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INFECTIOUS DISEASE 2019 > Ab Spectrum Quiz > Flashcards

Ab Spectrum Quiz Flashcards

1
Q

Penicillins

A

Penicillin V

Penicillin G

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2
Q

Coverage for Penicillins

A

Surfers hand Y
Streptococcus (Pyrogenes, Viridans &some Pneumo), Treponema palidium (SYPHILIS),
some staph

Enterococcus faecalis

Very little N. meningitidis

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3
Q

Drug of choice for Syphilis

A

Penicillin G

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4
Q

Antistaphylococal Penicillins

A

Nafcillin
Dicloxacillin

There is added protection here against beta-lactamases to enhance staphylococcal coverage

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5
Q

Antistaphylococcal Penicillins have coverage for…

A

BABY SHARK HAND
MSSA (Staph Aureus)
Staph epi
Streptococcus (S. pneumoniae, pyogenes)

NOT ACTIVE AGAINST MRSA, ENTEROCOCCI, ANAEROBES

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6
Q

Nafcillin

A

Nafcil

Antistaphylococcal Penicillin

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7
Q

AmiNOpenicillins

A

Ampicillin

Amoxicillin

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8
Q

Aminopenicillin coverage…

A

LEFT HAND L

E. faecalis
PCN resistant S. Pneumo
S. pyogenes

N. meningitidis
H. Influenzae

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9
Q

HEN PEKS

A 
H. Influenzae
Enterobacter aerogenes
N. meningitidis
Proteus mirabilis
E.Coli
Klebsiella
Serratia marcescens
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10
Q

Ampicillin is DOC for…

A

E. faecalis

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11
Q

Aminopenicillins are 1st line for…

A

Otitis media

and DOC for endocarditis prophylaxis

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12
Q

Aminopenicillins + Beta Lactamase Inhibitors are different from just Aminopenicillins because…

A

Gram Neg (HEN PEKS), with added Anaerobic coverage, and MSSA

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13
Q

Aminopenicillins +Beta Lactamase Inhibitors

A

Ampicillin/sulbactam

Amoxicillin/clavulanate

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14
Q

Amoxicillin/clavulanate Brand Name…

A

Augmentin

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15
Q

Ampicillin/sulbactam Brand name…

A

Unasyn

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16
Q

Aminopenicillins+Beta Lactamase Inhibitor coverage…

A 
HEN PEKS
Bacteroides fragilis
Staph aureus(MSSA)
S.Pneumoniae
S. Pyogenes
Enterococcus
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17
Q

Ampicillin/sulbactam is a great drug to tx..

A

Enterococcus

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18
Q

Piperacillin/Tazobactam Class

A

Antipseudomonal PCN + B lactamase inhibitor

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19
Q

Piperacillin/Tazobactam Brand

A

Zosyn

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20
Q

Piperacillin/Tazobactam coverage…

A

Covers everything except E. faecium & MRSA

PRIMARILY USED FOR PSEUDAMONAS

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21
Q

Really important Tx for MRSA…

A

Vancomycin

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22
Q

The ONLY Cephalosporin to cover MRSA…

A

Ceftaroline

TEFLARO

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23
Q

1st Generation Cephalosporins cover mostly…

A

Gram Positives

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24
Q

2nd Gen Cephs cover mostly…

A

GPs with few GNs

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25
Q

3rd Gen Cephs cover..

A

Mainly GNs

Ceftazidime covers Pseudos

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26
Q

4th Gen Cephs cover…

A

Mainly GNs

Cefepime covers Pseudos

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27
Q

1st Generation Cephalosporins…

A

Cefazolin
Cephalexin
Cefadroxil

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28
Q

1st gen Ceph coverage….

A

MSSA
Staph
Strep

Very little coverage:
Proteus
E. Coli
Klebsiella

3 fingers

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29
Q

Cefazolin is mostly used for….

A

Pre-Op Prophylaxis

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30
Q

2nd Generation Cephs…

A 
Cefuroxime
Cefoxitin
Cefotetan
Cefprozil
Cefaclor
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31
Q

2nd gen cephs that have activity against Anaerobes..

A

Cefotetan
Cefoxitin are both active against B.fragilis

TAN FOX**

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32
Q

2nd Gen Cephs “Claim to Fame”

A

H. Influenza

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33
Q

Coverage of 2nd Gen Cephs…

A 
4 finger
S. pyogenes
S. Pneumoniaa
MSSA
H.Influenza
N. Meningitidis
P. mirabilis
E. coli
Klebsiella spp.
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34
Q

2nd Gen TAN FOX coverage…

A

5 fingers

Expanded to include Anaerobe–> B. fragilis

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35
Q

Cefotetan Brand Name and Class…

A

Cefotan

2nd gen ceph

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36
Q

Cefoxitin Brand name and Class…

A

Mefoxin

2nd gen ceph

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37
Q

3rd Gen Cephs…

A

Cefotaxime
Ceftriaxone
Ceftazidime
Ceftazidime/Avibactam

Cefixime
Ceftibuten
Cefditoren
Cefpodoxime
Cefdinir
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38
Q

3rd Gen Ceph coverage…

A 
5 fingers
S.Pneumoniae
S. Pyogenes
MSSA
Enterobacter spp
H. influenza
N. meningitidis
Proteus mirabilis
E.coli
Klebsiella
Serratia
39
Q

Ceftriaxone Brand and class…

A

Rocephin
3rd gen ceph

Good BBB tx for meningitis

40
Q

Ceftazidime Brand and class…

A

Fortaz

  • Different from the other 3rd gens because it covers Pseudomonas
  • Very little GPC
41
Q

CAPES Bacteria

A 
Citrobacter
Acinetobacter
Pseudomonas
Enterobactr
Serratia
42
Q

Ceftazidime/avibactam coverage…

A

Pseudomonas
CAPES
-Loses most of GPC

3rd gen ceph

Ceftazidime ALONE is good for Pseudomonas as well

43
Q

Ceftriaxone is DOC for..

A

gonorrhea

44
Q

4th generation Cephs…

A

Cefepime

45
Q

Cefepime coverage…

A

5 fingers, no faecalis, no MRSA, no anaerobes

Streps, 
MSSA, 
PEKS, 
N.Meningitidis, 
H.influenza, 
Enterobacter spp
Pseudomonas
CAPES
*Acinetobacter*
46
Q

5th gen cephs…

A

Ceftaroline

Ceftolozan/Tazobactam

47
Q

Ceftaroline Brand…

A

Teflaro

48
Q

Ceftolozan/Tazobactam Brand…

A

Zerbaxa

49
Q

Ceftaroline coverage…

A

5 finger
Including MRSA
Not including Faecalis

50
Q

Ceftolozane/tazobactam coverage…

A

Strep
PSEUDOMONAS
And more

51
Q

Which Cephs cover Pseudomonas??

A

CeftaziDIME
CeftaziDIME/avibactam
CefePIME
CeftoloZANE (w/or w/o Tazobacatm)

52
Q

Monobactam class contain..

A

Aztreonam

53
Q

Monobactams coverage…

A

NO GPC
All GN, including Pseudo

HENPEKS & Pseudo

54
Q

Carbapenems…

A

Impinem/cilastatin
Ertapenem
Meropenem
Meropenem/Vabobactam

55
Q

Carbapenems coverage…

A

6 fingers!

NO MRSA

56
Q

All carbapenems have Pseudo coverage except…

A

Ertapenem

57
Q

Carbapenems cover SO much but they don’t include

A

VRE, MRSA, or LMC

58
Q

Ertapenem is different from the others in its class because it doesn’t cover…

A

E. faecalis, or Pseudo

59
Q

Vancomycin class & brand…

A

Glycopeptide

VANCOCIN

60
Q

Vancomycin coverage..

A 
ALL GPC
Especially Staph (MRSA)
Strep
Enterococci
Corynebacterium
C. Difficile
61
Q

Telavancin class and brand…

A

Lipoglycopeptide

VIBATIV

62
Q

Telavancin coverage…

A

MSSA
MRSA
Strep
Vanco-resistance F. faecalis

63
Q

Daptomycin class and brand…

A

Cyclic Lipopeptide

CUBICIN

64
Q

Dapto coverage…

A

GPC
Staph (MRSA AND VRSA)
Entercoccie INCLUDING FAECALIS AND FAECIUM

Doesn’t treat Pneumonia

65
Q

Class that has really good AtYpical coverage…

A

Macrolides

Erythromycin
Clarithromycin
Azithromycin
Fidaxomicin

66
Q

Oral macrolide for C.diff ONLY

A

Fidaxomicin

DIFICID

67
Q

Macrolide coverage…

A 
MSSA
S. Pneumoniae
S. viridans &pyogenes
Listeria
Haemophilus
H. flu
M.catarrhalis
Bordetella
Neisseria
Shigella

IMPORTANT
Legionella
Chamydia
Mycoplasma

68
Q

Azithromycin Brand

A

Zithromax

Macrolide

69
Q

Clarithromycin

A

Biaxin

Macrolide

70
Q

Erythromycin

A

E.E.S

Macrolide

71
Q

Aminoglycosides…

A 
Amikacin
Tobramycin
Gentamicin
Streptomycin
Neomycin
Plazomicin
72
Q

Aminoglycoside coverage…

A 
Gram+
Staph
Gram- 
Pseudo
Proteus
Serratia
73
Q

Tetracyclines…

A

Tetracycline
Doxycycline
Minocycline

74
Q

Minocycline brand and coverage info….

A

Minocin

DOC CA-MRSA

75
Q

Tetracycline coverage…

A 
MSSA
Strep
Enterococci
Nocardia
Bacillus
Propionibacterium

haemophilus
Moraxella
chlamydia

ATYPICALS
Spirochetes
Rickettsiae
Bacillus anthracis
Treponema pallidum
76
Q

Glycyclcline coverage…

A 
BROAD
Most streps
MSSA
MRSA*
VRE

H.flu
Klebsiella

Clostridium
Bacteroides

Chlamydia
Legionella
Mycoplasma

77
Q

Oxazolidinone class

A

Linezolid

Tezolid

78
Q

Linezolid & Tezolid coverage…

A

Similar to Vanc

MRSA**
S pneumo
VRE*

79
Q

Quinolones class

A

Ciprofloxacin
Levofloxacin
Moxifloxacin

80
Q

Quinolones coverage….

A

E faecalis
Strep
MSSA
Listeria

H. flu
Moraxella
Neisseria
PSEUDO

Chlamydia
Legionella
Mycoplasma

81
Q

Quinolones with enhanced activtiy against strep pneumo and atypicals….

A

Moxi
Gemi
Levo

82
Q

Quinolone for MRSA

A

Delafloxacin

83
Q

Important sulfonamide

A

Sulfamethoxazole/trimethoprim

84
Q

Sulfamethoxazole/trimethoprim brand

A

Bactrim

85
Q

Bactrim coverage…

A 
Most GPC
MRSA
CA-MRSA
Strep no GAS
Listeria
Nocardia
Stenotrophomonas
Haemophilus
Proteus
E.coli
Klebsiella
Enterobacter
Shigella
Salmonella

Toxoplasmosis parasite

86
Q

Important Lincosamide..

A

CLINDAMYCIN

87
Q

Clindamycin coverage…

A

Strep & Staph
CA-MRSA

Anaerobes like B FRAGILIS*

88
Q

Clindamycin brand name

A

Cleocin

89
Q

Metronidazole mainly covers..

A

C. Diff

Protozoa (giardiasis, gardnerella, amebiasis, trichomonas)

90
Q

Fidaxomicin

A

Dificid

91
Q

Approved tx for C. Difficile

A

Dificid

92
Q

Nitrofurantoin description

A

Urinary Antiseptic

ONLY for lower UTI tx

93
Q

Nitrofurantoin coverage…

A

S. aureus
Enterococcus VRE

E. coli
Klebsielle
Enterobacter

INFECTIOUS DISEASE 2019 (1 decks)

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