A-fib Flashcards
CHADSVASc Score, all are 1 point except_______, and thresholds for anticoagulation
CHF, HTN, Age >75, DM, Stroke/TIA PMH, Vascular disease, Age 65-74, Sex (female)
Age >75 and Stroke/TIA PMH are the only +2 points
>/=2 males –> chronic anticoagulation
>/= 3 females –> chronic anticoagulation
HASBLED and what it is used for
HTN (SBP >160), Abnormal labs (HD, CrCl >2.26 –> +1 point or bili >2x ULN w/ LFTs >3xULN –> +1 point), stroke hx, bleed hx, labile INR, Elderly (>65), Drugs (Et-ol, plavix, NSAIDs –> + 1 point each)
The higher the score, the higher risk of bleed if initiated on anticoagulation
Causes/precipitating factors of afib
OSA, HTN, alcohol, hyperthyroid, CHF
goal HR in afib patients
</= 110 BPM
non-pharm in afib
dec alcohol intake, weight loss, physical activity
rhythm control for afib with non structural heart disease
flecainide, propafenone, low dose amio
rate control
metoprolol, non-DHPs
rhythm control for afib with structural heart disease/CAD
amio, dofetilide, sotalol, dronedarone
rhythm control for afib in patients with HF
amio, dofetilide (amio is first choice)
warfarin DDI pneumonic
FLAMES
Fluconazole
Levofloxacin (FQs)
Amiodarone
Metronidazole
Erythromycin (macrolides)
Sulfas (Bactrim)
Treatment for torsades
4mg IV Mag over 1-2 minutes
Eliquis
when used in afib
dosing in afib
dosing adjustments?
5mg PO BID for patients with non-valvular afib
decrease dose to 2.5mg PO BID if at least 2/3 of the following:
1. >/= 80 yo
2. SCR >/= 1.5
3. </= 60 kg
Warfarin
when used in afib
goal INR
Used in valvular afib with valve replacements
Target INR 2-3 unless mechanical valve where goal is 2.5-3.5
When to start and stop anticoagulation in accordance to cardioversion
start anticoag 3 weeks before cardioversion and continue >/= 4 weeks after achievement of NSR
Class I antiarrhythmics
MOA, drugs (pneumonic), when to not use
Na channel blockers
Double Quarter Pounder with Lettuce, Mayo and Fries Please! (Disopyradime, Quinide, Procainamide, Lidocaine, Mexiletine, Flecainide, Propafenone)
NOT for use with structural heart disease or HF!!!