ABS PREP Flashcards

1
Q

High Resolution Anoscopy for identifying AIN lésions.

A

Anoscopy can assist in macroscopic disease identification, but high-resolution anoscopy is most sensitive and specific at identifying AIN lesions. Patients who have anal cytology (similar to Pap smear) that has low- or high-grade squamous intraepithelial lesion (LSIL or HSIL) are recommend to undergo high-resolution anoscopy.

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2
Q

What benign breast lesions need to under go excisional biopsy after core needle biopsy?

A

Other benign breast lesions that are indications for excisional biopsy include atypical lobular hyperplasia, radial scar, columnar cell hyperplasia with atypia, papillary lesion, lack of concordance between the appearance of mammographic lesion and pathologic histology, and nondiagnostic specimen

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3
Q

What are absolute contraindications to BCT?

A

Diffuse suspicious or malignant-appearing microcalcifications
Inflammatory breast cancer
Multicentric disease (precluding single excision)
Persistently positive resection margins despite multiple attempts at re-excision
Pregnancy (radiation therapy is contraindicated during pregnancy; however, breast conservation therapy is acceptable for some second- and third-trimester patients who can receive radiation after delivery)
Previous breast or chest radiation (that would exceed the total safe radiation dose with BCT)

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4
Q

What are relative contraindications to BCT?

A

Large tumors (> 5 cm)
Systemic scleroderma
Active systemic lupus erythematosus

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5
Q

What are components of Gail Model?

A

Age (valid for women 35–85 years old)
First live birth (age)
First menstrual period (age)
Number of first-degree relatives (mother/sister/daughter) with breast cancer
Number of previous breast biopsies and history of breast biopsies with atypical hyperplasia
Race/ethnicity

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