A. Fib Medications

Question 1

Vaughan William Class Drugs:
Class I: IA

Drugs (3)
MOA
Affect on AP Duration

Answer 1

Drugs

1. Quinidine
2. Procainamide
3. Disopyramide

MOA: Na-channel blockade

Affect on AP Duration: decrease

Question 2

Vaughan William Class Drugs:
Class I: IB

Drugs (2)
MOA
Affect on AP Duration

Answer 2

Drugs: 
1. Lidocaine
2. Mexiletine
MOA: Na channel blockage
Affect on AP Duration: decrease

Question 3

Vaughan William Class Drugs:
Class I: IC

Drugs (2)
MOA
Affect on AP Duration

Answer 3

Drugs
1. Flecainide
2. Propafenone 
MOA: no change or increase 
Affect on AP Duration

Question 4

Vaughan William Class Drugs:
Class II

Drugs (4)
MOA
Affect on AP Duration

Answer 4

Drugs
1. Metoprolol
2. Atenolol
3. Propanolol
4. Esmolol 
MOA: B-adrenergic blockade
Affect on AP Duration: increase

Question 5

Vaughan William Class Drugs:
Class III

Drugs (5)
MOA
Affect on AP Duration

Answer 5

Drugs

1. amiodarone
2. dronedarone
3. ibutilide
4. dofetilide
5. sotalol

MOA: K-channel blockade
Affect on AP Duration: increase

Question 6

Vaughan William Class Drugs:
Class IV

Drugs
MOA
Affect on AP Duration