A&P Final Flashcards
Between the nervous and endocrine system what one is known for fast communication?
Nervous
What system has long lasting effects?
Endocrine
In the endocrine system how do messengers move?
Through blood and/or interstitial fluid
The impulses of the nervous system are conducted along what structure?
Axons
The nervous system uses chemical compounds to send signals and communicate. What are they called?
Neurotransmitters
What part of the endocrine system usually works in a cascade effect?
Hormones
Name the two different classes of glands.
Exocrine and Endocrine
What type of glands secretes material through ducts onto the surfaces both internal and external?
Exocrine
List some names/types of exocrine glands
sweat, oil, mucous, salivary, pancreas, live, etc
What gland type can perform multiple functions?
Endocrine
The pituitary, thyroid, hypothalamus, gonads, pancreas, liver, and adipocytes are what type of gland?
Endocrine
What gland type secretes directly into IF
Endocrine
Pineal and parathyroid are what type of gland?
Endocrine
What happens during down-regulation of hormones?
When too much hormone is present, receptors are destroyed. Controls how much hormone gets into the cell.
When too little hormone is present, and more receptors are made this is an example of what type of regulation?
Up regulation
What is the term for the driving force of hormone action and what does it mean?
Specificity - hormones only bind to target cells that have the specific protein receptor for that hormone.
- Lock and key mechanism
T or F
Receptors are very rarely being broken down and remade be the cell.
False - constantly!
There are two main categories of hormones. What are they?
Local hormones
Circulating hormones
An aka for circulating hormones is
Endocrine
How do circulating hormones work?
Secreted in the IF
Picked up by the blood and circulated throughout the body.
Travel far away from secretory cell.
What cells can circulating hormones act on?
Any cell along the way that has a receptor for it.
What are the two types of Local hormones?
Paracrine - acts on neighbouring cells
Autocrine - acts on secretory cell
Hormones can either be ______ soluble or _______ soluble.
Lipid or Water
What are lipid soluble hormones bound to for transport?
Transport protein
Can lipid soluble hormones diffuse through the cell membrane and why?
Yes because cell membrane is a phospholipid bilayer.
What is the mechanism of action of a lipid soluble hormone?
Enters target cell and goes to nucleus
Alters gene expression causing new protein synthesis thus alters cell activity
How does water soluble hormones circulate in the blood?
Without a transport protein
Describe the mechanism of the messenger systems of water-soluble hormones
1st messenger binds to receptor on plasma membrane which activates second messenger (cAMP) cascade inside the cell.
2nd messenger activates enzymes to produce physiological response.
The responsiveness of a target cell depends on what factors?
- Hormone concentration
- Abundance of receptors
- Influence of other hormones
Describe what triggers hormone secretions
Signals from nervous system
Chemical changes in the blood
Presence of other hormones
Most hormones operate by what kind of feedback loop?
Negative
List the primary organs of the endocrine system
Hypothalamus Pituitary Gland Thyroid Parathyroid Adrenals Pancreas Gonads Pinal Thymus
What organs are responsible for the secretion of estrogen and testosterone
Gonads - Ovary and Testis
What gland secretes Calcitonin?
Thyroid
Epinephrine and Norepinephrin are secreted by what gland?
Adrenal
List the secondary endocrine organs
Stomach, small intestine, kidneys, heart, liver, placenta, adipose tissue.
What hormone is associated with the placenta?
hCG
Leptin is associated with what secondary endocrine organ?
Adipose tissue
Calcitriol and erythropoietin are secreted by what organ?
Kidneys
What are the three main functions of blood?
Transport
Homeostasis: pH, body temperature, ion concentration
Protection: clotting, WBC, blood proteins
What is the pH range of blood?
7.35-7.45 slightly alkaline
Blood makes up what percent of total body mass?
8%
The average volume of blood in an adult is how many L?
5L
males: 5-6L
females: 4-5L
Plasma makes up what percentage of blood?
55%
The buffy white coat is composed of what blood elements?
Leukocytes & platelets
What blood elements represents 45% of total blood?
Formed elements - 99% of which are Erythrocytes
91.5% of plasma is ________
water
List three different types of plasma proteins
- Albumins - smallest and most numerous
- Globulins
- Fibrinogens
What percent of the plasma solutes are proteins?
7%
The blood protein responsible for transport of proteins is?
Albumins
What is the function of Globulins in blood?
Part of antibodies