Abdominal Flashcards
Risk factors for GORD?
Smoking, alcohol, hiatus hernia, pregnancy, obesity, nitrates, tricyclic antidepressants, acidic/fatty foods
Typical patient with GORD?
Obese man, retrosternal burning pain, worse on lying flat and after meals
Three major symptoms of GORD?
- Heart burn after eating/when lying, relieved by antacids
- Odynophagia
- Retrosternal burning
Two minor symptoms of GORD?
- Nocturnal cough
2. Morning hoarseness
Two investigations for GORD?
- Endoscopy
2. 24hr pH monitoring
Conservative treatment of GORD?
Reduce weight, cut down smoking, change diet
Four medical treatments of GORD?
Antacids
H2 receptor antagonists (ranitidine)
PPIs (omeprazole)
Prokinetics (metoclopramide)
Five complications of GORD?
Oesophagitis Oesophageal stricture Barrett's Ulceration Anaemia
Which sex is more likely to get peptic ulcer?
Men 2x more likely
Risk factors for peptic ulcer?
H. pylori (MOST COMMON) NSAIDs Smoking Stress Steroids
Typical patient with peptic ulcer?
Middle aged man, long-term epigastric pain, presents with melaena
Five symptoms of peptic ulcer?
Epigastric pain (worse at night/after food, relieved by antacids) Nausea/vomiting Haematemesis/melaena Weight loss Anaemia
Investigations for peptic ulcer?
H pylori screen (rapid urease/urea breath test)
Endoscopy
Conservative treatment of peptic ulcer?
Stop smoking/NSAIDS
Avoid foods that cause symptoms
Two treatments for peptic ulcer?
Acid suppression (PPIs, H2 receptor antagonists) H pylori triple therapy
Five complications of peptic ulcer?
Malignancy Haemorrhage (15-20%) Perforation Pyloric stenosis Anaemia
Who gets UC?
Age 15-30 yrs, more common in women and caucasians
Features of UC?
Insidious onset Diarrhoea with blood Distension Malaise, anorexia Severe colitis
Blood test changes in UC?
Low Hb
Raised CRP
Other investigations of UC?
Stool culture
Abdominal XR
Abdominal USS
Endoscopy with biopsy
Medical treatment of UC?
Mild: prednisolone, aminosalicylate
Severe: IV hydration, hydrocortisone, immunosuppression
Remission: Aminosalicylates, immunosuppression
Surgical treatment of UC?
Colectomy with ileostomy
Four complications of UC?
Perforation
Bleeding
Toxic megacolon
Colon cancer (30% after 35yrs)
Pathologic features of UC?
Continuous lesions
Ulcers
Goblet cell destruction
Crypt abscesses