AAMC FL 2 Flashcards

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1
Q

Which amino acid’s side chain is frequently encountered at the active site of metalloenzymes?

A

Histidine. Active sites of metalloenzymes resemble the five-membered imidazole rings associated with histidine.

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2
Q

Absorption of ultraviolet light by organic molecules always results in what process?

A

Excitation of bound electrons

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3
Q

Increasing the polarity of the eluting molecule will increase its affinity for the stationary phase and (increase or decrease) the elution time?

A

Increase the elution time. Decreased retention factor.

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4
Q

The half-life of a radioactive material is the time it takes for half of all the radioactive nuclei to decay into (daughter or radioactive) nuclei?

A

Daughter nuclei which may or not also be radioactive.

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5
Q

Why must the person either lean forward or slide their feet under the chair in order to stand up?

A

To keep the body in equilibrium while rising

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6
Q

Aromatic side chains absorb in the near UV region of the electromagnetic spectrum, which has longer wavelengths, and hence lower energy, than peptide bonds.

A

Aromatic side chain has more closely spaced energy levels.

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7
Q

What type of curves indicate cooperative processes?

A

Sigmoidal curves (S-shaped)

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8
Q

A decrease in oxidation number is a reduction or an oxidation?

A

Reduction

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9
Q

G-C base pairs form (stronger or weaker) pi-stacking interactions than A-T base pairs.

A

Stronger. Most thermal stability. Increase in melting temperature in GC-rich DNA

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10
Q

The lone pair of electrons in ammonia allows the molecule to act as a Lewis (acid or base) in water.

A

Lewis base that donates the electron pair in forming a covalent interaction.

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11
Q

When K is greater than 1,

A

the reaction’s deltaG is negative and the reaction is spontaneous.

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12
Q

The Lewis acid-base interaction between a metal cation and an electron pair done is known as a ___ bond?

A

Coordinate covalent bond

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13
Q

In DNA, sugar-phosphate backbones form the (interior or exterior) of the double helix.

A

Exterior

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14
Q

Bonds between identical atoms are likely to be the (least or most) polar ?

A

Least polar

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15
Q

Negative focal length = diverging lens. What type of image do it form?

A

Virtual and reduced images of objects situated at distances larger than the focal length.

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16
Q

Protein secondary structure is represented by repeated patterns of hydrogen bond between

A

the backbone amide protons and carbonyl oxygen atoms.

17
Q

Ubiquitination targets a protein for ____ by a proteasome.

A

Degradation

18
Q

Posttranslational modification of proteins such as histone acetylation is analyzed by what type of blotting?

A

Western blotting (SNOW DROP)

19
Q

The brain is derived from what germ layer?

A

Ectoderm (central nervous system)

20
Q

The tips of an antibody are the what type of regions?

A

The variable regions (specific for a particular antigen)

21
Q

Dependency ratio

A

The number of economically dependent members of the population (too young or too old) to the number of economically productive members (working-age 16-85)