ABs 2 Flashcards
Fluriquinolones action
targets DNA
stop supercoiling of DNA
egs of Fluriquinolones
Ciprofloxacin
Levofloxacin
side effects of fluriquinolones (ciprofloxacin, levofloxacin)
tendon damage
seizures
Quinolones action
Targets DNA
breaks DNA strands
egs of Quinolones
Metronidazole
side effects of Metronidazole
alcohol interaction
metallic taste
NOT IN PREGNANT WOMEN
action of rifampicin
targets mRNA
attacks RNA polymerase
side effects of rifampicin
orange fluids
hepatitis
action of tetracyclines
targets protein synthesis
bacteriostatic
eg of tetracyclines
doxycycline
side effects of doxycycline
destroys gut flora => 2ndary infections
NOT IN PREGNANT WOMEN
NOT IN <12YRS
Action of doxycycline
targets protein synthesis
bacteriostatic
action of ciprofloxacin/levofloxacin
targets dna
stop supercoiling of dna
action of metronidazole
targets dna
breaks dna strands
action of rifampicin
targets mRNA
targets rna polymerase
eg of aminoglycosides
gentamicin
aminoglycosides action
targets protein synthesis
bactericidal
- binds to bacterial ribosomes
side effects of gentamicin
kidney
CN VIII
MONITOR BLOOD LEVELS
action of gentamicin
targets proteinsynthesis
bactericidal
- binds bacterial ribosomes
egs of macrolides
erythromycin
clarithromycin
azythromycin
egs of penicillins
fluoxacillin
amoxicillin
co-amoviclav
action of penicillin
targets cell wall synthesis
stops x-linkage
has b-lactam rings
action of macrolides
targets protein synthesis
binds to ribosomes
=> bacteriostatic
what can you defos use in pregnancy
macrolides
penicillin
cephalosporins
eg of cephalosporins
cefalexin
action of cephalosporins
targets cell wall synthesis
stops x-linkage
baceticidal
eg of glycopeptides
vancomycin
action of cefalexin
targets cell wall synthesis
stops x-links
bactericidal
action of glycopeptides
targets cell wall synthesis
stops peptidoglycan synthesis
action of vancomycin
targets cell wall synthesis
stops peptidoglycan synthesis
