control the movement of fluids between compartments

A

osmotic and hydrostatic

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6
Q

ECF increase osmolarity causes water to go

A

out of cell

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7
Q

ECF decrease osmolarity causes water to go

A

into the cell

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8
Q

What is blood osmolarity

A

concentration of chemical particles in fluid part of blood

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9
Q

What does an increase in plasma osmolarity causes

A

water to move out of cell

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10
Q

What is obligatory water loss

A

occur at a constant irrespective of body state of hydration

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11
Q

What is hyponatremia

A

low sodium causing decreased urine production and increased aldosterone

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12
Q

What can reverse hypotonic hydration

A

hypertonic saline or mannitol infusion

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13
Q

What is edema

A

fluid build up in tissues

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14
Q

What are some types of edema

A

peripheral, pulmonary, cerebral, and macular

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15
Q

How does ECF concentration remain consistent

A

water volume may need to change

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16
Q

What does aldosterone do to Na and K

A

increase Na and K

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17
Q

What does no aldosterone cause

A

lose too much Na

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18
Q

What is Addison’s disease

A

adrenal glands do not produce enough cortisol and aldosterone

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19
Q

What is ANP

A

atrial natriuretic peptide

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20
Q

What does ANP do

A

dilate afferent arterioles and constrict efferent, increases GFR

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21
Q

How do estrogen and progesterone effect regulation of sodium

A

increase resorption

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22
Q

Why do glucocorticoids promote edema

A

stimulates Na resorption

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23
Q

What does aldosterone do to the DCT

A

causes the reabsorption of sodium and secretion of potassium

24
Q

Increased plasma potassium concentration do

A

stimulates secretion of aldosterone

25
What are the symptoms of hyperkalemia
heart palpitations, shortness of breath, chest pain, nausea, or vomiting
26
What are the symptoms of hypokalemia
respiratory failure and death
27
What happens to neuromuscular excitation when hypocalcemia occurs
increased excitation
28
what is the normal pH of blood
7.35-7.45
29
What is blood alkalosis
arterial pH is above 7.45
30
What is blood acidosis
arterial pH is below 7.0
31
Chemical acid-base buffers
molecules that prevent H+ concentration changes by binding to H+ ions and releasing them
32
What is the alkaline reserve
available bicarbonate ions
33
What is most of the body's buffer system
proteins
34
What are the physiological buffering systems
respiratory and renal systems
35
What is the problem with alkalosis
too little H+, pH too high
36
How do the lungs resolve blood alkalosis
slows breathing
37
What is the result of hypoventilation
decrease pH
38
What is the result of hyperventilation
increase pH
39
How does the renal mechanism work
excretes or reabsorbs HCO3-
40
To reabsorb HCO3- the kidneys must do what
secrete H+
41
What must the kidneys do to excrete HCO3-
retain H+
42
What replenishes the alkaline reserve
replenished by the kidney
43
What is respiratory acidosis
shallow or slow breathing results in CO2 accumulating in the blood
44
What is respiratory alkalosis
hyperventilation releasing CO2 faster than produced
45
What causes metabolic acidosis
alcohol, lactic acid accumulation and ketosis, HCO3- levels would be low
46
What causes metabolic alkalosis
vomiting, intake of bases, or constipation
47
If the PCO2 is above 45 mmHg what is happening
respiratory acidosis (most common imbalance)
48
If PCO2 is below 35 mm Hg what is happening
respiratory alkalosis, usually hyperventilating
49
What effect does acidosis have on the nervous system
depresses it
50
what effect does alkalosis have on the nervous system
overexcites it, convulsions and respiratory arrest
51
What is respiratory compensations
changes in breathing rate and depth due to metabolic imbalances
52
What is renal compensation
changes in renal function due to metabolic imbalances
53
What are the signs of respiratory compensation
low CO2 levels and low HCO3- levels
54
Why does diabetes cause acidosis
ketone bodies are released when liver breaks down fat for fuel and these bodies acidic
55
Why do infants have more acid base balance issues
low residual volumes, high rate of fluid intake, high metabolic rate