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Antibiotics Baby > ABX and MOA stuff > Flashcards

ABX and MOA stuff Flashcards

1
Q

What are the beta lactams?

A

PCN’s and Cephalosporins (except Vancomycin)

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2
Q

What abx are water soluble.

A

PCN (except for nafcillin)

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3
Q

Are protein synthesis inhibitors bacteriostatic or bactericidal?

A

Bacteriostatic (except for aminoglycosides)

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4
Q

All cocci are gram ?

A

Positive (but for neisseria)

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5
Q

All bacilli are gram ?

A

Negative (but for A,B,T,D or anthrax, botulism, tetanus, and diphtheria)

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6
Q

What abx are used for intracellular bacteria?

A

Tetracyclines, macrolides.

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7
Q

What abx do you want to avoid using with pregnancy? FATS

A

Fleuroquinolones, aminoglycosides, tetracyclines, Sulfonamides

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8
Q

Which drugs are most associated with C. Diff (pseudomembranous colitis)? Think “C”

A

Clindamycin, cephalosporins, ciprofloxacin

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9
Q

What other class of abx should you avoid if a pt has a PCN allergy?

A

Cephalosporins

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10
Q

What drugs are bacteriostatic? ECSTaTIC

A

Erythromycin, clindamycin, sulphonamides, tetracyclines, trimethoprim, chloramphenicol

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11
Q

What drugs are bactericidal? Very Finely Proficient At Cell Murder

A

Vancomycin, fleuroquinolones, penicillins, aminoglycocides, cephalosporins, metronidazole

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12
Q

Gram + cocci include…

A

Staph and strep

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13
Q

Gram - cocci include…

A

Coxiella, rickettsia, neisseria, gonorrhea

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14
Q

Gram + rods include…

A

Corynebacterium, listeria, bacillus, actinomyces, nocardia, clostridium

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15
Q

Gram - rods include…

A

Bordetella, pseudomonas, francisella, brucella, bartonella, helicobacter, shigella, legionella, enterobacter, yersinia, proteus, haemophilus, salmonella, klebsiella, vibrio, serratia, escherichia, bacteroides

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16
Q

Vancomycin

A

G+

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17
Q

Clindamycin

A

G+, anaerobes

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18
Q

Amoxicillin/ampicillin

A

G+, weak G-

19
Q

Augmentin/unasyn

A

G+, anaerobes, G-

20
Q

Nafcillin

A

G+

21
Q

Zosyn

A

G+, anaerobes, G-, PSEUDOMONAS

22
Q

Carbapenems

A

G+, anaerobes, G-, PSEUDOMONAS (except ernepenem)

23
Q

Fleuroquinolones

A

G+, weak anaerobes, G-, weak PSEUDOMONAS

24
Q

1st gen ceph - cephalexin, cefazolin

A

G+, weak G-

25
Q

3rd gen ceph - cephtriaxone, cefdinir

A

G+, G-, PSEUDOMONAS

26
Q

Bactrim

A

G+, G-

27
Q

Metronidazole

A

Anaerobes

28
Q

Aminoglycocides

A

G-, PSEUDOMONAS

29
Q

Tetracyclines

A

G+, weak anaerobes, G-, ATYPICALS

30
Q

Macrolydes

A

G+, weak G-, ATYPICALS

31
Q

Treatment for legionella

A

Azithro or Fluoroquin

32
Q

Flu treatment

A

Oseltamavir

33
Q

Pneumocystitis pneumonia treatment

A

Bactrim

34
Q

Pertussis treatment

A

Erythromycin (macrolide)

35
Q

Sarcoidosis

A

Corticosteroid

36
Q

alpha 1` antitrypsin deficiency

A

Prolastin

37
Q

chlamydial pneumonia

A

Erythro (macrolide) or doxy (tetracycline)

38
Q

Alpha 1 blockers. What are they? How do they work? What do you use them for?

A

Zosins. They stop alpha 1 and RELAX PROSTATE and BLADDER NECK. Used for BPH

39
Q

Alpha 1 agonists. What are they? How do they work? What do you use them for?

A

Alpha 1 vasoconstriction. (think sudafed). Decongestant

40
Q

Alpha 2 agonists. What are they? How do they work? What do you use them for?

A

Clonidine and methyldopa. Stimulates A2 receptors which DECREASES SNS activity. Given in HTN. Side effects are dry mouth, sedation, fatigue.

41
Q

Beta 1 receptor agonists. What are they? How do they work? What do you use them for?

A

Dopamine and dobutamine. This works as an INOTROPE (contractility) on the heart as well as the kidneys to secrete renin and increase renal blood flow. Give with severe CHF.

42
Q

Beta 2 agonists. What are they? How do they work? What do you use them for?

A

Albuterol, terbutaline, salmeterol, metaproterenol. Beta 2 receptor stimulation which RELAXES BRONCHIAL SMOOTH MUSCLE and UTERINE RELAXATION. Use with asthma and COPD. Terbutaline is good to slow premature labor AND help with priapism!!!

43
Q

Beta blockers. Which are the B1 only? B1 and B2?

A

B1 only are Atenolol, Metoprolol (most cardio selective), esmolol. B1 and B2 are propanolol, nadolol, sodalol. A1 and B1/2 are labetalol and carvedilol. Use caution with DM as it can block hypoglycemia.

Antibiotics Baby (1 decks)

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