ABX Flashcards

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1
Q

What four antibiotics compose the Beta Lactam drug class?

A

Penicillin
Cephalosporins
Carbapenems
Monobactams

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2
Q

How do Beta Lactam drugs work?

A

Inhibit penicillin-binding proteins that normally assemble the peptidoglycan layer that surrounds bacteria

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3
Q

Penicillin G is given via what route?

A

IV

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4
Q

Penicillin V is given via what route?

A

Orally

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5
Q

1st generation cephalosporins provides strength against what time of bacteria?

A

Gram positive

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6
Q

Cefdinir is a _____ generation cephalosporin

A

third

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7
Q

Cefazolin is a _____ generation cephalosporin

A

1st

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8
Q

Ceftriaxone is what generation cephalosporin?

A

3rd

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9
Q

Cefapime is a _____ generation cephalosporin?

A

4th

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10
Q

Cephalexin (Keflex) is a ____ generation cephalosporin?

A

First

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11
Q

What type of bacteria are most susceptible to 1st generation cephalosporins?

A

Gram Positive (staph/strep)

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12
Q

Imipenem, meropenem, doripenem, and ertapenem are what drug class?

A

Carbapenems

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13
Q

Carbapenems are often the _____ line of defense against many organisms that are resistant to other antimicrobial agents.

A

Last

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14
Q

This drug class (Azteronam) kills what type of bacteria? What is this drug class?

A

Gram negative

Monobactams

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15
Q

Vancomycin belongs to what drug class?

A

Glycopeptides

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16
Q

Glycopeptides are larger than other abx, so they cannot pass through porins in the outer membrane, so their activity is restricted to what type of bacteria?

A

Gram positive

17
Q

Vancomycin is ______ absorbed in the GI tract, so must be given IV. Rapid infusion can cause?

A

poorly

Red Man Syndrome

18
Q

Daptomycin is a cyclic _________ antibiotic. Daptomycin is not active in the _____, so it should not be used to treat pneumonia.

A

Lipopeptide

Pneumonia