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AAB MT Generalist Exam Review > AAB Multiple Choice Questions > Flashcards

AAB Multiple Choice Questions Flashcards

1
Q

Give the formula for weight (in grams) of substance in a given quantity of solution (e.g. the weight of NaCl in 650mL of 0.85% solution).

A

(total mL / 100mL) * (% concentration)

For the example: 5.53g NaCl

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2
Q

Which of the following assays is commonly used to confirm the diagnosis of Activated Protein C resistance?

Factor V Leiden Mutation Assay
Antithrombin Activity Assay
Antithrombin Antigen Assay
Anticardiolipin Antibody Immunoassay

A

*Factor V Leiden Mutation Assay

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3
Q

Many laboratories use the Factor V Leiden Mutation assay to confirm the diagnosis of Activated __ __ resistance.

A

Protein C

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4
Q

The Factor V Leiden Mutation assay is a molecular assay used to determine all of the following EXCEPT:
A. zygosity
B. predict the risk of clotting
C. antithrombin activity
D. Form a treatment plan for Activated Protein C resistance.

A

C. antithrombin activity

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5
Q

T or F: The antithrombin activity assay and the antithrombin antigen assay are both used to assess antithrombin levels and activity.

A

True

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6
Q

The anticardiolipin antibody immunoassay is useful in the detection and diagnosis of __ syndromes.

A

antiphospholipid

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7
Q

Increased concentration of alpha-fetoprotein (AFP) in adults are most characteristically associated with:

A. Hepatocellular carcinoma
B. Alcoholic cirrhosis
C. Both A & B
D. Multiple myeloma

A

A. Hepatocellular carcinoma

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8
Q

alpha-fetoprotein (AFP) is one of the __ proteins which are produced in high concentration during fetal life. AFP is produced by the fetal __ __ and __. Oncofetal proteins usually disappear or are reduced to very low concentrations after __.

A

oncofetal

yolk sac; liver

birth

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9
Q

Mucopolysaccharidosis is a group of inherited enzyme deficiency disorders that lead to which of the following WBC inclusion bodies:

A. Toxic granulation
B. Dole bodies
C. Alder-Reilly bodies
D. May Hegglin

A

C. Alder-Reilly bodies

Alder-Reilly bodies may resemble heavy toxic granulation, but they can appear on lymps and monos, not just neutrophils.

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10
Q

Dole bodies are a gray-blue neutrophil cytoplasmic inclusion composed of:
A. dsDNA
B. rRNA
C. mRNA
D. ssDNA

A

B. rRNA (ribosomal)

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11
Q

The presence of Dole bodies can be due to many factors EXCEPT:
A. birth control
B. bacterial infection / sepsis
C. physical stressors
D. pregnancy

A

A. birth control

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12
Q

What is the BEST type of microscopy for performing manual platelet counts?

A. Electron
B. Dark-field
C. Light
D. Phase contrast

A

D. Phase contrast

(can help to better define the outline of the platelets over regular light microscopy, making them easier to count)

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13
Q

Dark-field microscopy has the light source blocked, causing light to scatter as it hits the specimen. Therefore, it is often used for __ elements and allows illumination of the specimen against a dark background.

A

refractive

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14
Q

Tumor markers are especially valuable when used to:

A. Rule out cancer
B. Screen the general population for cancer
C. Monitor response to cancer therapy
D. Both A & C

A

C. Monitor response to cancer therapy

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15
Q

What is the purpose of using alcohol in the Gram stain procedure?

A. Fix all Gram-positive organisms
B. Decolorize all Gram-positive organisms
C. Decolorize all Gram-negative organisms
D. Fix all Gram-negative organisms

A

C. Decolorize all Gram-negative organisms

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16
Q

Gram-__ organisms have a thick peptidoglycan layer and therefore will trap the crystal violet/iodine mordent complex and will not decolorize.

Gram-__ organisms have a have a single peptidoglycan layer and an outer lipid layer and therefore will decolorize.

A

positive

negative

17
Q

Which of the following tests is the BEST screening test for neural tube defects?

A. Placental lactogen
B. Bilirubin
C. Estriol
D. Alpha-fetoprotein

A

D. Alpha-fetoprotein

18
Q

Alpha-fetoprotein is produced by the fetal __.

It is measured in pregnant women using:
A. maternal blood
B. Fetal blood
C. amniotic fluid
D. Both A and C

A

liver

D. Both A and C

19
Q

Abnormally high levels of Alpha-fetoprotein (AFP) in the developing fetus is associated with:
A. neural tube
B. liver defects

Abnormally low levels are associated with:
C. Down’ syndrome
D. megalencephaly

A

A. neural tube

D. megalencephaly

20
Q

All of the following organisms have been linked to causing endocarditis EXCEPT?

A. Aggregatibacter aphrophilus
B. Cardiobacterium hominis
C. Eikenella corrodens
D. Hemophilus influenzae

A

D. Hemophilus influenzae

21
Q

Organisms that are members of the HACEK [Aggregatibacter (Haemophilus) aphrophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae] group have been linked to causing:
A. pneumonia
B. endocarditis
All of the HACEK organisms are considered fastidious organisms and grow best on:
A. chocolate agar incubated in an increased CO2 environment
B. MacConkey agar incubated at 40-42℃

A

B. endocarditis

A. chocolate agar incubated in an increased CO2 environment

22
Q

What section of an immunoglobulin molecule is responsible for the differences between immunoglobulin classes?

A. FC
B. Fab
C. Heavy chains
D. Light chains

A

C. Heavy chains

23
Q

Antibodies are differentiated based on their __ chains; different heavy chains create different __.

A

heavy;
isotypes

24
Q

The Fc portion has a…
A. constant
b. variable
…amino acid sequence that defines the class and subclass of each antibody.

A

A. constant

25
Q

Depending on the class of antibody, some of the functional activities of the Fc portion of antibodies include:
A. activating the complement pathway
B. binding to natural killer cells
C. class differentiation only
D. Both A & B

A

D. Both A & B

26
Q

The __ section of an immunoglobulin molecule is the antigen-specific region.
A. Fc
B. Light chains
C. Fab
D. Heavy chains

A

C. Fab

27
Q

The Fab portion of immunoglobulin consists of the following EXCEPT:
A. Two light chains; portions of two heavy chains; and a variable region.
B. Two light chains and a variable region.
C. Two light chains (kappa and lambda), a variable region, and two free light chains (FLC) that has two antigen-combining sites at the N-terminal ends

A

A. Two light chains; portions of two heavy chains; and a variable region.

28
Q

True or false: Free light chains (FLCs) are incorporated into immunoglobulin molecules during T-lymphocyte development and expressed initially on the surface of immature T lymphocytes.

A

False:
Free light chains (FLCs)are incorporated into immunoglobulin molecules during B-lymphocyte development and expressed initially on the surface of immature B lymphocytes.

29
Q

What is the formula to calculate budget?

A

% Over Budget = ((Actual Expenses - Budgeted Amount)/Budgeted Amount) × 100

30
Q

What is the maximum number of white blood cells that may be present in 95% apheresis platelet units that have been leukocyte-reduced?

A. 1.0 × 10^10
B. 3.0 × 10^11
C. 5.0 × 10^6
D. 5.5 x 10^10

A

C. 5.0 × 10^6

31
Q

A unit of apheresis platelets must contain at least __ x 10^__ or more platelets in 90% of the units tested.
A. 1.0 × 10^10
B. 3.0 × 10^11
C. 5.0 × 10^6
D. 5.5 x 10^10

A

B. 3.0 × 10^11

32
Q

A unit of platelets must contain at least __ x 10^__ platelets or more in 90% of the units tested.
A. 1.0 × 10^10
B. 3.0 × 10^11
C. 5.0 × 10^6
D. 5.5 x 10^10

A

D. 5.5 x 10^10

AAB MT Generalist Exam Review (1 decks)

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