A&P Lecture Exam Flashcards
Cells in epidermis (deep to surface)
- Stratum basale
- Stratum spinosum
- Stratum granulosum
- Stratum lucidum
- Stratum corneum
Merkel cells
Detect touch
Langerhan cells
Detect bacteria
Stem cells
Produce new cells by mitosis
Keratinocytes
Stack for protection
Melanocytes
Contribute to color
Process of keratinization
- Stem cells in stratum basale layer produce keratinocytes by mitosis
2.Keratinocytes get pushed upwards towards surface of skin - keratinocytes reach stratum granolusum
- Keratinocytes stack on surface of skin forming stratum corneum
Function of melanin
Protection from uv radiation
What affects the amount of melanin produced?
Genetics, hormones, exposure to uv light
Erythema (red)
Increase blood flow. Anger/Embarrass
Pallor (White)
Decreased blood flow. Anemia/stress
Cyanosis (Blue)
Decrease oxygen. Cold/Heart attack
Pathologic Jaundice (Adults)
Liver cant keep up with break down of biliruben
Physiologic Jaundice (Infants)
Liver not functioning yet
Main functions of your skin
- Sensation
- Excretion
- Protection
- Temperature regulation
- Vitamin D synthesis
How does each of these skin cellls/special features protect you
A. Keratin in keratinocytes - Overlap/provide barrier against water & chemicals
B. Acidic and salty sweat - Decreases fungus & bacteria
C. Melanin and melanocytes - Protection from uv light
D. Dryness - Decreases fungus & bacteria
E. Stratification - Stacking of keratinocytes in stratum corneum/prevent microbes from entering body
Vasoconstriction
Shut down flow of blood near skin surface
Vasodilation
Increased blood flow near skin surface, increasing heat loss
Good things Vitamin D does for us
- Works with calcium to from strong, dense bones
- Turns off cancer causing genes
- Decreases risk of multiple sclerosis
What can you do to make sure you have enough Vitamin D
- Take supplements
- Eat food rich in vitamin D
- Spend time outdoors
Pros of sunlight
- Make more Vitamin D
- Increase melanin production
- Increase UV light protection
Cons of sunlight
- Increade risk of skin cancer
- Age more rapidly
What causes acne?
Bacteria
ABCDE rule
A - asymmetry
B - border irregularity
C - color
D - diameter
E - evolving
3 types of burns
Superficial burns - no scarring
Partial thickness burns - possible scarring
Full thickness burns - has scarring
Serious issues associated with full thickness burns
- Dehydration/loss of bodily fluids requires continual IV’s
- Infection/loss of protective barrier
- Circulatory shock/cardiac arrest are main causes of death in burn victims
5 functions of skeletal system
- Support
- Protection
- Movement
- Storage
- Production of blood cells
3 close association headline cartilage has with bone
- Precursor for most bones in body during development
- Responsible for bone lengthening and repair
- Covers ends of long bones - articular cartilage
2 major types of bone cells
Osteoblasts - create new bone cells and bone tissue
Osteoclasts - break down bone tissue
Intramembranous ossification
A. 5th week fetal development, membrane forms around brain
B. Osteochondral progenitor cells produce osteoblasts
C. Osteoblast produce calcium/phosphate
D. Ossification centers expand outward
E. By age 2 skull bone complete
Endochondral ossification
A. 8th week fetal development, osteochondral progenitor cells produce chondroblasts
B. Chondroblasts make headline cartilage model of future bone
C. Primary ossification center begins in diaphysis-osteoblastsvstart making bone
D. Diaphysis is hollowed out, filled w red bone
E. Secondary ossification centers develop in epiphyses
Bone elongation
Chondrocytes in epiphyseal plate multiply, get larger, calcify & convert to osteoblasts
Effects of hypocalcemia
- Increase osteoblast activity/promotes bone resorption
- Inhibits osteoblasts activity
- Increase C++ resorption from kidneys
- Increase vitamin D formation
3 classification of joints by function
- synathroses- nonmovable- suture
- amphiarthroses- slightly movable- between body of 2 vertebrae
- diarthroses- freely movable- hip joint
3 classifications of joints by structure
- fibrous
- cartilaginous
- synovial
know 4 things that lead to osteoporosis
- smoking
- not enough exercise
- poor diet in calcium
- genetically petite