Acid/Base Balance Flashcards
Stomach pH
1.5 - 20
Throwing up = alkolotic
losing acid
Colon pH
7.9-8.5
basic
losing base –> becoming acidic
what is ph?
potential hydrogen
hydrogen concentration –>
lower pH = more acidic, higher pH = more alkaloid
ROME
Resp opposite
Metabolic equal
acidic –> alkalotic
pH : 7.35 - 7.45
PaCO2 : 45 - 35
HCO3 : 22 - 26
what is a base and what is acid?
CO2 = acid –> because its carbonic acid
Hydrogen/ HCO3 = base
Chemical buffer system
First line of defense
immediate response
- bicarbonate, phosphate, protein
Physiological buffer System
Second line of defense against imbalances
respiratory - minutes to hours ***
renal - hours to days **
What does Renal / HCO3 excrete?
H excretion!
what does respiratory excrete?
CO2 !
What is the most effective regulator of ph?
THE RENAL
What is O2?
% of oxygen that has hgb attached to it
ex: o2 sat is 98%, 2% of the blood doesnt have oxygen attached
Metabolic acidosis
- Diarrhea
- Increased RR (Kussmal) respiratory is trying to fix it and compensate!
- N/V
- decreased BP
- cold skin
- Dysrhythmia* –> hyperkalemia! we hold onto acid because we want to excrete K
Metabolic Acidosis - Cause
- Kidney injury (cant release acid)
- Diarrhea, intestinal fistula
- increased Cl –> more negative ions! body tries to fix it by holding onto more hydrogen
- DKA
- Renal Failure
- Lactic acidosis –> tissue hypoxia (cardiac arrest/shock)*
Metabolic acidosis TX
- Give Bicarb
- Watch potassium (usually hyperkalemia)
- ECG for cardiac dysrhythmias
- Serum Calcium levels (will be low)
- Correct b4 treating acidosis
Anion gap
8- 12
sum of all positive minus all negative charged ions