ABG Interpretation Flashcards

1
Q

Normal values for pH?

A

7.35-7.45

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2
Q

Normal values for pH?

A

7.35-7.45

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3
Q

Normal values for pCO2?

A

4.5-6.0 kPa

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4
Q

Normal values for pO2?

A

11-13 kPa

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5
Q

Normal values for HCO3?

A

22-25 mmol/L

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6
Q

Normal values for base excess?

A

-2 to +2

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7
Q

Normal values for lactate?

A
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8
Q

Normal values for SaO2?

A

> 95%

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9
Q

Steps 1-5 in interpreting ABG?

A
  1. Assess oxygenation?
  2. Determine pH status
  3. Determine respiratory component (PaCO2)
  4. Determine metabolic component (HCO3-)
  5. Combine (compensation)
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10
Q

pH low, PaCO2 high?

A

Respiratory acidosis

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11
Q

pH high, PaCO2 low?

A

Respiratory alkalosis

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12
Q

pH low, HCO3- low?

A

Metabolic acidosis

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13
Q

pH high, HCO3- high

A

Metabolic alkalosis

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14
Q

How can acidosis be compensated for?

A

Respiratory - increased RR to blow off CO2 (results in reduced CO2)
Metabolic - increased bicarb production by kidney (high bicarb)

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15
Q

Causes of respiratory acidosis?

A

Hypoventilation in:

  • Lung disease (COPD, asthma, pulmonary oedema)
  • CNS depression
  • Mechanical lung dysfunction (obesity, gullian barré, myasthenia gravis)
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16
Q

Causes of respiratory acidosis?

A

Hypoventilation in:

  • Lung disease (COPD, asthma, pulmonary oedema)
  • CNS depression
  • Mechanical lung dysfunction (obesity, gullian barré, myasthenia gravis)
17
Q

Normal values for pCO2?

A

4.5-6.0 kPa

18
Q

Normal values for pO2?

A

11-13 kPa

19
Q

Normal values for HCO3?

A

22-25 mmol/L

20
Q

Normal values for base excess?

A

-2 to +2

21
Q

Normal values for lactate?

A
22
Q

Normal values for SaO2?

A

> 95%

23
Q

Steps 1-5 in interpreting ABG?

A
  1. Assess oxygenation?
  2. Determine pH status
  3. Determine respiratory component (PaCO2)
  4. Determine metabolic component (HCO3-)
  5. Combine (compensation)
24
Q

pH low, PaCO2 high?

A

Respiratory acidosis

25
Q

pH high, PaCO2 low?

A

Respiratory alkalosis

26
Q

pH low, HCO3- low?

A

Metabolic acidosis

27
Q

pH high, HCO3- high

A

Metabolic alkalosis

28
Q

How can acidosis be compensated for?

A

Respiratory - increased RR to blow off CO2 (results in reduced CO2)
Metabolic - increased bicarb production by kidney (high bicarb)

29
Q

How can alkalosis be compensated for?

A

Respiratory - decreasing resp rate to retain CO2 (high CO2)

Metabolic - decreasing bicarb production by kidney (low HCO3-)

30
Q

Causes of respiratory acidosis?

A

Hypoventilation in:

  • Lung disease (COPD, asthma, pulmonary oedema)
  • CNS depression
  • Mechanical lung dysfunction (obesity, gullian barré, myasthenia gravis)
31
Q

Causes of respiratory alkalosis?

A

Hyperventilation in:

  • Anxiety
  • Hypoxia
  • Acute pulmonary insult (PE, pneumonia, asthma attack, pulmonary oedema)
32
Q

Causes of metabolic acidosis?

A

CHECK ANION GAP = (Na+ + K+)-(Cl- + HCO3-)
Normal = 3-12

Increased = new acid added to body (lactic acidosis, DKA, sepsis, aspirin OD)
Normal = retaining H+ (renal tubular acidosis, Addison's) or losing HCO3- (diarrhoea)
33
Q

Causes of metabolic alkalosis?

A

Acid loss in:

  • Chloride responsive: vomiting, diuretics, corticosteroids
  • Chloride resistant: any hyperaldosterone state (Cushing’s, hypokalaemia)
34
Q

Pathophysiology behind type 1 respiratory failure?

A

Caused by V/Q mismatch:

  • Low V/Q = areas of lung are perfused with deoxygenated blood but not ventilated with O2 (i.e. airway obstruction - mucus plug in asthma/COPD, airway collapse in emphysema)
  • High V/Q = areas of lungs venilated with oxygen but not perfused with deoxygenated blood (i.e. block in blood flow - PE)
35
Q

Cause of type 2 respiratory failure?

A

Alveolar hypoventilation - oxygen cannot get in and CO2 cannot get out.
Obstructive lung diseases, restrictive lung diseases, decreased respiratory drive, neuromuscular disease, thoracic wall disease.