Absorption Flashcards
The movement and modification of a drug or medication inside the body
Pharmacokinetics
ADME stands for?
Absorption, Distribution, Metabolism, Excretion
How medications are absorbed in the body
Absorption
How the medication is processed in the body
Metabolism
How many medications get to where they are going in the body
Distribution
How the medication gets out of the body and into the “potty”
Elimination
How a medication goes from the site of administration to the bloodstream
Absorption
The medication goes down its concentration gradient, so from an area of higher concentration to an area of lower concentration
Passive transport
Allows small, lipid-soluble, and nonpolar medications to freely move across the membrane
Passive diffusion
Allows larger, water-soluble, and polar medications to move across the membrane through transport proteins like channels and carrier proteins
Facilitated diffusion
Requires no energy
Passive transport
Requires energy in the form of ATP
Active transport
Some medications need to be transported through active transport against their concentration gradient, so from an area of lower concentration to an area of higher concentration
Active transport
Made up of a bilayer of phospholipid molecules
Cell membrane
Phospholipids are?
amphiphilic “both loving”
Their “head” is?
Hydrophilic (it likes water)
Their “tail” is?
lipophilic (it loves fats)
