Acetylcholine (ACh) Flashcards
What type of chemical is ACh?
Neurotransmitter
Define Cholinergic
Part of the body affected by ACh
Define Anticholinergic
A substance that interferes with ACh
Source tissues
Motor neurons, parasympathetic nervous system, brain
Target tissues
Skeletal muscles, brain, organs
Receptors (2)
Nicotinic and Muscarinic
Agonists
Nicotine, Muscarine, Cholinesterase Inhibitors
Antagonists
Tubocurarine, atropine
Chemical formula
C7H16NO2
Molar mass
126.2 grams
Use at Neuromuscular junction
Activates muscles
Primary neurotransmitter of ______
Parasympathetic nervous system
Uses in brain
Neurotransmitter and neuromodulator
Does ACh penetrate the lipid membrane?
No
Does ACh pass the blood-brain barrier?
No
Explain movement of ACh through brain
Starts in basal forebrain and moves to cerebral cortex and hippocampus for cognitive function
What does ACh do in the peripheral nervous system?
Activates muscles