Abdomen and Spleen Flashcards
What size particle is rapidly cleared in lymphatics
<10um
What rate does peritoneum absorb fluid
3-8% body weight/hr
What are consequences of acute abdominal compartment syndrome
- acute pulmonary failure to compressive atelectasis
- increased intrathoracic pressure leading to increased pleural/ pericardial pressure
- acute renal failure with marked oliguria
- intestinal ischemia with bacterial translocation
- hepatic ischemia
- decreased cerebral perfusion/ neuronal injury
- venous thrombosis/ thromboembolism
What % of primary peritonitis are monobacterial in dogs/ cats?
- Dogs- 53%
- Cats- 100%
What are risk factors for septic peritonitis (post GI surgery in Grimes 2011?
- Pre-operative septic peritonitis
- decreased albumin
- decreased protein
- intraoperative hypotension
What was a protective factor for septic peritonitis (post GI surgery in Grimes 2011)
presence of a foreign body
What are 2 most common bacteria found with septic peritonitis?
- E. coli
- Bacteroides fragilis
For septic peritonitis, what is the BG in chemistry usually? What is the B-F difference?
< 50mg/dL
- B-F >20mg/dL
For chylous peritoneal fluid, how do serum/ abdominal fluid compare?
Triglycerides fluid > 3X serum
Cholesterol fluid <serum
What is the recommended combination of antibiotics for septic peritonitis?
3rd generation cephalosporin or ampicillin and aminoglycoside
What is the recommended lavage amount?
200-300 ml/kg
What are different surgery methods to help prevent septic peritonitis?
-serosal patering?
- omentalization
- fibrin sealant
List 3 ways to manage continued effusion/ septic peritonitis post-op?
- Open peritoneal drainage
- Vacuum-assisted closure
- Closed peritoneal drainage
What is the downside of sump tube drainage?
Gives air vent to overcome vacuum phenomenon and allows airbone bacteria access to peritoneal cavity
What are the common complications of closed peritoneal drainage?
hypoprotenemia/ anemia
What has the literature suggested with epidurals and septic peritonitis cases?
- contraindicated and survival times
- decreased cardiac/ renal function from abdominal sympathetic blockade
What has been suggested with lidocaine?
When given intraop, improves survival.
When given post-op, survival odds are less.
What is the range of survival for septic peritonitis?
32-85% depending on the method of closure, drainage, etc.
Average ~50-60%
What are prognostic factors throughout VLT 67?? (sp?) that are associated with septic peritonitis?
- refractory hypotension
- CV collapse
- respiratory distress
- DIC
- pre-op Protein C > 60%
- TEG (?)
- Increased ALT/ GGT
- Lactate > 2.5
- Decreased Ca
- MODS
- Pre-op antithrombin > 41.5%
What is the most common bacteria in intra-abdominal abscesses?
Bacteroides fragilis
What is the difference between a fistula and a sinus tract?
Fistula- abnormal pathway between 2 anatomic spaces or path leading to internal cavity or organ to surface of the body (between 2 epithelial lined structures)
Sinus- abdominal channel that orignates or ends in one opening (mesothelium distinct from epithelium)
What is the prognosis for abdominal mesothelioma?
1 report for 42 months with surgery
List neoplasia differential diagnoses for hemic/ nonhemic spleen?
Hemic- lymphoid, mast cell, histiocytic, plasma cell
Nonhemic- hemangiosarcoma, sarcoma, benign of CT origin
What can be ascertained on AUS with splenic torsion?
Hilar perivenous hyperechoic triangle noted
What is the agreement between FNA/ histology for diagnosis?
- Complete 60%
- Partial 30%
- Disagreement 12%
What stain facilitates identification of cells of hemic origin?
Komanowsky
List options for partial splenectomy?
- TA stapler
- VSD
- Ultrasonic cutting device
- CO2 laser
- Bipolar cautery
- Suture ligation
What breeds most often get splenic torsions? Is there a sex predisposition?
- Great Dane, St. Bernards, GSD, Irish Setter
- Males> Females
What is the prognosis for a splenic torsion?
-Guarded to good with chronic torsions carrying a better prognosis (decreased incidence of cardiovascular shock/ toxemia)
What 3 breeds are overrepresented with splenic hemangiosarcoma?
GSD, Labrador, Golden retriever