A&P 3 Exam 1 Flashcards
What is the function of the immune clotting system?
Protection
4 Heart Chambers
R & L Atrium
R & L Ventricles
Adults have how much blood on average?
4-6 Liters
Where is the pulmonary circuit located?
Right side of the heart
What are anti-coagulants?
Medication used to prevent blood clots from forming or growing
Erythrocytes (RBC) principal functions
Carry oxygen from lungs to tissues
Carry CO2 from tissues to lungs
What does the the immune clotting system provide?
Protection
Adults have how much blood?
4 o 6 L
What side is the pulmonary circuit located on?
Right side of heart
What are the four chambers of the heart?
L & R Atrium
L & R Ventricle
What are anti-coagulants?
Medication that prevents the forming and expansion of blood clots
Erythrocytes principal function (RBCs)
Carry oxygen from lungs to tissues
Carry CO2 from tissues to the lungs
Blood is what than water?
Heavier?
Blood is what when oxygen is absent?
Dark Red
What is transportation?
O2, CO2, nutrients, waste, hormones, and stem cells are transported from bone marrow
Blood Types
Antigen (Ag)
Antibody (Anti)
Heart rhythm and contractions are controlled by the cardiac cells in what?
Medulla Oblongata
What is the cardio inhibitory center?
parasympathetic stimulation via the vagus nerve
What is polycythemia
An excess of RBCs
What is anemia?
Deficiency of RBCs or hemoglobin
How many phases of cardiac action potential are there?
4 Phases
What is erythropoiesis
RBC production from hematopoietic stem cells in bone marrow
What are antigens?
Molecules that form on the surface of all cells
Enable the body to distinguish its own cells
What do ventricles do?
Pump blood out of the heart to the lungs and the rest of the body via arteries
Leukocytes/Granulocytes
Neutrophils
Eosinophils
Basophils
What is systole?
Contraction of the heart chambers
What is blood Ph range?
7.35-7.45
Why is Type O the universal donor
The lack of antigens on the RBCs surface= no antigens for the antibodies from the donor blood to attack
What does the atria do?
Receives blood from the heart to pump to the ventricles
What is hematopoiesis
Production of blood
What is Regulation?
Fluid balance, pH, and temp control
What is hemostasis?
The cessation of bleeding
Blood is slightly what than the bodies core temperature?
Warmer
Circulatory System
Heart, blood vessels, and blood
Each hemoglobin protein consists of?
Four protein subunits (globins)
Four heme groups
What are the universal blood types?
Type O and AB+
What is cardiac output?
Volume ejected in each ventricle measured in liters per minute
Functions of the circulatory system?
Transportation, regulation, and protection
Solid (formed elements) are made up of what?
WBCs, RBCs, and platelets
Heart wall is made up of?
Epicardium
Myocardium
Endocardium
What are two erythrocytes disorders?
Polycythemia and anemia
Leukocytes; Agranulocytes
Lymphocytes and monocytes
What are the phases for stimulation of the myocardium
Depolarization
Plateau
Repolarization
Steps of hemostasis
Vascular spasm
Platelet plug formation
Coagulation
What are semi lunar valves?
Control flow from ventricles into great arteries
What is the cardio acceleratory center?
Sympathetic innervation via the cardiac nerves
What is hematopoietic tissue?
All other formed elements produced in bone marrow
Two Primary Heart Sounds
First sound (louder)
Second sound (softer, sharper)
What are the two pathways to coagulation?
Intrinsic and extrinsic mechanisms
What is fibrolysis?
Dissolution of a clot
What is diastole?
Relaxation of heart chambers
Why is AB+ universal blood type?
No anti-A or B antibiotics in plasma
Liquid plasma is made up of what?
Water, proteins, nutrients, electrolytes, and waste
Blood is composed of what?
Plasma and formed elements
What color is blood when bound to RBCs?
Bright red
What is the pericardium?
Double walled sca that encloses the heart
What are AV valves?
control blood flow between atria and ventricles
What are the names of the valves?
Seimlunar and atrioventricular
What are platelets? (thrombocyte)
Small fragments of megakaryocyte cells
Centrifugation order of blood
1st plasma top (yellow)
2nd Buffy coat: narrow bond of WBCs and platelets
3rd RBC: heaviest, settles at the bottom
*Hematocrit; packed cell value
what does the pulmonary circuit do?
transports deoxygenated blood from the heart to the lungs
what does the systemic circuit do?
delivers oxygen, nutrients, and hormones to the body’s organs, tissues, and cells
Hemagglutination essay
-Clmpinfg of red blood cells is a positive feedback loop
-Blood to be tested is added specifically to a serum containing anti A & Anti-B
what is extrinsic mechanism?
initiated by clotting factors that are released by the damaged blood vessel or tissue
What are the hematopoietic stem cells?
-multiple stem cells in bone marrow
-gives rise to all formed elements
must continue creating new cells throughout the lifetime
name the four heme gr
Heme is a respiratory pigment that turns red when it binds to O2
Iron atom (Fe) at core binds O2
Four O2 binding sites per Hb
What are neutrophils
Most abundant 60-70%
Aggressively phagocytes bacteria
What are eosinophils
2-4% total of WBCs
red-orange granules in cytoplasm
What are basophils
Least abundant <1%
many dark violet granules in cytoplasm
What are lymphocytes?
25-33% of total WBCs
large dark nucleus w/ a little cytoplasm
what are monocytes?
3-8% of total WBCs
horseshoe-shaped nucleus (largest WBC)
phagocytizes microbes and cellular debris
What is the OT Interval
time it takes ventricles to contract and relax
what are P waves?
Arial depolarization
what are T Waves
ventricular repolarization
what is the PR Interval
time it takes to travel from atria to ventricles
What is the QRS complex
ventricular depolarization when signals from AV node spread through ventricles
ABO Blood Groups
A Antigen
B Antigen
Both A&B
Neither
Cardiac Conduction System
SA Node
signals spreads throughout atria
atrioventricular bundle
What do leukocytes do?
Travel in blood to combat pathogens and foreign substances
Have a major roles in responding to tissue damage
What is the intrinsic mechanism?
reaction pathway that uses clotting factors that are within the blood itself
Erythrocytes (RBC) are designed to maximize gas exchange and transport
Loses nearly all organelles during development
No mitochondria
No nucleus
Consists mostly of hemoglobins that carry gases
Where is the systemic circuit?
The right side of the heart
Different layers of the pericardium?
Parietal layer
Visceral layer
Pericardial layer
Phases of the cardiac cycle?
Ventricular filling
Isometric contraction
Ventricular ejection
Isovolumetric relaxation
What is the cardiac cycle?
Series of events that occur in the heart during one complete heartbeat
What is antibody?
Proteins secreted as part of a specific immune response when foreign antigens are detected
Bind to antigens and mark them for destruction