A bit of everything Flashcards

1
Q

What 4 questions can be asked to assess mental capacity?

A

Does the patient Understand the information relevant to the decision?
Can the patient Retain the information?
Can they use the information to Weigh up the options and make a decision?
Can they Communicate their decision to you?

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2
Q

What is DOLS?

A

Deprivation of Liberty Safeguards
DOLS are part of the MCA, the safeguards aim to ensure that people in care homes or hospitals who lack capacity are looked after in a way that has their best interests at heart

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3
Q

What is an IMCA?

A

Independent Mental Capacity Advocate = a legal safeguard for people who lack capacity
They represent people when there is no one independent of service –> e.g. no family members/friends

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4
Q

What is the ICD-10 criteria for depression?

A

Persistent low mood
Loss of interest
Fatigue or low energy

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5
Q

Give 5 physical symptoms of depression

A

Sleep disturbance
Unexplained aches/pains
Appetite change
Loss of libido

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6
Q

Give 5 psychological symptoms of depression

A

Continuous low mood
Feeling hopeless
Tearful
Guilty

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7
Q

What investigations might you do in someone with depression and why?

A

Bloods –> glucose, U&Es, LFT, TFT, Ca, FBC, ESR/CRP
Imaging if there are features suspicious of an intracranial lesion
Done to exclude any organic cause

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8
Q

Name a screening tool for depression that can be used in primary care

A

PHQ-9

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9
Q

How would you among mild-moderate depression?

A

Active monitoring
Low intensity psychological intervention –> IAPT, CBT
Encourage lifestyle changes such as exercise, smoking cessation and healthy diet

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10
Q

How would you manage moderate-severe depression?

A

High intensity psychological intervention
2. Anti-depressant –> SSRIs, SSNRI, NASSAs, TCA, MAOIs

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11
Q

Name 3 Selective Serotonin Reuptake Inhibitors (SSRIs)

A

Fluoxetine
Citalopram
Sertraline

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12
Q

Name a Selective Serotonin-Norepinephrine Reuptake Inhibitor (SSNRI)

A

Duloxetine

Venlafaxine

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13
Q

Name a Noradrenaline and specific serotogenic antidepressants (NASSAs)

A

Mirtazapine

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14
Q

Briefly describe section 2 of the mental health act

A

Admission for assessment –> allows compulsory admission for up to 28 days for assessment

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15
Q

Briefly describe section 3 of the mental health act

A

Admission for treatment –> allows compulsory admission for up to 6
months for treatment

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16
Q
A
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17
Q

Briefly describe section 135 of the mental health act

A

A magistrate can authorise forced entry into a property where it is believed that a person is suffering from a mental health disorder

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18
Q

Briefly describe section 136 of the mental health act

A

Used by police to take someone suffering from a mental health disorder form a public place to a place of safety

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19
Q

Give 4 physical signs of anxiety

A

Restless
Difficulty falling asleep due to racing thoughts
Dizziness
GI Disturbance –> Nausea, diarrhoea, constipation
Increased HR, BP and sweating
Muscle tension
Shortness of breath

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20
Q

Give 3 psychological symptoms of anxiety

A

Excessive worry
Uncontrollable racing thoughts
Difficulty concentration due to agitation or racing thoughts
Sense of dread and fearing the worst
Feeling tense and nervous and unable to relax
Rumination = thinking about bad experiences over and over again

148
Q
Name 3 possible causes of anxiety

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21
Q

Name 3 possible causes of anxiety

A

Family history
Female
Traumatic events
Other mental health problems
Chronic illness
Medications –> antidepressants, corticosteroids, OCP
Menopause

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22
Q

What is generalised anxiety?

A

Regular or uncontrollable worries about many different things in everyday life
- Subjective experience of nervousness

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23
Q

What is social anxiety?

A

Experience of extreme fear or anxiety triggered by social situation (parties, workplaces, or everyday situations where you have to speak to a different person)

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24
Q

What is a panic disorder?

A

Having regular or frequent panic attacks without clear cause or trigger

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25
What are the characteristic features of panic disorders?
crescendo of the anxiety usually resulting in an exit from the direction Somatic symptoms –> palpitations, sweating, trembling,SOB, chest pain, dizziness Secondary fear of dying/losing control
26
What is a phobia?
Extreme fear or anxiety triggered by a particular situation - HAve anticipatory features
27
Give 2 examples of phobia
Agoraphobia = crowds, public places, leaving home Claustrophobia = small, enclosed spaces Arachnophobia = spiders Social phobia
28
What are the characteristic features of PTSD?
Hyperarousal –> persistently heightened perception of current threat Avoidance of situation/activities Emotional numbing Re-experiencing –> flashbacks, nightmares
29
Describe the treatment of anxiety
Psychoeduction, sleep hygiene, self guided CBT, relaxation techniques CBT Pharmacological treatments
30
What is included in a MSE?
Appearance and behaviour Speech Mood and Affect Thought Perception Cognition Insight
31
What formula is used to work out how many units of alcohol are in a drink?
Strength of drink (%ABV) X Volume (ml) / 1000
32
Name 4 possible alcohol withdrawal medications and how they work
Acamprosate –> relieves cravings- NMDA receptors antagonist Disulfiram –> make you suffer when drinking - inhibits aldehyde dehydrogenase Naltrexone –> block opioid receptors in the brain
33
Pathophysiology of DKA
1. Blood glucose raised due to peripheral insulin deficiency 2.Causes a rise in glucagon further raising the blood glucose 3.Leads to an accelerated breakdown of adipose tissue into free fatty acids which oxidise into ketones. 4.Hyperglycaemia and glycosuria lead to osmotic diuresis = dehydration
34
Features of DKA
>3mmol/L blood glucose 11mmol/L
35
What is raised in CAH?
17 hydroxyprogesterone
36
What are the features of CAH?
Increased androgens so virillisation of genitalia - clit hypertrophy Precocious puberty Early development of pubic hair Salt wasting crisis Hypokalaemia Hypernatraemia Metabolic acidosis
37
What is androgen insensitivity syndrome and the sx ?
46 XY - Primary amenorrhoea Undescended testes Little or no pubic hair
38
where is wernicke aphasia? What would it sound like?
superior temporal gyrus Fluent but no comprehension
39
What is Broca's aphasia?
Inferior frontal gyrus Not fluent but comprehensive
40
What is BV and what is seen microscopically?
Overgrowth of gardnerella vaginalis Produces aerobic lactobacilli Clue cells
41
What and when are the tests for Downs?
Combined test at 11-14 (raised nuchal translucency, raised B-HCG, low PAPP-A) Quadruple test 15-20 weeks ( Low Alpha feto protein, low unconjugated oestriol,, raised HCG and raised inhibin A) Chorionic villious sampling - 10-12 week Amniocentesis - 15 -20 week
42
Explain the menstrual cycle?
Follicular - FSH slowly rises and causes follicles to mature. Maturing follicles produce oestrogen (oestrogen inhibits FSH) as the follicles mature, more oestrogen is produced until there is a peak which causes LH surge which causes ovulation. LH maintains corpus luteum. Corpus luteum produces progesterone and oestrogen which maintains and causes proliferation of the lining. Corpus luteum breaks down causing menstruation.
43
When should a breast referral be made?
Over 30 with an unexplained breast lump with or without pain Over 50 with unexplained nipple changes Over 30 with an unexplained lump in axilla
44
what are the first rank symptoms of schizophrenia?
third person auditory hallucination Passivity phenomena Delusion of perception Thought disorders
45
What is sensitivity?
Proportion of the people who have the disease that were correctly identified.
46
What are the features of opioid misuse?
constricted pupils drowsiness rhinorrhea Tremor
47
What is specificity?
Proportion of people who dont have the disease that were correctly excluded from the test
48
What is the cause of premature neonate RDS?
Deficient surfactant from T2 pneumocytes due to prematurity causing alveolar collapse. The baby will have fluid in their lungs during birth, when they take their first breath, the surfactant sould decrease the surface tension so the alveoli dont collapse. No surfactant = collapse
49
what is egalitarian?
Everyone is provided with all the necessary care
50
What is maximising?
An act is evaluated solely on its consequences
51
what is cyanosis?
more than 5g/dl of deoxygenated blood
52
what are the red flags for a CT <1 hour?
Vomiting more than once, GCS 13 on initial assessment, focal neuro, post traumatic seizure
53
What is syphillis?
treponema paliidum - sprochete bacterium
54
What are the features of primary syphillis?
chancre, local non tender lymphadenopathy
55
features of secondary syphillis?
generalised maculopapular rash, codylomata lata, alopecia
56
Features of tertiary syphillis?
neurosyphilis, cardiogenic
57
Investigations for syphillis?
VDRL, PCR/TPPA
58
TX for syphillis?
Benzathine penicillin G
59
What is the complication after ABX for syphillis?
Jarisch herxheimer reaction
60
what is the Mcroberts manouver?
hips and knees are flexed and abducted. provides a posterior tilt lifting pubic symphysis up
61
Rf for shoulder dystocia?
high maternal BMI Prolonged labour Gestational diabetes
62
Risk factors for GORD?
Hiatus hernia Obesity FHx of GORD Downs
63
What are the symptoms of Brown sequard cord compression?
Hemisection Ipsilateral corticospinal +DCML Contralateral - spinothalmic
64
Treatment for cord compression?
Dexamethasone and surgical decompression
65
Symptoms of optic neuritis?
Decreased unilateral visual acuity Poor discrimation of colour Eye pain on movement scrotoma
66
What is seen on CSf for bacteria?
cloudy, low glucose, high protein, polymorph WC
67
What is seen on CSF for virus?
clear, normal protein, lymphocytes
68
what is cerebral palsy?
a chronic disorder of movement and posture due to a non progressive brain abnormalities occurring before the brain has fully developed.
69
Toxicoplasmosis infection features? and TX
IUGFR, enceph Pyremethamine and sulfadazine
70
Rubella infection features? Foetus and TX
Blueberry muffin rash, SNL, congenital cataracts
71
HSV foetal infection features? and Tx
encephalopathy IV aciclovir
72
CMV infection features and TX?
BM rash, vague Tx IV ganyclovir
73
Shyphillis infection foetus features?
Kerasitis, frontal bossing, SN deafness TX IV benzathine penicillin
74
RF for ectopic preg?
IUD PID Endometriosis Previous ectopic IVF Pelvic surgery
75
RF for cord prolapse?
Polyhdraminos Prematurity Artifical rupture of membranes
76
RF for vasa praevia ?
Placenta praevia Multiple pregnancy Low birth weight
77
Rf for placenta praevia
Previosu placenta praevia Previous Csection Multople pregnancies >35 Uterine surgery
78
Rf for placenta increta?
Previosu csection Uterine surgery Hx of placenta praevia >35
79
RF for endometrial ca?
nullparity early menarche late menopause obesity PCOs Diabetes
80
Vulval Ca RF
HPV Lichen sclerosis VIN Immunosuppresison
81
Cervical cancer RF
HPV Multiple sexual partners smoking High parity HIV
82
Ovarian Ca Rf
BRCA 1 Early menarche LAte menopause Nulliparity
83
What are the symptoms of endometriosis?
Dysparaenia Dysmenorrhoea Dysuria Pelvic pain
84
What is seen on a pelvic examination with someone who has endometriosis?
fixed retroverted uterus Tender uterus Nodules
85
What is biochemically seen in PCOS?
LH:FSH ratio - LH raised Low sex hormone binding globulin possibly raised prolactin and testosterone
86
What is biochemically seen in menopause and premature ovarian failure?
Raised FSH and LH
87
what is the most common type of endometrial cancer?
Adenocarcinoma
88
Advantage of transtheoretical model?
acknowledges individual steps of readiness Gives an idea of time frame
89
Disadvantage of transtheoretical model?
not all people move through each stage No social cues People go forward and back
90
what are the features of tuberous sclerosis?
ash leaf spots Infantile spasms developmental delay Retinal harmatomas Autosomal dominant
91
What are the features of neurofibromatosis 1 ?
Cafe-au-lait spots Axillary/groin freckles Peripheral neurofibromas Iris hamatomas Scoliosis Pheochromocytomas
92
What bacteria causes whooping cough?
Bordella pertussis - gram negtive coccobacillus
93
What immunisation is recommended for children with T1DM?
influenza
94
How do you calculate the APGAR score?
Colour - pink = 2, blue extremities =1, cyanosis = 0 Muscle tone - active movement =2, limb flection =1, flaccid Reflex irritability - cries on stimulation = 2, grimace = 1 Pulse rate - >100=2 ,<100 = 1 Respiraotry effort - strong cry =2, weak = 1
95
what is the treatment for bacterial meningitis?
<3months= cefotaxime and amoxicillin >3months - ceftriaxone
96
What is the kernig's sign ?
Knees are flexed, a clinician extends the knee which cause resistance, pain or the knees wont flex
97
What is parkinson's disease?
neurodegenrative disorder caused by degeneration of dopaminergic neurons within the substantia nigra.
98
What are the main features of parkinsons?
Bradykinesia Rigidity Tremor
99
What are other features of parkisnons?
mask like faces drooling Postural hypotension
100
What are causes of parkinsonism?
Parkinsons disease Drug induced Multiple system atrophy - Autonomic disturbance Progressive supranuclear palsy - impairment of vertical gaze
101
What scoring system is used for prostate cancer?
Gleason
101
What are the causes of raised PSA?
BPH, prostate cancer, prostatitis
102
What LFT would be seen in prostate cancer?
Alkaline phosphate
103
What drug is given with levodopa and why?
Decarboxylase inhibitor and to reduce the peripheral breakdown of levodopa to reduce side effects
104
What are the features of brown sequard?
ipsilateral loss of fine touch, proprioception, vibration and ipsilateral hemiplegia - contralateral loss of pain and temp sensation. Weakness below lesion
105
What causes otitis media?
Streptococcus pneumonia Adenovirus rhinovirus
106
what are the symptoms of pre-eclampsia?
Headache papilledema RUQ pain hyperreflexia Proteinuria
107
What are the high risk factors for pre-eclampsia?
DM CKD SLE/ALP
108
What are the moderate risk factors of pre-eclampsia?
first pregnancy age 40 years or older pregnancy interval of more than 10 years body mass index (BMI) of 35 kg/m² or more at first visit family history of pre-eclampsia
109
When should you take aspirin in pregnancy?
Take it from 12 weeks until birth - 1 high risk or 2 low
110
what are the common effects of levodopa?
dry mouth psychosis postural hypotension
111
What is regularly taken with levodopa and why?
decarboxylase inhibitor - decreased peripheral breakdown of levodopa to reduce side effects
112
what are examples of Parkinson's medication?
Dopamine receptor antagonist - Bromocriptine Monoamine oxidase B inhibitors - selegilline COMT (Catechol-O-Methyl Transferase) inhibitors - entacapone
113
What adverse effects are there when achieving a specific dose for Parkinson's medication?
on-off phenomenon - fluctuations in motor period. end of dose wearing off
114
what advice would you give parents when there child has just been diagnosed with epilepsy?
Take caution with swimming If a seizure happens >5 minutes ring 999
115
what tests are done to assess fall risk?
Turn 180 test Timed up and go
116
What is seen due to rhabdomyolosis?
myoglobinuria
117
What are the Sx of infective exacerbation of COPD?
Fever Productive cough Wheeze Fatigue Cyanosis Confusion
118
what is the cause of excerbation of COPD?
Haemophilus influenza Streptococcus pneumoniae
119
What are the signs of life threatening attack?
Silent chest Sats <92% Cyanosis Poor respiratory effort Altered consciousness PEF <33% best or predicted
120
What is the treatment regime for acute asthma?
nebulised salbutamol nebulised ipatropium bromide oral prednisolone or IV hydrocortisone if they cant tolerate it IV magnesium sulphate IV aminophylline IV salbutamol Senior review
121
what are the side effects of atypical antipsychotics?
Weight gain Metabolic disturbance - impaired glucose tolerance
122
what are the side effects of emergency contraception?
Heavy/ painful periods Infection Coil coming out
123
What are the assessments used for depression ?
PHQ-9 HADS
124
What is the management of endometrial cancer?
total abdominal hysterectomy with bilateral salpingo-oophorectomy
125
When is the MMR vaccine given?
1 year and 3 year+4months
126
What are notifiable disease?
Scarlet fever, measles, rubella, mumps, TB
127
what are the features of a patients voice wo has schizophrenia?
third person auditory hallucinations running commentary hearing her own thoughts aloud
128
What in a MSE assessment would you consider a patient to have schizophrenia?
appearance - flamboyant and unusual speech - pressurised Thought disorder/grandiose delusion
129
What are the risk factors for IUGR?
Pre-eclampsia smoking previous IUGR
130
What investigations would you use to assess the fetus?
cardiotocography, ultrasound of amniotic fluid volume
131
Who is involved in the MDT for a consultant led patient?
Obstetrician Midwife Neonatologist
132
What would be a cause for raised creatinine and urea?
Renal tract obstruction
133
what do opioid medications act on?
Mu receptors
134
what is acidosis?
pH below 7.35
135
What is seen on a GBS CSF?
high protein and raised opening pressure
136
How do you determine if asthma is well controlled?
- pattern of salbutamol use - persistence of sx -wheeze, nocturnal diurnation - previous hospital admissons due to asthma
137
what are the investigations and TX for GBS?
Electromyography IVIG and physio
138
What are types of peripheral neuropathy?
Charcot marie tooth Mitochondrial disorders
139
what are 2 causes of GBS?
Camylobacter jejuni Epstein barr virus
140
What blood tests are performed for alcohol dependence?
GGT raised MCV raised
141
What are 4 things you would ask in a HX to a PX presenting with diarrhoea?
- presence of blood or mucus - Abdominal pain - Travel -Weight loss
142
What Ix would be performed for diarrhoea?
FBC ESR Stool culture Faecal calprotectin
143
What is seen on a CT with a person with Parkinsons?
Normal CT
144
What are the causes of weight loss and weakness in elderly people?
Frailty Malignancy Ageing HF
145
What is seen histologically for Ulcerative colitis?
Mucosa layer only Crypt distortion, abscess
146
What is deontology?
doing what is morally right, based on principles, rules, or duties, rather than focusing on the consequences of the action.
147
What i seen microscopically for crohns?
Inflammation of all layers, granulomas and goblet cells
148
What is seen microscopically for coeliac disease?
crypt hyperplasia and villous atrophy
149
What is passivity phenomena?
Bodily sensations been controlled by an external influence
150
What is delusions of persecution?
where first a normal object is perceived then secondly there is a sudden intense delusional insight into the objects meaning for the patient
151
What is the criteria for antibiotics for otitis media?
- Sx for 4 or more days -systemically unwell - Immunocompromised -<2 with bilateral otitis media -acute otitis media with perforation
152
What are the Sx for mastoiditis and what is the management plan?
- Tenderness behind the ear -ear sticking out more prominently Clinical emergency - urgent same day referral
153
What is seen in nephrotic syndrome and what are the main causes?
- proteinuria -hypoalbuminaemia -oedema Caused by minimal change disease
154
What is seen in nephritis syndrome?
Haematuria proteinuria
155
What causes nephritic syndrome?
Henoch schonlein purpura Post strep infection - weeks after IgA nephropathy - days after
156
What is the drug used to treat Neonatal abstinence syndrome for cocaine?
IV phenobarbital
157
What is screened for at the 20 week scan?
- edwards Patau anencephaly Gastroschisis cleft lo[ bilateral renal agenesis
158
What are the female indications for early fertility referral?
Over 35 Amenorrhoea or oligomenorrhoea Previous abdo/pelvic surgery Previous sti/PID
159
What are the reasons for early fertility services in men?
- previous urogenital surgery Previous sti varicocele Two abnormal semen results
160
What are the causes of polyhdraminios?
idiopathic Diabetes Multiple pregnancy Foetal anaemia Diaphragmatic hernia
161
Causes of oligohydraminois?
Pre-eclampsia post term ACE-inhibitors PROM renal genesis
162
What is a complete molar pregnancy?
empty egg being fertilised -XX Snowstorm appearance
163
What is an incomplete pregnancy?
XXX fertilisation of one egg and one sperm duplicated or 2 sperm
164
What is the definition of PPH?
>500ml of blood loss following the delivery of the baby Minor <1000 Major is >1000 (moderate if 1000-2000) or severe if >2000
165
Common causes of PPH?
Tone Placenta retention Tear- trauma Thrombin
166
What is the FIGO staging?
1 - confined to uterus 2 - carcinoma extends to the cervix but not beyond the uterus 3-carcinoma extends beyond uterus to ovaries 4-carcinoma involves bladder or bowel
167
What is Meig's syndrome ?
Complication of ovarian cysts - Ovarian fibroma, ascites and plural effusion - Do CXR
168
What livery blood is raised in pregnancy?
ALP - increased burn turnover
169
What us the fever PAIN score?
- fever pus on tonsils attended within 3 days inflamed tonsils no cough
170
What is the centor criteria?
Tonsillar exudate anterior cervical lymphadenopathy fever of 38 degrees absence of cough
171
What is the management of endometriomas - if fertility is a priority?
Laparoscopic ovarian cystectomy with excision of the cyst wall
172
What is a staggered overdose?
First and last drug 1 hour apart
173
What is the treatment for pneumocystis pneumonia?
co -trimoxazole
174
What is the order of preference for women for STI testing?
endocervical, vulvovaginal, first catch urine
175
What is the Black report?
1980 - inequalities in health - artefact health or social selection materialist/structuralist cultural/behavioural
176
What are the signs and symptoms of a primary HIV infection?
- fever -llymphadenopathy myalgia
177
What are longstanding HIV Sx?
Can be asx then progressive immune dysfunction can cause - TB or pneumocystis pneumonia meningitis malignancy
178
What are the investigations for HIV?
HIV antibody test - IgM or IgG p24 antigen
179
What is the treatment for HIV?
combination antiretroviral therapy
180
What are the opportunistic infections for HIV?
pneumocystis pneumonia Candidiasis CMV Kaposi's sarcoma - caused by HHV8 (multiple purple/brown lesions on skin) lymphoma Cervical cancer - cant clear HPV
181
What is the difference between a simple and complex febrile seizure?
A simple seizure is <15 minutes - - generalised seizure A complex seizure >15 minutes - focal seizure
182
What is chvostek's sign?
hypocalcaemia tap facial nerve to get twitching of nerve
183
What is hoovers sign?
weakness of voluntary hip extension - feel pressure under heel of affected leg
184
when should you start an alendronic acid?
– ≥65 and on long-term steroids should be offered bone protection even without a DEXA scan
185
what is the function of nimodipine?
21d course of nimodipine is used to prevent vasospasm as it targets the brain vasculature
186
What is the management of impetigo?
- Hydrogen peroxide 1% cream - if systemically well - Fusidic acid -Oral flucloxacillin
187
What is the management of chicken pox exposure in pregnancy?
- check varicella antibodies - if none give varicella immunoglobulin immediately -Oral aciclovir if rash
188
What is a grandiose delusion?
idea that the person themselves are powerful/crucially important beyond truth
189
What is need?
An ability to benefit from an intervention
190
What is comparative need?
Comparison between severity, range of intervention and cost - screening resources for HPV in an affluent area compared to low socioeconomic area
191
What is a health needs assessment?
A systematic approach to reviewing health issues affecting a population and what changes are required.
192
How would you evaluate health services?
DONABEDIAN - assessment whether service achieves its objectives - structure- staff, buildings, equipment (number of ICU beds per 1000 population) -process - number of prescriptions/ screening -outcome - mortality rate
193
what is relative risk?
risk in exposed group over risk in unexposed group
194
What is attributable risk?
How much of the risk is actually due to a certain risk factor
195
what is an epidemiological study and give a pro and a con ?
A study looking at trends in data at a population level += prevalence and correlation , readily available data -= doesnt show causation
196
what is a cross sectional study and give a pro and con?
looking at a specific disease and collects data on them at defined points of time. += Quick and cheap -=reverse causality and recall bias
197
What is a case control study and what is a pro and con?
A group of people with a disease and a group of people without who are the same sex/age and look at associations and risk factors. +=good for rare outcome -=Prone to bias, difficult to find appropriate control group
198
what is a cohort study and what is a pro and con?
Prospective study that has a group of people with an exposure and outcome in mind. follow them over time += causation, lower chance of bias -=takes a long time, large sample
199
What is the epidemiological assessment approaches? (assessment to assess health needs)
- defines size of problems, population, services available += uses existing data/ provides data on disease incidence and mortality -= doesn't consider felt need
200
What is the comparative approach?
2 demographically different services compared += quick and cheap -= difficult to find comparable population
201
What is a corporate approach?
- Asks the population what their health needs assessment are - focus groups/meetings += based on felt and expressed need/wide range of views -= difficult to distinguish need from demand/ bias by dominant personalities.
202
What is the treatment for opioid NAS?
Morphine
203
what is the ICD 11 criteria for opioid misuse?
A harmful pattern of use is evident over a 12 month period or at least 1 month if use is continuous. - persistent desire to cut down -using larger amounts over a longer period thean was intended -a lot of time obtaining, using -craving -failure to work, duties at home
204
What is kallman?
xlinked recessive - delayed puberty - hypogonadism -anosmia
205
What is klinefelter?
47xxy Taller Gynaecomastia small testes high gonadotrophin low testosterone
206
What aspects are assessed in the bishop score?
position consistency effacement dilation fetal station
207
When is the palmar grasp?
6 months
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When is the pincer grip?
9 months
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Sit without support?
6 months(9 month referral)
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What is the management for COPD, steroid responisve (asthma Sx)?
SABA or SAMA as required Then add LABA and ICS Then add lama
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What is the management for COPD, non steroid responsive ?
SABA or SAMA then LABA and LAMA Then add ICS
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What are the features of steroid responsive COPD?
History of asthma / atopy - Bloods: Eosinophilia - Diurnal variation of PEFR of 20% or more or FEV1 variation day-to-day of 400ml
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what is zopiclone?
a gaba agonist - used for sleep
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What is otitis externa?
infectious caused by staphylococcus aureus/allergies/swimming Sx - itch/pain/discharge Tx -topical abx
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What is ramsay hunt syndrome?
caused by reactivation of vzv in ganglion on 7th nerve - auricular pain -facial nerve palsy -rash around ear Tx - aciclovir and corticosteroids
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Difference between conduct disorder and oppositional defiant disorder?
oppositional defiant towards authorative figures but still does well at school (conduct is more severe, affects social problems)
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What causes horizontal diplopia?
CN 6
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What causes vertical diplopia?
CN 4
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What is the romberg test?
assess balance and proprioception
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When do you review a benign murmur?
1 month
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How do you measure small for gestational age?
Abdominal circumference less than 10th centile for gestation
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What changes are there in von willerbands disease?
prolonged bleeding time APTT may be prolonged factor 8 levels may be reduced
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What is the typical blood picture for disseminated intravascular coagulation?
low platelets low fibrinogen raised PT and APTT
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What is seen in haemophilia?
only prolonged APTT
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what should be monitored if a patient is on venlafaxine?
Blood pressure
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What is seen on biochem for a pateint with anorexia?
low magnesium, phosphate,calcium high cortisol and high cholesterol and high growth hormone low sex hormones metabolic alkalosis
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What are the side effects of TCAs?
dry mouth blurred vision constipation urinary retention
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When can expectant management be performed for an ectopic pregnancy?
An unruptured embryo 2) <35mm in size 3) Have no heartbeat 4) Be asymptomatic 5) Have a B-hCG level of <1,000IU/L and declining
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When is the management for ectopic surgical?
Size >35mm Can be ruptured Pain Visible fetal heartbeat hCG >5,000IU/
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What is the management for nausea and vomiting in pregnancy?
antihistamines: oral cyclizine or promethazine oral ondansetron (risk of cleft palate)or metoclopramide - only used for 5 days
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What is a APH?
Antepartum haemorrhage is defined as bleeding from the genital tract after 24 weeks pregnancy, prior to delivery of the fetus
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What bit does CP affcet in spastic type?
Upper motor neurones
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What does CP affect in dyskinetic?
basal ganglia and substantia nigra
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What bit does CP affect in ataxic?
cerebellar
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what are the Sx of Downs syndrome?
epicanthal folds single palmer crease flat face hypotonia small low set ears
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What is the first line test for CMPA?
skin prick/patch testing
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What is the long term management for CMPA?
follow up in allergy clinic Histamines
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What is the first line investigation for PROM?
Speculum examination - poo; of fluid in posterior vaginal fornix
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What are the risk factors for incontinence?
Pregnancy obesity previous deliveries Increasing age
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What are non pharmacological ways to prevent falls?
Increased salt intake Fluids -stay hydrated Get up slowly
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What are causes of pneumonia?
Streptococcus pneumonia Haemophilus influenza Mycoplasma pneumonia- atypical
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What are the signs and symptoms of pneumonia?
a cough with sputum dyspnoea fever chest pain
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What are the oxford stoke classification?
Total anterior circulation - unilateral hemiparesis, homonymous hemianopia, dysphasia Partial - 2 of the above Lacunar - unilateral weakness, pure sensory, ataxic Posterior circulation infarcts - cerebellar syndromes/LOC/ homon hemi
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What is lateral medullary syndrome?
Posterior inferior cerebellar artery - wallenberg ipsilateral facial pain and temp loss + horners contralateral limb pain and temp loss ataxia and nystagmus
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What is webers syndrome?
ipsilateral 3 nerve palsy contralateral weakness
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What is the definitive diagnosis for a TIA?
Specialist referral within 24 hours for a diffuse weighted MRI showing ischemia
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What are indicators of a poor prognosis of schizophrenia?
- strong family history gradual onset Low IQ social withdrawal lack of obvious precipitant
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What are the risk factors for schizophrenia?
Black, migration, urban environment, cannabis , FHx, male
249
What are 3 types of psoriasis?
- plaque psoriais -guttate psoriasis -pustular
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Lifestyle changes for psoriasis?
- smoking cessation reduce alcohol
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What is first line management for psoriasis?
potent corticosteroid and vitamin D analogue
252
What causes diabetic foot disease?
peripheral neuropathy - loss of sensation PAD
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How is neuropathic pain managed?
TCa pregabalin gabapentin
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What is osteomyelitis?
infection of the bone mc cause is staph aureus or salmonella if sickle cell disease
255
What is the investigation and management for osteomyelitis?
MRI Flucloxacillin
256
What are the risk factors for sleep apnoea?
Obesity acromegaly marfans large tonsils
257
What is the assessment and management for obstructive sleep apnoea?
Epworth sleepiness scale CPAP
258
What is intussusception?
invagination of one portion of the bowel into the lumen of the adjacent bowe
259
What are the stages of CKD?
stage 1 (G1) – above 90ml/min stage 2 (G2) – 60 to 89ml/min, stage 3a (G3a) – 45 to 59ml/min stage 3b (G3b) – 30 to 44ml/min stage 4 (G4) – 15 to 29ml/min stage 5 (G5) – 15ml/min,
260
what is AKI stage 1?
Increase in creatinine to 1.5-1.9 times baseline Reduction in urine output to <0.5 mL/kg/hour for ≥ 6 hours
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What is AKI stage 2?
Increase in creatinine to 2.0 to 2.9 times baseline Reduction in urine output to <0.5 mL/kg/hour for ≥12 hours
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What is AKI stage 3?
Increase in creatinine to ≥ 3.0 times baseline Reduction in urine output to <0.3 mL/kg/hour for ≥24 hours,
263
What is AKI?
Increase in serum creatinine by >26.5 mmol/l within 48 h, or Increase in serum creatinine > 1.5x the baseline within the last 7 days, or Urine output < 0.5 ml/kg/h for 6 hours
264
What fluids do you give in maintenance?
0.9% saline + 5% glucose
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What fluids do you give in resus and how much do you give?
0.9% saline 10ml/kg in <10mins
266
How do you calculate the replacement fluids?
dehydration x 10x weight
267
How do you figure out the percentage dehydration?
well weight- now weight divided by well weight times 100
268
What is the correct dose for administering insulin in DKA?
(0.1units/kg/hr)
269
what are the features of adenomyosis?
dysmenorrhoea menorrhagia enlarged, boggy uterus
270
when are the cervical screen?
25-49 every3 years 49-64 every 5 years
271
What are the tests for DDH?
Barlow test: attempts to dislocate an articulated femoral head - quickly adduct and push Ortolani test: attempts to relocate a dislocated femoral head - quickly abduct
272
What are the other signs for DDH?
symmetry of leg length level of knees when hips and knees are bilaterally flexed
273
what are the sx of lithium toxicity?
coarse tremor (a fine tremor is seen in therapeutic levels) hyperreflexia acute confusion seizure
274
What are the adverse affects of lithium?
nausea/vomiting, diarrhoea fine tremor weight gain
275
what is the definition of preeclampsia?
≥ 140/90 mmHg after 20 weeks of pregnancy, AND 1 or more of the following: proteinuria
276
2 causes of postural hypotension?
medications -antihypertensives, levodopa hypovolaemia
277
What tests do you do before giving Lithium?
ECG U+Es TFT
278
What is atypical depression?
eat more sleep more periods of happy
279
What electrolyte inbalance can be caused in DKA?
initially high potassium , then after insulin Tx can cause hypokalaemia
280
What is the difference between serotonin syndrome and neuroleptic malignant syndrome?
Serotonin syndrome - caused by SSRI's, MAOI - fast onset -hyperreflexia dilated pupils -tachycardia Neuroleptic - caused by antipsychotics - slower onset -days hyporeflexia rigidity normal pupils High CK -
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