Acid-Base Flashcards
Substance that releases H+ ion when dissolved in water
acid
Substance that binds free H+ ions in solution
base
Most common base in body
HCO3- (bicarbonate)
Most common acid in body
H2CO3- (carbonic acid)
Ratio of carbonic acid to bicarbonate
1:20
What organ controls bicarbonate levels?
kidneys
What organ controls carbon dioxide?
lungs
How is CO2 formed?
carbohydrate metabolism
Incomplete breakdown of fatty acids that are metabolized are called
ketoacids
Once bicarbonate is in the ECF, it is kept at a level ___ times greater than that of carbonic acid
20
What are buffers composed of?
Chemicals or proteins
Two common chemical buffers?
Bicarbonate and phosphate
Major cell protein buffer?
Hemoglobin
H+ binds to hemoglobin, resulting in fewer H+ ions in the blood, bringing pH back to normal.
Second line of defense when chemical buffers cannot prevent change in blood pH
Respiratory system
Breathing controls Amt of free hydrogen ions by controlling amt of CO2 in arterial blood.
What causes hyperventilation?
CO2 is elevated in brain blood and tissue. Receptors trigger neurons to increase rate and depth of breathing.