ABX MOA

Question 1

Penicillins

Answer 1

Cell Wall Synthesis- PBP (PCN binding proteins)

Question 2

Cephalosporins

Answer 2

Cell Wall Synthesis- PBP (PCN binding proteins)

Question 3

Vancomycin, Telavancin, Oritavancin, Dalbavacin

Answer 3

Cell Wall Synthesis- blocks peptidoglycan polymerization by binding to D-alanyl-D-alanine

Question 4

Beta-lactamase Inhibitors

Answer 4

Cell Wall Synthesis

Question 5

Carbapenems

Answer 5

Cell Wall Synthesis- PBP (PCN binding proteins)

Question 6

Aztreonam

Answer 6

Cell Wall Synthesis- PBP (PCN binding proteins)

Question 7

Polymycin

Answer 7

Cell Wall Synthesis

Question 8

Aminoglycosides

Answer 8

Protein Synthesis Inhibitors- 30s and 50s ribosomal subunits

Question 9

Fluoroquinolones

Answer 9

DNA Synthesis Inhibitor of topoisomerase IV and DNA gyrase

Question 10

Macrolides

Answer 10

Protein Synthesis Inhibitors- 50S ribosomal subunit

Question 11

Chloramphenicol

Answer 11

Protein Synthesis Inhibitors- 50S ribosomal subunit

Question 12

Clindamycin (Cleocin)

Answer 12

Protein Synthesis Inhibitors- 50S ribosomal subunit

Question 13

Linezolid, Tedizolid

Answer 13

Protein Synthesis Inhibitors- 23S ribosomoal RNA of 50S ribosomal subunit

Question 14

Tetracyclines

Answer 14

Protein Synthesis Inhibitors- 30S ribosomal subunit

Question 15

Metronidazole/ Flagyl (CAREFUL WITH WARFARIN)

Answer 15

DNA Synthesis Inhibitor= protein synthesis inhibitor

Question 16

Bactrim (CAREFUL WITH WARFARIN)

Answer 16

Folic Acid synthesis inhibitors

Question 17

Daptomycin (Cubicin)

Answer 17

Protein synthesis inhibitor

Question 18

Tigecycline (Tygacil)

Answer 18

Protein Synthesis Inhibitors- 30S ribosomal subunit

Question 19

Rifampin (Xifaxan)

Answer 19

RNA synthesis Inhibitors

Question 20

Nitrofurantoin

Answer 20

Bacterial cell wall inhibitor