ACE INHIBITORS Flashcards
What 5 drugs types are used to treat hypertension?
1) ACE- Angiotensin-Converting Enzymes
2) ARBs- Angiotensin II-Receptor Blockers
3) Calcium - Channel Blockers
4) Vasodilators
5) Renin Inhibitors
Angiotensin-Converting Enzymes (ACE) Inhibitors end with
pril
Angiotensin II-Receptor Blockers (ARBs) end with
sartan
What do ACE inhibitors do?
antihypertensive agents that act in the lungs to prevent the conversion of angiotensin I into angiotensin II, which is a potent vasoconstrictor.
Therapeutic Action of ACE Inhibitors
By preventing the production of angiotensin II which is a potent vasoconstrictor and a stimulator of aldosterone release, blood pressure is decreased with resultant loss of serum sodium and fluid but with a slight increase in serum potassium
What can ace inhibitors be combined with?
Diuretics and Digoxin
What effect do ACE Inhibitors have on diabetic nephropathy?
decreased in stimulation of angiotensin receptors in the kidney will slow down the damage in the renal artery.
Are ACE Inhibitors allowed during pregnancy?
NO
Adverse effects of ACE Inhibitors GI
irritations, ulcer, constipation, liver injury
Adverse effects of ACE Inhibitors GU?
renal insufficiency, renal failure, proteinuria
Adverse effects of ACE Inhibitors GU?
renal insufficiency, renal failure, proteinuria
Adverse effects of ACE Inhibitors CV?
reflex tachycardia, chest pain, heart failure, cardiac arrhythmias
Adverse effects of ACE Inhibitors EENT?
rash, alopecia, dermatitis, photosensitivity