Abdominal Aortic Aneurysm Flashcards
What is size is considered aneurysmal
3.0cm
Abnormal levels of what haven been seen in degenerative AAA?
Metalloproteinases in the media
Deficits of antiproteolytic enzyme that inhibits metalloproteinase-1
Which conditions are related to inflammatory aneurysmal degeneration
Takayasu, GCA, PAN, Bechet, Cogan, Cystic Medial Necrosis
Examples of aneurysms associated with developmental abnormalities
Persistent sciatic artery
Kommerell diverticulum
AAA (Tuberous Sclerosis)
Connective Tissue Disorders related to AAA
Ehlers-Danlos (Collagen type III) Marfan, Loeys-Dietz
smoking history and AAA
Direct correlation between incidence and duration of smoking
Decreased aneurysm growth rate in association with duration of smoking cessation.
AAA rupture risk
3.0-3.9 = 0.3%
4.0-4.9 = 0.5-1.5%
5.0-5.9 = 1-11%
6.0-6.9 = 11-22%
>7 = >30%
Risk of AAA rupture is independently associated with what factors?
larger initial AAA diameter, current AAA size, smoking, lower FEV1, female
What is considered a fast growing AAA?
greater than or equal to 10mm within a 12mo period
Other indications for repair of AAA (besides size criteria)
saccular aneurysm, dissection of mural thrombus, fracture of saccular calcification
Advantage of endovascular vs open repair
equivalent at 2 years. Endovascular has significantly reduced early mortality and morbidity benefits
What are the 6 approved infrarenal stent-grafts?
Zenith (Cook) Aorfix (Lombard) Excluder (Gore) Endurant (Medtronic) AFX (Endologix) Ovation (Trivascular)
Predictors of perclose proglide failure?
Small access vessel diameter, anterior wall calcification (p. 912)
What size arteriotomy do you need to perform preclose technique and requires 2-suture when using the proglide device?
anything greater then 8 Fr
Factors that increase change of caudal migration of endograft
large angulation of the neck, short neck length, neck thrombosis, large neck diameter