A-fib Flashcards

1
Q

CHADSVASc Score, all are 1 point except_______, and thresholds for anticoagulation

A

CHF, HTN, Age >75, DM, Stroke/TIA PMH, Vascular disease, Age 65-74, Sex (female)
Age >75 and Stroke/TIA PMH are the only +2 points
>/=2 males –> chronic anticoagulation
>/= 3 females –> chronic anticoagulation

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2
Q

HASBLED and what it is used for

A

HTN (SBP >160), Abnormal labs (HD, CrCl >2.26 –> +1 point or bili >2x ULN w/ LFTs >3xULN –> +1 point), stroke hx, bleed hx, labile INR, Elderly (>65), Drugs (Et-ol, plavix, NSAIDs –> + 1 point each)
The higher the score, the higher risk of bleed if initiated on anticoagulation

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3
Q

Causes/precipitating factors of afib

A

OSA, HTN, alcohol, hyperthyroid, CHF

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4
Q

goal HR in afib patients

A

</= 110 BPM

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5
Q

non-pharm in afib

A

dec alcohol intake, weight loss, physical activity

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6
Q

rhythm control for afib with non structural heart disease

A

flecainide, propafenone, low dose amio

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7
Q

rate control

A

metoprolol, non-DHPs

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8
Q

rhythm control for afib with structural heart disease/CAD

A

amio, dofetilide, sotalol, dronedarone

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9
Q

rhythm control for afib in patients with HF

A

amio, dofetilide (amio is first choice)

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10
Q

warfarin DDI pneumonic

A

FLAMES
Fluconazole
Levofloxacin (FQs)
Amiodarone
Metronidazole
Erythromycin (macrolides)
Sulfas (Bactrim)

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11
Q

Treatment for torsades

A

4mg IV Mag over 1-2 minutes

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12
Q

Eliquis
when used in afib
dosing in afib
dosing adjustments?

A

5mg PO BID for patients with non-valvular afib

decrease dose to 2.5mg PO BID if at least 2/3 of the following:
1. >/= 80 yo
2. SCR >/= 1.5
3. </= 60 kg

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13
Q

Warfarin
when used in afib
goal INR

A

Used in valvular afib with valve replacements
Target INR 2-3 unless mechanical valve where goal is 2.5-3.5

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14
Q

When to start and stop anticoagulation in accordance to cardioversion

A

start anticoag 3 weeks before cardioversion and continue >/= 4 weeks after achievement of NSR

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15
Q

Class I antiarrhythmics
MOA, drugs (pneumonic), when to not use

A

Na channel blockers
Double Quarter Pounder with Lettuce, Mayo and Fries Please! (Disopyradime, Quinide, Procainamide, Lidocaine, Mexiletine, Flecainide, Propafenone)
NOT for use with structural heart disease or HF!!!

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16
Q

Class II antiarrhythmics

A

beta blockers

17
Q

Class III antiarrhythmics
MOA
Drugs

A

K channel blockers
Dieting During Stress = Ass
Dronaderone, Dofetilide, Sotalol, Amio

18
Q

Class IV antiarrhythmics
Drugs
when to not use

A

Verapamil, Diltiazem
NOT for use in HF

19
Q

Non-DHP CCBs are substrates of _____ and inhbit _______

A

substrates of CYP3A4 and pgp, and inhibit 3A4