AA degradation and synthesis

Question 1

ketogenic AAs

Answer 1

{LLs - Liver}

Leucine
Lysine

Question 2

BOTH glucogenic and ketogenic AAs

Answer 2

{Fear I Tripped a Tiger}

Phenylalanine
Isoleucine
Tryptophan
Tyrosine

Question 3

glucogenic AAs

Answer 3

{Glucogenic GAGA CAMP HAS TV)

Glutamate

Glycinew
Asparagine
Glutamine
Aspartate

Cysteine
Arginine
Methionine
Proline

Histidine
Alanine
Serine

Threonine
Valine

Question 4

9 essential AAs

Answer 4

{Lucy & Val’s Meth Trip Is Like 3 Fucking Hours}

Leucine
Valine
Methionine
Tryptophan

Isoleucine
Lysine

Threonine
Phenylalanine
Histidine

+ Arginine** only “conditionally essential”

Question 5

what 3 sources is the amino acid pool supplied by?

Answer 5

dietary intake
protein degradation
de novo amino acid synthesis

Question 6

what do glucogenic AAs do that ketogenic AAs DO NOT do?

Answer 6

add extra carbons to the TCA cycle

Question 7

what are the two destinations for carbon skeletons of ketogenic AAs?

Answer 7

converted to Acetyl-CoA
-> enters ketogenesis, FA synthesis, or TCA

converted to acetoacetate
(a ketone body)
-> is oxidized in tissues capable of ketolysis
(NOT liver)

Question 8

AAs that enter TCA as OAA

Answer 8

Asn
Asp

Question 9

AAs that enter TCA as pyruvate

Answer 9

{at the “Pyr”, Alan Catches a Glimpse of 3 Trapped Seals}

Ala
Cys
Gly
Thr
Trp
Ser

Question 10

AAs that enter TCA as alpha-KG

Answer 10

{Professional Hot Glue Gun Art}

Pro
His
Glu
Gln
Arg

Question 11

AAs that enter TCA as fumarate

Answer 11

{Fuming Tigers}

Phe
Tyr

Question 12

AAs that enter TCA as succinyl-CoA

Answer 12

{it succs: Val Met 3 Izzys}

Val
Met
Thr
Ile

Question 13

which AA’s carbon skeleton is converted to Acetyl-CoA?

Answer 13

Ile

Question 14

AAs whose carbon skeletons are converted to acetoacetate

Answer 14

{La La, Fucking Tripped Tigers}

Leu
Lys
Phe
Trp
Tyr