ABEM Flash cards
Ehrlichiosis - organism and transmission?
Ehrlichia (gram neg, intracellular), lone star tick (Amblyomma)
Babesiosis - organism and transmission
protozoan parasite, Ixodes tick
tick borne relapsing fever - organism and transmission
spirochete Borrelia hermsii, Ornithodoros tick
tick borne relapsing fever - clinical syndrome
fever, HA, myalgias, arthralgias, jaundice x3-6 days; then afebrile, x several cycles.
colorado tick fever - organism and transmission?
RNA virus, wood tick Dermacentor
class I hemorrhage: EBL and VS?
<750 cc’s. normal HR/BP, normal to elevated pulse pressure
class II hemorrhage: EBL and VS?
750-1500 cc’s. HR 100-120, BP normal, decreased pulse pressure
class III hemorrhage: EBL and VS?
> 1500 c’s. elevated HR, low BP, decreased pulse pressure
MR murmur
apex, systolic murmur, radiates to axilla
most common traumatic valvular injury
aortic valve
diastolic murmurs
AR, MS, pulmonary regurg, PDA (continuous)
systolic murmurs
AS, MR/TR, VSD, MVP, PDA (continuous)
XR for toxic megacolon
dilated colon to 6 cm, loss of haustra, thumbprinting
black widow spider bite symptoms
mostly local (including diaphoresis near site), occasional systemic. Caused by release of ACh and NE.
bark scorpion (Centruroides) envenomation symptoms
localized pain, can cause severe neurologic sx in children (neuroexcitatory of sympathetic and parasympathetic nervous system causing ataxia, cranial nerve dysfunction, hypersalivation, muscle jerking, and unusual eye movements)
GIB after aortic aneurysm repair = what diagnosis
aortoenteric fistula
When is a patient’s risk for future stroke highest following a transient ischemic attack?
first 2 days
Montaggia
prox ulnar fx and prox radial (head) dislocation
smallpox vs chicken pox
smallpox = all the same age. chickenpox = lesions of varying ages
indication, and absolute contraindication to physostigmine
anticholinergic syndrome. C/I if QRS >100 or if Na channel blockade
dry socket syndrome and treatment
pain 2-3 days after dental extraction due to loss of protective clot. Irrigate with chlorhexidine 0.12% or warmed NS. If e/o infection, PCN (or clinda if PCN allergy)
Best test for giardia
stool antigen test
cyproheptadine is the treatment for?
serotonin syndrome
antibiotics assoc with non convulsive status
PCNs
odynophagia in HIV patient: organisms?
Candida or CMV
cancer and lethargy/AMS
Hypercalcemia
recurrent food impactions and GERD despite PPI/antacids
eosinophilic esophagitis (can develop strictures)
superficial vs partial thickness burns?
superficial is painful, red, and blanching.
partial is non-blanching, bright red, and may have blisters
how to treat amenorrhea 2/2 anorexia nervosa
weight gain - no OCPs!
red flag back symptoms
fever, weakness, weight loss/night sweats, hx of cancer, bowel/bladder, trauma
treatment for mild impetigo
Mupirocin ointment (or retapamulin)
predominant electrolyte abnormality in anorexia? treatment?
hypophos. treat promptly (PO vs IV depending on severity) to help prevent refeeding syndrome
Korsakoff syndrome
apathy, confabulation, anterograde and retrograde amnesia
abdominal pain, palpable purpura
HSP
diseases associated with HSP
meckel’s, lymphoma, celiac, IBD
treatment for contact lens related corneal abrasions
topical anti-pseudomonal (cipro, oflox, tobramycin)
diffuse vesicular lesions in various stages of development
varicella
hard signs of vascular neck injuries
pulsatile bleeds, expanding hematoma, thrills/bruits, neurologic deficits, shock
sx of scombroid poisoning
flushing, GI sx, conj injection 30 mins after eating. Fish may be peppery, bitter, metallic
sx of ciguatera poisoning
GI + neuro sx (GI precedes neuro sx). pathognomonic sx = cold allodynia and worsening/recurrence with alcohol.
3 topical cycloplegic drugs
cyclopentolate, scopolamine, homatropine
first line treatment for obstruction + coffee bean sign on abd XR
dx: sigmoid volvulus. first line tx = sigmoidoscopy (if no gangrene)
1 risk factor for IPV homocide
access to firearms
LVH
R (aVL) > 11 mm
S V1 + R V5/V6 > 35 mm
S deep + S V4 > 23 mm in M / 28 mm in F
dose of recomb factor VIII in life-threatening bleeds
50 units/kg (replaces 100% of factor levels)
chads2vasc: what ages give you points?
65-74 = 1 point. >75 = 2 points
chads2vasc: what sex give you points
female = 1, male = 0
chads2vasc: what conditions give you points
HTN, DM, stroke/TIA/VTE, vascular disease (MI, PAD, aortic plaque), CHF
xray findings suggestive of SBO
bowel dilation >3 cm, prominent plicae circulares, and multiple air-fluid levels.
first line abx for mastitis
keflex, dicloxacillin (against MSSA). If MRSA suspected, give Bactirim.
acute lung abscess: most likely organism?
oral anaerobes
what age for femur IO?
<1 year
Ehrlichiosis - clinical syndrome?
constitutional sx + hematologic abnormalities (thrombocytopenia/leukopenia). Usually no rash!
drugs that trigger gout
ASA, cyclosporine, diuretics
ketosis/ketonuria with normal AG = ?
isopropyl alcohol
electrolyte disturbances in tumor lysis
hyperuricemia, hyperK, hyperphosphatemia, hypoCa
Fluorescein pattern for UV keratitis
Multiple punctate erosions
hard signs of vascular injury
pulsatile bleed, diminished distal pulse, expanding hematoma, thrill/bruit
MOA of isoproterenol
beta-1 and beta-2 agonist (Increased heart rate. Increased heart contractility. Relaxation of bronchial, gastrointestinal, and uterine smooth muscle.)
normal CSF WBC, glucose, protein
WBC <5, glucose 60% of serum, <200 mg/dL
1 inherited bleeding disorder
vWD
1 inherited clotting (hypercoagulable) disorder
factor V leiden
EKG findings to look for in syncope
block, WPW, long QT, Brugada, HOCM, AVRD
pityriasis rosea description and treatment
herald patch followed by many scaly red plaques/patches. ?reactivation of HHV6/7, treat pruritis
distinguishing factors between bullous pemphigoid and pemphigus vulgaris
BP slightly older (>65), less mucosal involvement, neg Nikolsky.
PV involves mucosae and has +Nikolsky
neuro sx that worsen with fever, hot bath, warm environment
Uhthoff sign - think MS
1 organism causing osteomyelitis assoc with puncture wounds
Pseudomonas
treatment of pediatric lead poisoning
Treatment depends on sx and blood lead levels. If symptomatic, ADMIT. If asymptomatic and elevated blood lead levels, outpatient chelation
SIRS criteria
HR >90
RR >20
WBC >12, <4, or >10% bands
Temp >38 or <36
difference between labyrinthitis and vestibular neuritis
no tinnitus or hearing loss in vestibular neuritis
definition of delta pressure for acute compartment syndrome. What delta is concerning?
diastolic BP - compartment pressure. <30 is concerning!
CSF findings in MS
oligoclonal bands
what kind of bundle/fascicular blocks are an indication for pacemaker placement following acute anterior MI?
RBBB + LAFB (has potential to progress to CHB)
PT/INR measures what clotting factors?
I, II, V, VII, X
age for walking? (developmental milestones)
~13 months
when to suspect NAT in spiral fracture of tibia
less than walking age, fx is proximal rather than distal
opiates that require renal dosing
morphine, tramadol, codeine, meperidine
reversal agent for Xa inhibitors
andexanet alfa, 4 factor PCC
DDx for wide QRS
hyperK, Na channel blockade, BBB, PM, WPW, ventricular beats, nonspecific IVCD
Marcus Gunn vs Argyl Robertson pupil
Marcus Gunn = APD (think optic neuritis/MS)
Argyl Robertson = non reactive but accommodates (think neurosyphilis)
antibiotics which can trigger myasthenic crisis
fluoroquinolones, macrolides, aminoglycosides
what kind of parasite is Strongyloides stercoralis?
nematode (roundworm)
site of infection of Strongyloides stercoralis?
small intestine. Larvae migrate through skin
clinical syndrome of Strongyloides stercoralis?
typically asymptomatic, sometimes GI/dysentery. Larvae migrate through skin –> rash/pruritis.
Hyperinfestation in immune compromised or elderly can be deadly. (PNA, septicemia, meningitis, ileus)
who gets tetanus IVIG as prophylaxis?
<3 vaccines + complicated wound.
complicated wound = contaminated (dirt/feces/saliva), crush, burn, frostbite, puncture, missile
number 1 cause of arterial embolism?
AFib
What level is sensation over medial malleolus?
L4 nerve root
Weakness of great toe extension localizes to what nerve root?
L5
Bilateral subconjunctival hemorrhage in infants
raises concern for NAT
Facial swelling, cough, sob, HA
SVC syndrome
Earliest sign of HACE?
Ataxia (this is also the most specific finding)
Mainstay if PTSD pharmacotherapy
SSRI
Adjunct pharmacotherapy for specific sx of PTSD?
Prazosin for nightmares;
propranolol for anxiety/sympathetic activation symptoms
INTRACTIBLE seizures of neonate
Consider possible pyridoxine deficiency
GI sx, then shock, acidosis, hepatotoxicity, AMS/seizure
Iron toxicity
Specific Signs of orbital fracture in trauma
Enophthalmos, diplopia, infraorbital numbness, orbital step off
First steps to work up possible PM lead displacement
EKG, CXR
First line ppx after exposure to N. meningitidis
CTX, rifampin, ciprofloxacin
erythema marginatum is due to what disease
acute rheumatic fever
first medicine to give to treat pheo
alpha blockers before beta blockers
first medicine to give when treating thyroid storm
BB, then methimazole or PTU, then KI
risk factors for endometrial cancer
estrogen and more exposure to thickened endometrium
obesity, nulliparity, early menarche / late menopause, anovulatory cycles
1 risk factor for developmet of hepatorenal syndrome
SBP
what volume of contrast should be used for cystourethrogram in trauma?
400 cc
cave exploration + respiratory sx =
histo (flu like illness, CXR with hilar LAD)
construction work + respiratory sx =
coccidiomycosis (fever/myalgias, CXR with LAD/focality/effusions)
alpha blocker for use in acute treatment of pheo
phentolamine or phenoxybenzamine
complications of therapeutic hypothermia
coagulopathy/bleeding, arrhythmias, hyperglycemia/insulin resistance, infection, “cold diuresis”
uncomplicated withdrawal - how many hours after last drink?
1-6 h
alcoholic hallucinosis occurs how many hours after last drink?
onset 12-24h after last drink, can last 1-2 days
withdrawal seizures occur how many hours after last drink?
6-48 hours
DTs occur how many hours after last drink?
onset 72-96 hours after last drink
treatment for baclofen withdrawal seizures
BZD
unstable pregnant patient with CP and widened mediastinum. What test to order next?
TEE for dx of possible AO dissection
ETT for regular sized neonate
3.0 uncuffed
what is a helminth
parasitic worm (types = roundworm/nematode, fluke/trematode, tapeworm/cestode)
PERC vs Wells
PERC has age, hormone use
Wells has immobilization, hx cancer, PE #1 ddx
calculated serum osms
2*Na + glucose/18 + BUN/2.8 + etoh/4.6
mg/dl
toxin ketosis without acidosis
isopropyl alcohol
effects of methylene glycol
CNS, CV, QT prolongation, RENAL effects (AKI, kidney stone)
effects of methanol
CNS and VISUAL (“snowstorm”)
where do you check sensation for L5 nerve root
first web space (between great/2nd toe)
how to treat PJP pneumonia
Bactrim. If A-a grad >35 or PaO2 < 70, add steroids.
treatment of tetanus disease
administer tetanus immune globulin, surgical wound debridement, abx, supportive care
fentanyl affects mu receptors and has what additional activity?
serotonergic
indication for HD in salicylate toxicity
pulmonary edema
unstable TdP: cardiovert or defib?
unstable but +pulse: cardiovert
only defib if pulseless
SCIWORA: risk factors, mechanism, location?
young age flex/extension mechanism #1 c spine
1 cause of cardiogenic shock
MI
mean incubation period for COVID-19
4-5 days
secondary gain vs volitional
secondary gain means there is something other than resolution of the primary health concern at play. Can be malingering or non-volitional such as in conversion disorder, where what is to be gained is avoidance of psychological stressor
mech of action of nitroprusside
venous/arteriolar smooth muscle relaxation –> afterload reduction
BP goal in acute ischemic stroke prior to tPA
SBP <185 and DBP <110
mech of action of tetanospasmin
inhibits release of glycine (CNS inhibitor neurotransmiter) producing involuntary muscle contractions
strychnine poison mech of action
antagonizes glycine (CNS inhibitory neurotransitter) receptors, which produce involuntary muscle contractions
child with exercise related syncope
think long QT, HOCM!
turner syndrome is associated with what vascular pathology
aortic dissection
how does esophageal web present
poor PO tolerance after introduction of solid foods
neonate 1-2 days with feeding difficulties and excessive drooling (not infectious)
think TE fistula
electrolyte disturbances in rhabdo
hyperK, hyperphos, hypOcalcemia
treatment of PD-related peritonitis
intraperitoneal vanc or first gen cephalosporin
toxic substance with natural gas + rotten egg smell
hydrogen sulfide
severe hydrogen sulfide toxicity symptoms?
CN-like toxicity
severe lactic acidosis, AKI, CNS, cardiac sx.
what to use against ESBL?
carbapenems
extended spectrum cephalosporin + betalactamase
ESBL has activity against beta lactams and aztreonam
sensitivity of NCHCT for SAH decreases with…
time, anemia, atypical presentation (isolated neck pain)
1 cause of large bowel obstruction
CRC
oleander poisoning
rapid GI sx, hyperK, dysrhythia (like dig)
pt presents with significant hyperthermia in setting of sympathomimetic use. What medication should be avoided?
antipsychotics: lower seizure threshold (can worsen hyperthermia)
first line prevention for cluster headaches
verapamil
niacin (B3) deficiency
pellagra:
photosensitive dermatitis, diarrhea, dementia
Westermark sign
decreased vascular markings (vascular cutoff sign)
sign of PE
Hamman sign
crunching sound heard over the mediastinum in the presence of mediastinal air
most sensitive Xray for free air
lateral CXR
fever, RLQ abd pain, diarrhea, normal appendix
Yersinia enterocolitica (mimics appy)
steps to acid-base
- acidosis vs alk
- AG = Na - Cl - bicarb (>20 = primary AG acidosis)
- EAG = AG + bicarb - 12 (>30 = metabolic alkalosis; <24 non-gap metabolic acidosis)
- compensation? PaCO2 should = decimals of pH
When to suspect CN toxicity?
burn + AG acidosis + lactate > 8
bradycardia, hypotension
best lab for epidural abscess
ESR
Maltese cross sign in urine
pathognomonic for nephrotic syndrome
UA with +blood but neg RBCs
myoglobinuria (think rhbado)
what dysrhythmia is associated with dig toxicity?
ANY, but make assoc with bidirectional VT and AF without RVR
preferred approach for knee arthrocentesis
anterolateral or superolateral
what voltage is high voltage?
~600 V (household 120 - 240 volts)
treatment for air embolism stroke
HBO
1 complication of hyphema
elevated IOP
most common life-threatening arrhythmia immediately following a lightning injury
asystole
Test of choice for GIB if endoscopy neg
CTA
treatmet for acute chest
O2, fluids, abx, pain control
PIP and DIP nodes: RA or OA?
OA (absence of DIP points towards RA)
HR for admission in anorexia
<50 awake / <45 asleep
+orthostatics (>20 bmp)
Temp for admit in anorexia
<35.56
BP for admit in anorexia
SBP<90
+orthostatics (+10 mm Hg)
weight for admit in anorexia
<75% IBW or losing weight despite therapy
strongest indications for HBO
syncope, CO-Hb >25% (or >20% in pregnancy), severe acidosis pH < 7.10, evidence of end organ damage
direct vs indirect inguinal hernia
indirect = in scrotum
Hill-Sachs vs Bankart
Hill-Sachs = on humeral head Bankart = on glenoid
how long does it take for molluscum contagiosum to resolve
months
clothes of sexual assault victims -> how to dispose?
paper bag and give to police
different drugs for thyroid storm
thionamide, iodine, BB, steroids
features of inflammatory back pain
subacute, nighttime pain, improvement with activity, no improvement with rest
staccato cough
chlamydia pnuemonia in children
1 tendon injury in athletes
mallet finger
how to splint mallet finger
in slight hyperextension at DIP, FROM at PIP
congestion, facial pain –> fever, HA + lateral gaze palsy. Dx?
cavernous sinus thrombosis
1 disease associated with anterior uveitis
ankylosing spondylitis
ratio of powdered baby formula to water
1 scoop to 2 ounces
how to tell difference between primary and secondary adrenal insufficiency
hyperK often seen in primary but never in secondary
what is a normal ABI
> 0.9
1 assoc injury with knee disloc
popliteal artery
toxic dose of ibuprofen
100 mg/kg
what is rubella?
mostly abroad due to vaccination, caused by togavirus, causes mild illness with rash, can cause congenital rubella
congenital rubella
cataracts, hearing loss, blueberry muffin rash
rash assoc with non-congenital rubella
pinpoint, erythematous, blanching macules that spread cephalocaudal
generalizes within 24 h and lasts for 3 d
what respiratory fluoroquinolones do not have good Pseudomonas coverage?
moxi, levoflox
intussusception = what belly exam?
sausage shaped mass in RUQ
pyloric stenosis = what belly exam?
olive shaped mass in upper abdomen
which maneuver is better for nursemaids?
hyperpronation > flexion/supination
encapsulated organisms
SHiNE SKiS Strep pneumo H. influenza Neisseria meningitis E coli Salmonella typhi Klebsiella pneuoniae Strep group B
1 most common lung cancer
adenocarcinoma
lung cancers centrally located
small cell
squamous cell
common contaminants in blood cultures
coag neg Staph, Bacillus, Propionibacterium
systemic JIA clinical
quotian (once daily) fever, arthritis, rash
why do nasal button batteries produce septal necrosis?
electrical current
most sensitive physical exam finding to exclude torsion
cremasteric reflex
dose of pediatric code epi
0.01 mg/kg 1:10,000
Parkland formula
4 cc * % BSA * kg in first 24 hrs
50% in first 8 hours, remainder over 16 hours
PPV/NPV vs LR+ / LR-
PPV/NPV are calculated based on disease prevalence and cannot be applied to populations outside the study population
LRs can be applied to pre-test probabilities to attain post test probabilities.
formula for LR+
sens / (1 - spec)
formula for LR-
(1 - sens) / spec
etanercept is what kind of medication
anti TNF (for AS, JIA, psoriasis, RA)
anti TNF produces what side effects
immune suppression
best way to prevent pediatric drowning
fence and latch (swim lessons not effective enough)
1 most common cause of death after resuscitation from hypothermia
pulmonary edema
1 cause of SBO in pregnancy
adhesions
time frame and mechanism of acute rejection in renal transplantation.
What cells involved?
within weeks of transplant.
CD8 mediated, type IV hypersensitivity
leukocyte infiltration to graft vessels impairing perfusion
Treatment of epididymitis
< 35 years OR high risk sexual behavior: CTX/doxy
> 35 years: levofloxacin (2nd line Bactrim)
diagnostic test for suspected Boerhaave syndrome
contrast esophagram
Reed sternberg cells have what appearance and are associated with what dx?
owl’s eye
Hodgkin lymphoma
treatment for hypercalcemia of malignancy
fluids +/- bisphosphonates / calcitonin
bilateral pedicle fracture of C2 is what fracture, and what is the mechanism of the fracture?
hangman fx, extension
farm/animal + atypical pneumonia
Q fever (Coxiella burnetii)
features of atopic dermatitis for clinical dx
flexor involvement, onset prior to age 2, hx atopy, intense itching
treatment for Jefferson fracture
halo
C1 burst fx, often football player or diver
phimosis vs paraphimosis
phimosis = foreskin cannot be retracted paraphimosis = foreskin cannot be extended
phimosis in Greek means “muzzle”
typhoid fever clinical picture
travel, GI sx, rash, bradycardia relative to fever
What anatomic structure delineates internal from external hemorrhoids?
dentate line
treatment for hypothermic arrest
ECMO / CPB
1 non-device related complication of LVAD pts
bleeding
what coagulation factors are NOT made in the liver?
factor VIII and vWF
how do you dose rhogam?
50 mcg for <12 weeks gestation
300 mcg for hemorrhage up to 30 cc’s
Kleihauer-Betke test if >30 cc’s is suspected (e.g. abruption at full term)
ddx of neonatal conjugated hyperbilirbinemia
sepsis, TORCH infection, biliary atresia, CF, inborn errors
1 cause of neonatal seizures
HIE
DDx for narrow complex PEA
tension, tamponade, PE, hypovolemia, ischemia
risk factors for PRES
HTN, renal failure, immune suppression, autoimmune disorders, pregnancy
clinical dx of carpal tunnel syndrome
Tinel and Phalen are neither sensitive nor specific.
Most sensitive is altered sensation at second finger pad