ABSITE - Thoracic Flashcards

1
Q

Where does the azygous v. run?

A

along the R side

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2
Q

Where does the azygous v. empty?

A

into the SVC

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3
Q

At what level does the thoracic duct cross midline?

A

T4-5

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4
Q

what side does the thoracic duct run along?

A

R side

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5
Q

What doest he thoracic duct empty into?

A

L subclavian v. @ junction w/ IJV

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6
Q

Phrenic n. - ant or posterior to hilum?

A

anterior

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7
Q

Vagus n. - ant or posterior to hilum?

A

posterior

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8
Q

R lung lobes?

A

RUL, RML, RLL

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9
Q

L lung lobes

A

LUL, LLL, lingula

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10
Q

L lung lobes vs R lung lobes - total lung volume

A

R ~55%; L ~45%

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11
Q

what are the accessory mm of respiration?

A

SCM, levators, serratus posterior, scalenes

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12
Q

function of type 1 pneumocytes

A

gas exchange

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13
Q

function of type 2 pneumocytes

A

surfactant production (phosphatidylcholine, which keeps alveoli open)

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14
Q

what are pores of kahn?

A

they allow direct air exchange btwn alveoli

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15
Q

what is the S phase?

A

protein synthesis, chromosomal duplication

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16
Q

What are the phases of the cell cycle?

A

G1, S, G2, M

17
Q

What are the phases of mitosis?

A

Prophase, metaphase, anaphase, telophase

18
Q

Prophase

A

centromere attachment, centriole and spindle formation, nucleus disappears

19
Q

metaphase

A

chromosome alignment

20
Q

anaphase

A

chromosomes separate

21
Q

telophase

A

separate nucleus reforms around each set of chromosomes

22
Q

G1

A

growth factors affect cell during G1

23
Q

What is G0 of cell cycle?

A

cells are quiescent; can enter G1

24
Q

Steroid hormones

A

bind receptors in the cytoplasm

25
Q

thyroid hormones

A

bind receptors in nucleus

26
Q

DNA PCR

A

use oligonucleotides to amplify specific DNA sequences

27
Q

Purines

A

A,G (adenine, guanine)

28
Q

Pyrimidines

A

C,T,U (RNA only) (cytosine, thymidine, uracil)

29
Q

What binds guanine and cytosine?

A

3 Hydrogen bonds

30
Q

What binds adenine to thymidine/uracil?

A

2 hydrogen bonds

31
Q

Glycolysis generates ____ from 1 glucose molecule

A

2 ATP and 2 pyruvate molecules

32
Q

Krebs/citric acid cycle produces ___ from ____

A

NADH and FADH2 from 2 pyruvate molecules (electron transport molecules)

33
Q

1 glucose produces __ ATP

A

~36

34
Q

what is gluconeogenesis?

A

process of lactate (via Cori cycle) and amino acids (especially alanine) are converted to glucose; activates during starvation and stress times

35
Q

Fat and lipids are not available for gluconeogenesis because ___

A

acetyel CoA (product of fat metabolism) can’t be converted back to pyruvate

36
Q

what is the Cori cycle?

A

liver converts muscle lactate into glucose; pyruvate is a key player in this process

37
Q

which signalling pathways utilize 2nd messengers?

A

Phospholipase C, protein kinase A, MAPK/ERK pathway

38
Q

Protein kinase C pathway is activated by …

A

Calcium, DAG

39
Q

Protein kinase A is activated by…

A

cAMP