A&E, Anaesthetics, Ortho and Rheumatology Flashcards

1
Q

Acute Asthma Attack

A

O SHIT ME
Give oxygen 15L high flow through a non-rebreather mask, salbutamol and ipratropium should be given via nebuliser, 100mg IV hydrocortisone also given.
Theophylline (aminophylline) and magnesium sulphate should only be initiated by an anaesthetist - they may suggest NIV or intubation will be more effective.

Remember: moderate 50-70%, severe 33-49% and life threatening is <33% PEFR (with a silent chest, signs of tiring and reduced respiratory effort)

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2
Q

COPD exacerbation

A

iSOAP

  • give ipratropium bromide and salbutamol through a nebuliser
  • give oxygen: if patient is extremely unwell then can give 15L oxygen, however, if patient is conscious and not hypoxic then give 24% oxygen through a Venturi mask. Titrate oxygen concentrations up to 88-92% if a chronic CO2 retainer
  • Antibiotics: only give if there is purulent sputum, yellow/green in colour, otherwise hold back on the antibiotics
  • Prednisolone: give to patients to control exacerbation

Always check the CURB65 score and examination for underlying pneumonia (likely h.influenzae) and treat accordingly.

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3
Q

STEMI

A

ST elevation in territories across:

  • inferior: II, III, aVF (RCA)
  • Anterior: V1-4 (LAD)
  • Lateral: V5-6, I and aVL (left circumflex)

Initial management: MONA+T/C (morphine, oxygen if required, nitrates, aspirin and ticagrelor or clopidogrel - if already on anticoagulation)

If patient presents with chest pain <12hrs and <120 mins to PCI then give PCI
If patient presents with chest pain <12hrs and >120mins to PCI then give thrombolysis - check ECG at 60-90mins and if abnormalities still present then do PCI immediately.

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4
Q

NSTEMI and unstable angina

A

Initial management: MONA+T/C
Doesn’t show ST elevation in leads but may show ST depression and T wave inversion.
Calculate GRACE score, if >3% then consider PCI in 48-72hrs. If <3% then just continue with MONA+T and monitor.
CTCA is really useful for assessing the degree of occlusion and for future surgery planning e.g. PCI or CABG

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5
Q

Ruptured AAA

A

This is a surgical emergency, patients present with abdominal pain and hypotension, may have collapse.
- requires immediate emergency vascular surgery (open) to clamp aorta and resect problem part and insert a graft. This has poor outcomes due to the timescale and severity of presentation.
- initial management is bloods for crossmatch, IV fluids, blood transfusion and compression of the abdomen.
(ABCDE approach)

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6
Q

Haemorrhage

A

dial 2222 and activate the major haemorrhage protocol, take bloods for G&S and crossmatch and request 4 units of blood.
If the patient is on warfarin with major bleeding: IV vitamin K and PCC
If patient is on warfarin with INR >8 and minor bleeding: IV vitamin K
If INR >8 with no bleeding: give oral vitamin K
If INR 5-8 with minor bleeding: give IV vitamin K
If INR 5-8 with no bleeding: withhold 1-2 doses and adjust regular dosing schedule
(Restart warfarin when bleeding has stopped and INR <5)

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7
Q

Overdose :

  • Paracetamol
  • Opiate
  • Benzodiazepine
  • Tricyclics
  • Salicylates
  • Warfarin
  • ## Heparin
A
P = N-acetylcysteine (abdominal pain, liver pathology is a late sign)
O = naloxone (pinpoint pupils, respiratory depression)
B = usually supportive, only give flumenazil if severe due to increased risk of seizures (dilated pupils, respiratory depression, bradycardia)
T = IV sodium bicarbonate (confusion, convulsions, coma, dilated pupils, tachycardia, hypotension, increased tone)
S = IV sodium bicarbonate (abdominal pain, tinnitus, sweating, hyperventilation, N+V)
W = vitamin K (INR or bleeding)
H = Protamine Sulphate (APTT)
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8
Q

Head injury

A

CT head within 1 hour if: GCS <13 at the time or <14 2hrs later, signs of basal skull fracture (racoon eyes, battle’s sign, CSF leak from nose or ear), seizure, focal neuropathy, vomiting >3 times since

CT head within 8hrs if: LOC or amnesia and any of: >65yrs, on anticoagulation medications, dangerous mechanism of injury or >30mins of retrograde amnesia.

CT cervical spine in 1hr if GCS <13 or has been intubated

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9
Q

DKA

A

Ketones and glucose will be high, can be a first presentation of T1DM, often young.

  • Fluid resuscitation is KEY: aim for 1L in the first hour, followed by 1L every 2hrs (+ K if <4.5 = 40mmol or if 4.5-5.5 = 20mmol)
  • Insulin can be given after the first hour (0.1mg/kg/hr)
  • Give 10% glucose 125ml/hr when capillary glucose <14

Children and adolescents are at increased risk of cerebral oedema from rapid fluid resuscitation and should have 1-1 nursing to detect any decline.

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10
Q

Hypoglycaemia

A

Low glucose either due to insulin overdosing or poor oral intake.

  • if patient can swallow then give glucose tablets
  • if patient cannot reliably swallow but is conscious then give glucogel
  • if patient in unconscious then give IV glucose infusion (150ml of 10% glucose)
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11
Q

Anaphylaxis

A
  1. 5mg of IM Adrenaline STAT + 200mg hydrocortisone IV and 10mg chloramphenamine IV
    - give IM adrenaline every 5mins up to 3x
    - also give 15L O2 and salbutamol if there is wheeze
    - IV fluids 500ml STAT
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12
Q

Cardiac Arrest (VT/VF)

A

2222 and state cardiac arrest.
Spend 10 seconds assessing patient - feel for pulse and assess breathing. If nothing then begin CPR at 30:2.
- Give up to 3 shocks by synchronised cardioversion defibrillator, one every 2 mins
- after give adrenaline (1mg) and 300mg amiodarone IV
- Adrenaline 1mg IV should be repeated every 3-5mins

Remember, don’t give adrenaline via PVC due to risk of limb ischaemia - CALL THE ANAESTHETISTS

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13
Q

Cardiac Arrest (Asystole/PEA)

A

2222 and state cardiac arrest
Spend 10 seconds assessing the patient - checking for pulse and RR. If nothing then begin CPR at 30:2. Attach defibrillator pads and allow for rhythm assessment. If PEA or asystole then is a NON-SHOCKABLE rhythm.
- Give adrenaline and amiodarone (adrenaline every 3-5mins)
- Continue CPR constantly, only stopping when signs of life - allow defibrillator to assess rhythm

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14
Q

SVT

A
  1. trial Valsalva manoeuvres intially - avoid dual carotid massage and avoid in elderly patients with potential carotid artery disease
  2. Adenosine IV - give 6mg initially then 12mg then 12mg (spaced apart)
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15
Q

AF (acute onset)

A

if <48hrs or haemodynamically unstable then consider DC cardioversion
If >48hrs and stable then consider delayed cardioversion and give anticoagulation for at least 3W - with either DOAC or LMWH and warfarin

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16
Q

Atrial flutter

A

If <48hrs or haemodynamically unstable then consider DC cardioversion
If >48hrs then delayed cardioversion with at least 3 weeks of anticoagulation

DO NOT GIVE ADENOSINE - this blocks the AV node and allows conduction at 1:1 causing incredibly fast HR of around 300bpm.

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17
Q

Stroke

A

Calculate ROSIER score and do CT head urgently.

  • if CT head does not show bleed then give Aspirin 300mg
  • Do not attempt to lower BP unless is malignant as this can further reduce perfusion

If ischaemia <4.5hrs = thrombolysis
If ischaemic <4.5hrs and in proximal anterior circulation occlusion with evidence of salvageable brain tissue = thrombolysis and thrombectomy in <6hrs
If >4.5hrs or a ‘wake up’ stroke = thrombectomy in 24hrs

If haemorrhagic = refer to neurosurgery, may require burr hole surgery or craniotomy or conservative management - this is at surgeons discretion and takes into account patient’s pre-morbid state.

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18
Q

Pulmonary embolism

A

ECG: sinus tachycardia is most common but S1Q3T3 is more specific ECG finding
Provoked: apixaban for 3M and treat the underlying cause
Unprovoked: apixaban for 3-6M
Active cancer: warfarin for 6M
APS: if PE then lifelong warfarin
Massive: thrombolysis within 48hrs and continuous heparin infusion.

CTPA is gold-standard: in pregnancy carries a risk of maternal breast cancer, remember it requires contrast so not suitable in severe CKD or contrast allergy.
V/Q scan is alternative: increased risk of childhood cancers in pregnant women.

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19
Q

Simple Pneumothorax

A

Primary: no underlying lung conditions and:

  • <2cm with no SOB = discharge with worsening advice
  • > 2cm or SOB = aspirate and if fail then test drain inserted

Secondary: underlying lung condition (COPD)
- <1 cm = give oxygen and admit for 24hrs
- 1-2cm = aspiration attempted, if fail then chest-drain inserted
- >2cm or SOB = chest drain inserted, no aspiration attempted
(admit all for 24hrs of observations)

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20
Q

Tension pneumothorax

A

Deviation of the trachea away from the affected lung.

  • emergency decompression by large bore cannula inserted into 2nd intercostal space, mid-clavicular line
  • do not wait for investigation result
  • insert chest drain after initial decompression
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21
Q

Hyperglycaemic hyperosmolar state (HHS)

A

GIVE LOTS OF FLUID

  • give around 9L of fluid to these patients
  • if glucose is still remaining high then consider 0.05mg/kg/hr of insulin but only if not lowering with fluids alone.
  • give prophylactic dose of LMWH due to increased risk of VTE
  • stop metformin due to risk of lactic acidosis in patients with dehydration - continue insulin and oral glycaemics however. Also consider stopping ACEi, ARBs, NSAIDs and diuretics.
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22
Q

Seizure

A

Patients have status epilepticus if seizure activity is sustained for >5mins

  • give 4mg IV lorazepam or 10mg IM diazepam (give at 10mins, 20mins)
  • If seizure activity not stopped by 30mins then give phenytoin
  • If seizure activity still ongoing then consider GA and ventilatory support
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23
Q

Carbon monoxide poisoning

A

high flow O2 and supportive treatment
- may require hyperbaric oxygen

Remember it can give a falsely high O2 saturation reading, presents with headache, N+V

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24
Q

Sepsis

A

Do the following within 1hr:

  • Take bloods and blood cultures
  • Take lactate and ABG
  • Take urine output
  • Give IV fluids (500ml saline)
  • Give IV antibiotics (according to local guidelines)
  • Give Oxygen (15L through non-rebreather)
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25
Q

DIC

A

Can be recognised by low platelets, high PT, high APTT, and low fibrinogen

  • treat underlying condition e.g. sepsi
  • get help from seniors/haematology
  • can give platelets (aiming for count >50), clotting factor concentrate and cryoprecipitate if the fibrinogen is dangerously low.
26
Q

Malignant hyperthermia

A

Caused by inhaled anaesthetics or suxamethonium. May have a family history. Causes an increase in metabolism and sustained muscle contraction resulting in increased sweating, temperature, poor respiratory function (increase end-tidal CO2)

  • remove the causative agent and stop surgery, maintain propofol infusion
  • active cooling techniques + dantrolene (blocks sarcoplasmic reticulum)
  • transfer to ICU
27
Q

Spinal overdose (total spinal anaesthesia)

A

Due to overdose of a spinal or accidental intra-thecae injection of epidural. Causes respiratory and cardiac arrest: hypotension, apnoea, LOC and mydriasis

  • requires immediate intubation and CVD support with catecholamines and dolbutamine.
  • avoided by giving a test-dose when carrying out an epidural to ensure correct placement. Numb legs suggests malplacement
28
Q

Epidural complications

A

Pain, dural puncture (headache), spinal-epidural haematoma, epidural abscess and hypotension

29
Q

Post-op analgesia

A

Epidural can be a great method of post-op analgesia for obstetric and abdominal surgery as it can be topped up easily. Spinal is not used for post-op as it wears off relatively quickly.
Patient controlled analgesia allows the patient to administer morphine via IV system in response to pain - need to be aware of toxicity.
- look out for respiratory depression, jerky movements and pin-point pupils and confusion

30
Q

Local anaesthetic systemic toxicity

A

Caused by accidental injection into blood vessels by the clinician - this is why you always aspirate before injecting anaesthetic.
Can cause tinnitus and seizures, bradycardia and arrythmias

31
Q

Rheumatoid arthritis

A

Start on DMARDs within 3M of symptom onset for the best outcomes.

  • give methotrexate + folic acid and always check CXR for ILD
  • also can start NSAIDs, intra-articular steroids for symptomatic relief
  • TNFalpha if unresponsive to 2 DMARDs and DAS28 score showing high disease activity (>5.1 = severe disease)
32
Q

SLE

A

Skin + joint = hydroxychloroquine, topical steroids and NSAIDs

Other organ involvement e.g. lung or renal = azathioprine + steroids

33
Q

Systemic Sclerosis

A
Raynaud's = CCB, iloprost or bosartan 
Renal = ACEi
ILD = cyclophosphamide
Oesophageal = PPI
34
Q

CREST

A

Raynaud’s = CCB, iloprost or bosartan

Oesophageal dysmotility = PPI

35
Q

Gout

A

Acute: give NSAIDs first line (ibuprofen or diclofenac) or if unsuitable then give colchicine
Prophylaxis: diet modifications and allopurinol

  • negatively birefringent needle shaped urate crystals
36
Q

Pseudogout

A

Acute: give NSAIDs first line (ibuprofen or diclofenac) or if unsuitable then give colchicine
Prophylaxis: allopurinol is of no use as there is no rise in rate levels

  • positively birefringement rhomboid shaped pyrophosphate crystals with evidence of chonedrocalcinosis on XR
37
Q

Polymyalgia rheumatica

A

Give 15mg of Prednisolone OD and gradually reduce over 18M

- muscles are stiff and weak but not sore

38
Q

Temporal arteritis

A

Give 40mg of Prednisolone (60mg if visual impairment) stat, arrange temporal artery biopsy and urgent ophthalmology review if there are visual symptoms

39
Q

Polymyositis

A

Give 40mg of Prednisolone + methotrexate or azathioprine

- causes pain, weakness, and raised CK usually >10,000. Anti-Jo1 is often raised

40
Q

Dermatomyositis

A

Give 40mg Prednisolone and initiate methotrexate or azathioprine treatment
- Shawl rash, gottron’s papule and heliotrope rash on forehead and across nose

41
Q

Sjogren’s

A

Lubricating eye drops (pilocarpine), saliva replacements
Hydroxychloroquine
Anti-Ro and Anti-La

42
Q

APS

A

Primary prevention: daily low dose aspirin

Secondary prevention: lifelong warfarin (if pregnant or wanting to get pregnant then LMWH)

43
Q

Ankylosing spondylitis

A

Axial disease: topical NSAIDs, physiotherapy and exercise - relieves the enthesitis

Spinal and peripheral disease: IM or IA steroids, oral steroids and DMARDs

Anti-TNF for severe aggressive disease

44
Q

Psoriatic arthritis

A

DMARD: Methotrexate works very well

45
Q

Fibromyalgia

A

Validate the patients pain
Graded exercise and physiotherapy
Atypical analgesia (neuropathic) e.g. gabapentin, amitriptyline
CBT can be helpful

46
Q

Hip fractures:

  • Intracapsular displaced
  • Inter-trochanteric
  • Sub-trochanteric
A

If patient has good mobility and displaced IC # = THR
If poor mobility and displaced IC # = hemiarthroplasty
EC intertrochanteric # = dynamic hip screw
Sub trochanteric = intramedullary nail

47
Q

Capal tunnel syndrome

A

Splint at night and corticosteroid injections

48
Q

Cubital tunnel syndrome

A

surgical release of Osborne’s fascia

49
Q

Frozen shoulder

A

Aggressive physiotherapy to prevent worsening stiffness, joint injections have some use
- MUA can be useful in releasing the frozen capsule

50
Q

Osteoarthritis

A

Topical NSAIDs, paracetamol, physiotherapy and walking aids or occupational therapy
- to be a candidate for joint replacement the patient must lose weight, actively participating in physiotherapy for >1yrs and be on top paracetamol dosing with uncontrolled pain

51
Q

Bone Values and diseases:

  • osteoporosis
  • osteomalacia
  • Paget’s disease
  • CKD
  • Hyperparathyroidism
A

OP: normal values
OM: low Ca, low Phos, High ALP and High PTH
P: High ALP, low Ca, low Phos, low PTH
CKD: Low Ca, high Phos, high ALP and high PTH
HPTH: High Ca, high PTH, low/normal ALP and Phos

52
Q

Bone tumour features

A

Osteosarcoma: sunburst appearance
Osteoid osteoma: sclerotic halo
Ewing’s sarcoma: onion skin

53
Q

DDH

A

Ortolani and Barlow screening tests in newborn exam, USS hips in high risk (first baby girl, macrosomia, breech)

  • use pavlik harness full time for 6W until the age of 4-6M
  • if undetected, patients will tip-toe walk on one side, have leg length discrepancy due to failed acetabulum development
  • May require hip replacements
54
Q

Transient synovitis

A

manage conservatively with NSAIDs and rest. Patient is systemically well following a viral infection

55
Q

Perthes disease

A

hyperactive boys with hip pain and limp due to AVN of the femoral head. Requires decreased activity to prevent deformity of the femoral head.
- may require surgery if not improving

56
Q

SUFE

A

Obese adolescents with knee pain and limp

  • requires urgent surgical fixation of the femoral head
  • MUA risks AVN and may not be successful.
57
Q

Duchenne’s MD

A

Has not cure, treatment is supportive with physiotherapy, walking aids and eventual respiratory support as the condition progresses
- due to X-linked genetic defect in dystrophin

58
Q

Scaphoid fracture

A

Undisplaced and no XR evidence: repeat imaging at 7-10 days
Undisplaced and visible on XR: splint for 6-12W
Displaced: surgical fixation with a compression screw (due to risk of AVN)

Patients have a FOOSH, pain over the anatomical snuffbox and pain on thumb telescoping

59
Q

Supracondylar fracture

A

Check peripheral pulses (radial artery intact) and medial nerve (make OK sign)

60
Q

Humeral shaft fracture

A

Check radial nerve - forearm extension (wrist drop) and parasthesia of the posterior forearm and dorsal hand.
- kids remodel well and can accept a lot of displacement before surgery considered.