A&P Cardiovascular system Flashcards

1
Q

Ventolin

A

Salbutamol, also known as albuterol and marketed as Ventolin, is a medication that opens up the medium and large airways in the lungs.

It is used to treat asthma, including asthma attacks, exercise-induced bronchoconstriction, and chronic obstructive pulmonary disease.

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2
Q

Thiazide

A

Thiazides are used to relieve oedema due to chronic heart failure and, in lower doses, to reduce blood pressure.

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3
Q

Seretide Accuhaler

A

Breath-actuated dry powder inhalers. Regular treatment of asthma where long acting β2-agonist and inhaled corticosteroid is appropriate.

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4
Q

Ischaemic changes in the brain

A

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. This leads to poor oxygen supply or cerebral hypoxia and thus to the death of brain tissue or cerebral infarction / ischemic stroke.

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5
Q

Thrombosis

A

the formation of a blood clot within a blood vessel. The clot may block the blood vessel and prevent or reduce the flow of blood, which can cause serious health consequences.

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6
Q

Endovascular mechanical thrombectomy

A

a treatment for stroke that removes clots that block large blood vessels. Some patients may be candidates for this procedure using an angiogram or a catheterization and a device that grabs clots and removes them, to re-establish blood flow to the brain.

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7
Q

Infarction

A

obstruction of the blood supply to an organ or region of tissue, typically by a thrombus or embolus, causing local death of the tissue

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8
Q

Stroke

A

a medical condition in which poor blood flow to the brain results in cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both result in parts of the brain not functioning properly.

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9
Q

Transient ischaemic attacks (TIAs)

A

mini-strokes, happen when there is a brief reduction in blood supply to part of the brain causing symptoms, such as temporary speech loss. A single occurrence doesn’t cause permanent damage to your brain and the symptoms usually pass within 24 hours. A person may have several TIAs over time, which means different parts of the brain can be affected

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10
Q

Broadmann areas

A

Originally defined and numbered into 52 regions

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11
Q

Brodmann Areas 1, 2, 3

A

Primary somatosensory cortex (postcentral gyrus) localization of touch, temperature, vibration, pain skilled and coordinated orofacial movement (i.e. whistling) (agraphesthesia, asterognosia, loss of vibration, proprioception and fine touch)

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12
Q

Brodmann Area 4

A

Primary motor cortex (precentral gyrus) It is responsible for executing motor movements, which includes contralateral finger/hand/wrist or orofacial movements, learned motor sequences, breathing control, and voluntary blinking. (paralysis of the contralateral side of the body, including facial palsy, arm or leg monoparesis, and hemiparesis.)

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13
Q

Brodmann Area 5

A

Somatosensory association cortex Processing chaotic patterns, using spatial imagery in deductive reasoning, motor execution, bimanual manipulation, working memory, language processing, pain perception, tactile localization, saccadic eye movement (ideomotor apraxia, which is the loss of ability to produce purposeful, skilled movements as a result of brain pathology, Astereognosis is also possible, which would lead to loss of ability to recognize objects by feeling or handling them.)

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14
Q

Brodmann Area 6

A

Premotor and supplementary motor cortex - this region is critical for the sensory guidance of movement and control of proximal and trunk muscles, and contributes to the planning of complex and coordinated motor movements. This area plays a large role in motor, language, and memory functions (result in kinetic apraxia (which would appear as coarse or unrefined movements that no longer have the appearance of being practiced over time)

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15
Q

Brodmann Area 9

A

Dorsolateral/anterior prefrontal cortex (motor planning, and organization) - This region is the highest cortical area responsible for motor planning, organization, and regulation, and sustaining attention and working memory. (problems with affect, social judgement, executive memory, abstract thinking, and intentionality.)

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16
Q

Brodmann Area 10

A

Anterior prefrontal cortex (memory retrieval) - involved in strategic processes of memory retrieval and executive functions (similar issues to area 9)

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17
Q

Brodmann Area 17

A

Primary visual cortex - the visual cortex is located in the occipital lobe in the back of the brain, and contains a well-defined map of the spatial information required for vision. (partial or complete cortical blindness can result)

18
Q

Brodmann Area 22

A

Primary auditory cortex - Primary auditory cortex / Superior Temporal Gyrus (part of Wernicke’s area) – this region is situated close to the external ear and involves complex language and auditory processing. (difficulty finding words, prosopagnosia (the acquired inability to recognize faces), disturbances in drawing)

19
Q

Brodmann Area 37

A

Occipitotemporal (fusiform) gyrus - processing of color information, face and body recognition, word and number recognition

20
Q

Brodmann Area 22, 39, 40

A

Wernicke’s area (language comprehension) - the gyri that comprise this area may be larger or smaller in different people and it is responsible for speech fluency. More precisely, this area allows you to string words together in complete and sensical sentences.

21
Q

Brodmann Area 44, 45

A

Broca’s area (motor speech programming), (cause Broca’s aphasia: a deficit in the ability to speak and produce the proper words/sounds, even though the afflicted person maintains the ability to comprehend language and to mentally formulate proper sentences)

22
Q

Coronary blood vessels

A

the circulation of blood in the blood vessels that supply the heart muscle. Coronary arteries supply oxygenated blood to the heart muscle, and cardiac veins drain away the blood once it has been deoxygenated.

23
Q

Cerebral arteries

A

describe three main pairs of arteries and their branches, which perfuse the cerebrum of the brain. Anterior cerebral artery (ACA) Middle cerebral artery (MCA) Posterior cerebral artery (PCA)

24
Q

Cholesterol

A

a waxy substance found in your blood. Your body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease. With high cholesterol, you can develop fatty deposits in your blood vessels

25
Q

Hypercholesterolemia

A

also called high cholesterol, is the presence of high levels of cholesterol in the blood

26
Q

Cardiac ischemia

A

lack of blood flow and oxygen to the heart muscle. Cardiac ischemia happens when an artery becomes narrowed or blocked for a short time, preventing oxygen-rich blood from reaching the heart

27
Q

Collateral vessels

A

Collateral blood vessels are small capillary-like branches of an artery that form over time in response to narrowed coronary arteries. The collaterals “bypass” the area of narrowing and help to restore blood flow.

28
Q

Angina pectoris

A

chest pain or discomfort due to coronary heart disease. It occurs when the heart muscle doesn’t get as much blood as it needs. This usually happens because one or more of the heart’s arteries is narrowed or blocked (ischemia)

29
Q

Atherosclerosis

A

disease in which plaque builds up inside your arteries.

30
Q

Plaque

A

made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries.

31
Q

Symptoms of high blood pressure

A

Blurred vision Nosebleeds Shortness of breath Chest pain Dizziness Headaches

32
Q

Medicines used to treat high blood pressure

A

Most people need to take more than one type of medicine to lower their blood pressure. ACE inhibitors Angiotensin receptor blockers (ARBs) Calcium-channel blockers Diuretics Alpha-blockers (Doxazocin) Beta-blockers

33
Q

ACE inhibitors

A

work by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.

34
Q

Angiotensin receptor blockers (ARBs)

A

reduce the action of the hormone angiotensin II. This hormone has a powerful constricting effect on blood vessels, increasing blood pressure. Angiotensin II also stimulates salt and water retention in the body, which further increases blood pressure.

35
Q

Calcium-channel blockers

A

disrupt the movement of calcium through calcium channels, reduce the amount of calcium entering cells of the heart and blood vessel walls

36
Q

Diuretics

A

called water pills, are medications designed to increase the amount of water and salt expelled from the body as urine

37
Q

Alpha-blockers (Doxazocin)

A

lowers blood pressure by relaxing your blood vessels so blood can pass through more easily. It’s used to treat high blood pressure and symptoms of an enlarged prostate (benign prostatic enlargement).

38
Q

Beta-blockers

A

block the release of the stress hormones adrenaline and noradrenaline in certain parts of the body. This results in a slowing of the heart rate and reduces the force at which blood is pumped around your body.

39
Q

Hypertension risks:

A

Obesity

Too much salt intake

Not enough fruit and vegetables

Not exercising

African or Caribbean descent

Drinking lot of alcohol

Old age

Family history of high blood pressure

40
Q

Cardiac output (CO) =

A

Stroke volume (SV) x Heart rate (HR)

41
Q

Blood Pressure =

A

Cardiac Output (CO) x Systemic vascular resistance (SVR)

42
Q

Four key diseases associated with hypertension

A

coronary heart disease,

stroke,

vascular dementia and

chronic kidney disease