ACE modules Flashcards

1
Q

MAP or SBP is a product of?

A

SVR x CO

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2
Q

Cardiac output is a product of ?

A

CO = HR x SVR

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3
Q

Factors affecting SVR?

A
  • Vascular tone
  • Blood viscosity
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4
Q

Mechanisms of BP regulation?

A
  • Fast neural response
  • Slow humoral response
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5
Q

Sensory information about BP is detected by ?

A
  • Stretch receptors - Baroreceptors
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6
Q

Location of baroreceptors?

A
  • carotid sinus
  • aortic arch
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7
Q

Pathways of baroreceptor sensing of BP information?

A
  • Baroreceptors
  • Afferent automonic fibres to medulla
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8
Q

The vasomotor center?

A

Area in the medulla involved in regulation of BP

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9
Q

Determinants of BP?

A
  • Arteriolar diameter
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10
Q

Vasomotor centre mechanism?

A
  • Activation of SNS
  • Innervation of arterioles
  • Smooth muscle contraction
  • Vasoconstriction
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11
Q

Activators of vasomotor centre resulting in increased BP?

A
  • Pain
  • Emotion
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12
Q

Inhibitors of VMC resulting in lowering of BP?

A
  • Increased firing of baroreceptors
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13
Q

Components of hormonal control of BP?

A
  • Adrenaline / Noradrenaline (Adrenal medulla)
  • Vasopressin (Hypothalamus)
  • Angiotensin II (Renin-Angiotensin-Aldosterone system)
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14
Q

Actions of hormonal control of blood pressure? Compensatory mechanisms?

A
  • Positive inotropy
  • Vasoconstriction
  • Fluid retention
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15
Q

Natural substances lowering BP? Potent arteriolar vasodilators?

A
  • Histamine
  • Nitric oxide
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16
Q

Sympathetic nerve endings ?

A
  • Release Noradrenaline acting on alpha-1-receptors to cause vasoconstriction
17
Q

Location of alpha-1-adrenoceptors?

A
  • Skin
  • Gut
  • Kidney