Accessory Sensory Organs Flashcards
Secretin
Stimulated by stomach acid in intestine -> SI secretin -> bicarbonate secretion from pancreas and liver -> neutralization of intestinal acid
Synthesized in cytoplasmic secretory granules of S cells, found mainly in mucosa of duodenum
GIP
Gastric inhibitory polypeptide
Cleaved by K cells found in mucosa of duodenum
In response to glucose induced hyperosmolarity of duodenum
GIP stimulates insulin secretion
CCK
Cholecystokinin
Stimulated by fa and aa
Releases pancreatic enzymes and contraction of gallbladder
Proteins: trypsin, chymotrypsin, and carboxypeptidase
Fat: lipase
Sugars: amylase
RNA/DNA: ribonuclease/deoxyribonuclease
Synthesized by I cells in mucosal epithelium of SI and secreted in duodenum
From preprocholecystokinin family
Endocrine pancreas
Alpha: glucagon
Beta: insulin
Delta: somatostatin
Epsilon: ghrelin
Liver disease symptoms
Pale stool Dark urine Bilirubin deposits Swelling Excessive fatigue Bruising