A&E Flashcards
Tests + Mx of persistent haematuria
- Dipstick, 3 sampes 2-3 weeks apart
- Renal function, ACR or PCR ratio and BP
- Microscopy
- Urgent referral if >/45 with UEVH with no UTI/persistent after uti Tx. oR 60+ AND UE non visible H and dysuria or WCC
The triad of nephrotic syndrome and patho
- Nephrotic syndrome = proteinura, hypoalbuminaemia, oedema
- Caused by primary (minimal change disease etc), or secondayr causes (DM)
- Patho = damage to basememnet membrane and increased permeability to proteins
- Ix = Dip, MSU (exclude infection), FBC, Coag, U&Es and quantify protein.
When not to diagnose a UTI with Dipstick and when to send off MSU
- DOnt use dipstick for = women>65, men and catheterised patients
- Send a culture if = women 65+, men, pregnant, recurrent UTI (2 ep in 6m or 3 in 12m), haematuria
Definition of neuropathic pain and first line Tx
- NP pain = damage/disruption to the NS
- mitriptyline, duloxetine, gabapentin, pregablin.
Pllaiative prescribing - pain
- If no co-morbidities = 20-30mg MR with 5mg breakthrough
- 1/6 is breakthrough generally
- Prescribe laxative like senna + macrogol/docusate with it
- If ckd = OXYCODONE AND IF MORE SEVERE THEN FENTANYL ETC.
Acute interstitial Nephritis
- Drug induced AKI
- penicillin, NSAIDs, rifampicin, allopurinol, furosemide, infections, systemic disease
- Interstitial oedema and infiltrate
- fever, rash, eosinophilia, HTN etc
- White cell casts
- Canget tubulointersitital nephritis with uveitis in yougn women
Three main causes of AKI
- Pre-renal = lack of blodo flow (hypovolaemia, renal artery stenosis)
- Intrinsic = intrinsic damage - glomerulonephritis, tumour lysis syndrome etc
- POst-renal = obstructive - ie kidney stone, BPH, external compression of ureter
Drugs that commonly cause / can increase irs of AKI
- NSAIDs
- Aminoglycosides
- ACEi
- ARB
- Diurrtic
Diagnosis of AKI
- Rise in creatinine of 26 umol/L or more in 48 hours OR
- > / 50% rise in creatinine over 7 days OR
- Fall in urine output less than 0.5ml/kg/hour for more than 6 hours in adults (8hr in children)
- > /25% dall in eGFR in children/young adults in 7 days
Anaphylaxis symptoms and doses of adrenaline
- Sudden + rapid = airway +/- breathing +/- ciruclation problems (stridor, angioedema, hoarse voice, wheee, SOB, hypotension, tachy)
- Under 6months = 100-150 micrograms (0.1-0.15ml 1 in 1000)
- 6 months to 6 years = 150 micrograms (0.15ml 1 in 1000)
- 6-12 years = 300 micorgrams (0.3ml 1:1000(
- Adult and child over 12 = 500 micrograms (0.5ml 1:1000)
Can repeat every 5 mins, anterolateral aspect thigh. If use 2 and still anapphylaxis then refractory and expert help for ocnsideration iV adrenaline infusion.
How to manage patients after stabilisation of anaphylaxis
- Non-sedating oral antihsitamines
- Serum tryptase can remain elevated up to 12hours after anaphylaxis for confirmation
- If new diagnosis then specialist allergy clinic and given epipen in mean time (2) and trained.
Placental abruption vs placenta praevia (Antepartum haemorrhages)
- Placental abruption = shock out of keeping with visible loss, constant pain, tender/tense uterus, normal lie/presentation, absent/distressed fetal heart, coag problems etc
- Placenta praevia = shock in proportion to visible loss, no pain, uterus not tender, lie and presentation may be abn, fetal heart usually nromal
Types of miscarriage
- Threatened = painless vaginal bleeding <24weeks, cervical os closed
- Missed 9delayed) = dead fetus <20 weeks with no signs expulsion. May have some bleeding. Os is closed.
- Inevitable = hevay bleeding, os opened
- Incomplete = not all products expelled, pain, vaginal bleeding, os opened
Mx animal / human bites
- Animal = clean, close, co-amox
- Human bites = co-amox, consider HIV/Hep C
Lyme disease symptoms and management
- bulls eye rash, systemic feautres (headache, lethargy, fever, arthralgia) and later on CV problems and neuro
- Dx = clinical and ELISA antibodies first line
- Asymptomatic = remove
- Suspected/confirmed lymes = doxycycline if early. Ceftriaxone if disseminated.
Mx heat, electrical and chemical burns
- A,B,C
- Heat = remove from source, 10-30mins water (not iced). Cover and layer cling film around
- Electrical = switch off power, remove from source
- CHemical = brush of powder then irrigate with water
Shockable vs non shockable rhythms
- SHockable = VF or pulseless VT
- Non shockable = asystole, PEA
adrenaline/amidoarone rules with ALS
- Adrenaline = 1mg ASAP if non shockable and repeat every 3-5mins. If shockable then start adrelaine 1mg after 3rd shock.
- Amidoarone = 300mg in VF/Pulseless VT after 3 shocks,. Further 150mg after 5 shocks.
- If suspected PE then thrombolytic drugs but continue CPR 60-90mins.
Reversibel causes Cardiac arrest
- Hs = Hypoxia, hypovolaemia, hyperkalaemia, hypokalaemia, hypoglycaemia, hypocalcaemia, (othe rmetbaolic), Hypoerthermia
- Ts = Thrombosis, tension PTX, tamponade, toxins
Paeds Bls
- 5 Rescue breaths -c heck brachial or femoral pulse
- 15:2
- COmpressions in lower half of sternum. In infants use two thumb encircling technique
ACS features
- Chest pain - LHS, may radiate to left arm or neck. If elderly/diabetc/female can be more atypical
- SOB
- N&V
- Sweating
- Palpitations
Features aortic dissection
- Chest/back pain - sharp, severe, tearing, maximal at onset
- Pulse deficity between arms (>20)
- Aortic regur, HTN, anginal, paraplegia, limb ischaemia etc
Key/common causes chest paina nd features
Immedate mx of suspected acs
- Morphine if severe pain
- Oxygen if <94
- Nitrates - GTN
- Aspirin 300mg
- ECG - but dont delay transfer.
emegrency amdission if in under 12 hours. if 12-72hrs ago the same day assessment and if >72houts then do ECG/trop before deciding.
If its stable angina then CT coronary angiography
ECG territories of STEMI changes.
Myocarditis presentation, Mx
- Young patient, acute hx, chets pain, sob,a rrhythmias.
- Bloods (inflamm markers, cardiac enzymes, bNP all elevated).
- ECG - tachy, arrhythmias - st/t wave changes include st elevation and t wave inversion
- Tx of undelrying cause ie, Abx if bacterials.
Acyanotic vs cyanotic heart disease
- Acyanotic = VSD, ASD, PDA, Coarctationa orta, aortic valve stenosis
- Cyanotic = tet of fallor, transposiiton greta arteries, tricuspid atresia.
- In cyanotic - PG E1 (eg, alprostadil) to maintain PDA
Extradural haematoma - key Hx, how it is on CT
- Middle meningeal artery (pterion hit)
- Lucid interval after head injury
- Biconvex (lentiform) hyperdense collection, limited by suture lines of skull
GCS
Features and tx of hypoglycaemia
- Sweat, hake, hunger, anxiety and if severe - visual, confusion, coma, weakness
- 102-g oral glucose or snack
- If hospital and unconscious then iV glucose 20% 100ml and if no cannula or community = IM glucagon
Features / Ix SAH
- Sudden onset headache, severe, occipital, peaks 1-5mins, N/V, meningism, seizures
- CT non contrast
- If a CT is done over 6 hours after symptom onset and normal then do LP (xanthochromia etc). Dont do LP if CT wihtin 6 hrs.
- Neurosrgery
- CX = re bleeding, hydrocephalus, vasospasm, hyponatraemia, seizures
SUbdural: Types, Presentation, CT
- Colleciton blood deep to dural laye
- Acute = symptoms within 48hours injury and rapid neuro deterioration. CT is cresenteric not limtied by sutures.
- Subacute = symptoms manifest within days-weeks ost-injury with more gradual progression.
- Chronic = common in elderly and alocholics, developing over weeks to months. May not recall specific head injury. CT is cresenteric, not restricted by sutures, compress brain (mass effect). In contrast to acute ones, these are hypodense (dark) vs acute which is bright. COuld be conservative mx.
Ams, fluctations in consciousness, focal neuro deficits, headache one side and worsening, seizures
Papilloedema, pupil changes, gait abnormalities, hemiparesis
Mmeory loss, perosnality changes
N&V, drowsy, raised intracranial pressure signs