A bit of everything Flashcards
What 4 questions can be asked to assess mental capacity?
Does the patient Understand the information relevant to the decision?
Can the patient Retain the information?
Can they use the information to Weigh up the options and make a decision?
Can they Communicate their decision to you?
What is DOLS?
Deprivation of Liberty Safeguards
DOLS are part of the MCA, the safeguards aim to ensure that people in care homes or hospitals who lack capacity are looked after in a way that has their best interests at heart
What is an IMCA?
Independent Mental Capacity Advocate = a legal safeguard for people who lack capacity
They represent people when there is no one independent of service –> e.g. no family members/friends
What is the ICD-10 criteria for depression?
Persistent low mood
Loss of interest
Fatigue or low energy
Give 5 physical symptoms of depression
Sleep disturbance
Unexplained aches/pains
Appetite change
Loss of libido
Give 5 psychological symptoms of depression
Continuous low mood
Feeling hopeless
Tearful
Guilty
What investigations might you do in someone with depression and why?
Bloods –> glucose, U&Es, LFT, TFT, Ca, FBC, ESR/CRP
Imaging if there are features suspicious of an intracranial lesion
Done to exclude any organic cause
Name a screening tool for depression that can be used in primary care
PHQ-9
How would you among mild-moderate depression?
Active monitoring
Low intensity psychological intervention –> IAPT, CBT
Encourage lifestyle changes such as exercise, smoking cessation and healthy diet
How would you manage moderate-severe depression?
High intensity psychological intervention
2. Anti-depressant –> SSRIs, SSNRI, NASSAs, TCA, MAOIs
Name 3 Selective Serotonin Reuptake Inhibitors (SSRIs)
Fluoxetine
Citalopram
Sertraline
Name a Selective Serotonin-Norepinephrine Reuptake Inhibitor (SSNRI)
Duloxetine
Venlafaxine
Name a Noradrenaline and specific serotogenic antidepressants (NASSAs)
Mirtazapine
Briefly describe section 2 of the mental health act
Admission for assessment –> allows compulsory admission for up to 28 days for assessment
Briefly describe section 3 of the mental health act
Admission for treatment –> allows compulsory admission for up to 6
months for treatment
Briefly describe section 135 of the mental health act
A magistrate can authorise forced entry into a property where it is believed that a person is suffering from a mental health disorder
Briefly describe section 136 of the mental health act
Used by police to take someone suffering from a mental health disorder form a public place to a place of safety
Give 4 physical signs of anxiety
Restless
Difficulty falling asleep due to racing thoughts
Dizziness
GI Disturbance –> Nausea, diarrhoea, constipation
Increased HR, BP and sweating
Muscle tension
Shortness of breath
Give 3 psychological symptoms of anxiety
Excessive worry
Uncontrollable racing thoughts
Difficulty concentration due to agitation or racing thoughts
Sense of dread and fearing the worst
Feeling tense and nervous and unable to relax
Rumination = thinking about bad experiences over and over again
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148
Q
Name 3 possible causes of anxiety
Name 3 possible causes of anxiety
Family history
Female
Traumatic events
Other mental health problems
Chronic illness
Medications –> antidepressants, corticosteroids, OCP
Menopause
What is generalised anxiety?
Regular or uncontrollable worries about many different things in everyday life
- Subjective experience of nervousness
What is social anxiety?
Experience of extreme fear or anxiety triggered by social situation (parties, workplaces, or everyday situations where you have to speak to a different person)
What is a panic disorder?
Having regular or frequent panic attacks without clear cause or trigger
What are the characteristic features of panic disorders?
crescendo of the anxiety usually resulting in an exit from the direction
Somatic symptoms –> palpitations, sweating, trembling,SOB, chest pain, dizziness
Secondary fear of dying/losing control
What is a phobia?
Extreme fear or anxiety triggered by a particular situation
- HAve anticipatory features
Give 2 examples of phobia
Agoraphobia = crowds, public places, leaving home
Claustrophobia = small, enclosed spaces
Arachnophobia = spiders
Social phobia
What are the characteristic features of PTSD?
Hyperarousal –> persistently heightened perception of current threat
Avoidance of situation/activities
Emotional numbing
Re-experiencing –> flashbacks, nightmares
Describe the treatment of anxiety
Psychoeduction, sleep hygiene, self guided CBT, relaxation techniques
CBT
Pharmacological treatments
What is included in a MSE?
Appearance and behaviour
Speech
Mood and Affect
Thought
Perception
Cognition
Insight
What formula is used to work out how many units of alcohol are in a drink?
Strength of drink (%ABV) X Volume (ml) / 1000
Name 4 possible alcohol withdrawal medications and how they work
Acamprosate –> relieves cravings- NMDA receptors antagonist
Disulfiram –> make you suffer when drinking - inhibits aldehyde dehydrogenase
Naltrexone –> block opioid receptors in the brain
Pathophysiology of DKA
- Blood glucose raised due to peripheral insulin deficiency
2.Causes a rise in glucagon further raising the blood glucose
3.Leads to an accelerated breakdown of adipose tissue into free fatty acids which oxidise into ketones.
4.Hyperglycaemia and glycosuria lead to osmotic diuresis = dehydration
Features of DKA
> 3mmol/L
<Ph 7.35
>blood glucose 11mmol/L
What is raised in CAH?
17 hydroxyprogesterone
What are the features of CAH?
Increased androgens so virillisation of genitalia - clit hypertrophy
Precocious puberty
Early development of pubic hair
Salt wasting crisis
Hypokalaemia
Hypernatraemia
Metabolic acidosis
What is androgen insensitivity syndrome and the sx ?
46 XY
- Primary amenorrhoea
Undescended testes
Little or no pubic hair
where is wernicke aphasia?
What would it sound like?
superior temporal gyrus
Fluent but no comprehension
What is Broca’s aphasia?
Inferior frontal gyrus
Not fluent but comprehensive
What is BV and what is seen microscopically?
Overgrowth of gardnerella vaginalis
Produces aerobic lactobacilli
Clue cells
What and when are the tests for Downs?
Combined test at 11-14 (raised nuchal translucency, raised B-HCG, low PAPP-A)
Quadruple test 15-20 weeks ( Low Alpha feto protein, low unconjugated oestriol,, raised HCG and raised inhibin A)
Chorionic villious sampling - 10-12 week
Amniocentesis - 15 -20 week
Explain the menstrual cycle?
Follicular - FSH slowly rises and causes follicles to mature.
Maturing follicles produce oestrogen (oestrogen inhibits FSH) as the follicles mature, more oestrogen is produced until there is a peak which causes LH surge which causes ovulation. LH maintains corpus luteum. Corpus luteum produces progesterone and oestrogen which maintains and causes proliferation of the lining. Corpus luteum breaks down causing menstruation.
When should a breast referral be made?
Over 30 with an unexplained breast lump with or without pain
Over 50 with unexplained nipple changes
Over 30 with an unexplained lump in axilla
what are the first rank symptoms of schizophrenia?
third person auditory hallucination
Passivity phenomena
Delusion of perception
Thought disorders
What is sensitivity?
Proportion of the people who have the disease that were correctly identified.
What are the features of opioid misuse?
constricted pupils
drowsiness
rhinorrhea
Tremor
What is specificity?
Proportion of people who dont have the disease that were correctly excluded from the test
What is the cause of premature neonate RDS?
Deficient surfactant from T2 pneumocytes due to prematurity causing alveolar collapse. The baby will have fluid in their lungs during birth, when they take their first breath, the surfactant sould decrease the surface tension so the alveoli dont collapse. No surfactant = collapse
what is egalitarian?
Everyone is provided with all the necessary care
What is maximising?
An act is evaluated solely on its consequences
what is cyanosis?
more than 5g/dl of deoxygenated blood
what are the red flags for a CT <1 hour?
Vomiting more than once, GCS 13 on initial assessment, focal neuro, post traumatic seizure
What is syphillis?
treponema paliidum - sprochete bacterium
What are the features of primary syphillis?
chancre, local non tender lymphadenopathy
features of secondary syphillis?
generalised maculopapular rash, codylomata lata, alopecia
Features of tertiary syphillis?
neurosyphilis, cardiogenic
Investigations for syphillis?
VDRL, PCR/TPPA
TX for syphillis?
Benzathine penicillin G
What is the complication after ABX for syphillis?
Jarisch herxheimer reaction
what is the Mcroberts manouver?
hips and knees are flexed and abducted. provides a posterior tilt lifting pubic symphysis up
Rf for shoulder dystocia?
high maternal BMI
Prolonged labour
Gestational diabetes
Risk factors for GORD?
Hiatus hernia
Obesity
FHx of GORD
Downs
What are the symptoms of Brown sequard cord compression?
Hemisection
Ipsilateral corticospinal +DCML
Contralateral - spinothalmic
Treatment for cord compression?
Dexamethasone and surgical decompression
Symptoms of optic neuritis?
Decreased unilateral visual acuity
Poor discrimation of colour
Eye pain on movement
scrotoma
What is seen on CSf for bacteria?
cloudy, low glucose, high protein, polymorph WC
What is seen on CSF for virus?
clear, normal protein, lymphocytes
what is cerebral palsy?
a chronic disorder of movement and posture due to a non progressive brain abnormalities occurring before the brain has fully developed.
Toxicoplasmosis infection features? and TX
IUGFR, enceph
Pyremethamine and sulfadazine
Rubella infection features? Foetus and TX
Blueberry muffin rash, SNL, congenital cataracts
HSV foetal infection features? and Tx
encephalopathy
IV aciclovir
CMV infection features and TX?
BM rash, vague
Tx IV ganyclovir
Shyphillis infection foetus features?
Kerasitis, frontal bossing, SN deafness
TX IV benzathine penicillin
RF for ectopic preg?
IUD
PID
Endometriosis
Previous ectopic
IVF
Pelvic surgery
RF for cord prolapse?
Polyhdraminos
Prematurity
Artifical rupture of membranes
RF for vasa praevia ?
Placenta praevia
Multiple pregnancy
Low birth weight
Rf for placenta praevia
Previosu placenta praevia
Previous Csection
Multople pregnancies
>35
Uterine surgery
Rf for placenta increta?
Previosu csection
Uterine surgery
Hx of placenta praevia
>35
RF for endometrial ca?
nullparity
early menarche
late menopause
obesity
PCOs
Diabetes
Vulval Ca RF
HPV
Lichen sclerosis
VIN
Immunosuppresison
Cervical cancer RF
HPV
Multiple sexual partners
smoking
High parity
HIV
Ovarian Ca Rf
BRCA 1
Early menarche
LAte menopause
Nulliparity
What are the symptoms of endometriosis?
Dysparaenia
Dysmenorrhoea
Dysuria
Pelvic pain
What is seen on a pelvic examination with someone who has endometriosis?
fixed retroverted uterus
Tender uterus
Nodules
What is biochemically seen in PCOS?
LH:FSH ratio - LH raised
Low sex hormone binding globulin
possibly raised prolactin and testosterone
What is biochemically seen in menopause and premature ovarian failure?
Raised FSH and LH
what is the most common type of endometrial cancer?
Adenocarcinoma
Advantage of transtheoretical model?
acknowledges individual steps of readiness
Gives an idea of time frame
Disadvantage of transtheoretical model?
not all people move through each stage
No social cues
People go forward and back
what are the features of tuberous sclerosis?
ash leaf spots
Infantile spasms
developmental delay
Retinal harmatomas
Autosomal dominant
What are the features of neurofibromatosis 1 ?
Cafe-au-lait spots
Axillary/groin freckles
Peripheral neurofibromas
Iris hamatomas
Scoliosis
Pheochromocytomas
What bacteria causes whooping cough?
Bordella pertussis - gram negtive coccobacillus
What immunisation is recommended for children with T1DM?
influenza
How do you calculate the APGAR score?
Colour - pink = 2, blue extremities =1, cyanosis = 0
Muscle tone - active movement =2, limb flection =1, flaccid
Reflex irritability - cries on stimulation = 2, grimace = 1
Pulse rate - >100=2 ,<100 = 1
Respiraotry effort - strong cry =2, weak = 1
what is the treatment for bacterial meningitis?
<3months= cefotaxime and amoxicillin
>3months - ceftriaxone
What is the kernig’s sign ?
Knees are flexed, a clinician extends the knee which cause resistance, pain or the knees wont flex
What is parkinson’s disease?
neurodegenrative disorder caused by degeneration of dopaminergic neurons within the substantia nigra.
What are the main features of parkinsons?
Bradykinesia
Rigidity
Tremor
What are other features of parkisnons?
mask like faces
drooling
Postural hypotension
What are causes of parkinsonism?
Parkinsons disease
Drug induced
Multiple system atrophy - Autonomic disturbance
Progressive supranuclear palsy - impairment of vertical gaze
What scoring system is used for prostate cancer?
Gleason
What are the causes of raised PSA?
BPH, prostate cancer, prostatitis
What LFT would be seen in prostate cancer?
Alkaline phosphate
What drug is given with levodopa and why?
Decarboxylase inhibitor and to reduce the peripheral breakdown of levodopa to reduce side effects
What are the features of brown sequard?
ipsilateral loss of fine touch, proprioception, vibration and ipsilateral hemiplegia
- contralateral loss of pain and temp sensation. Weakness below lesion
What causes otitis media?
Streptococcus pneumonia
Adenovirus
rhinovirus
what are the symptoms of pre-eclampsia?
Headache
papilledema
RUQ pain
hyperreflexia
Proteinuria
What are the high risk factors for pre-eclampsia?
DM
CKD
SLE/ALP
What are the moderate risk factors of pre-eclampsia?
first pregnancy
age 40 years or older
pregnancy interval of more than 10 years
body mass index (BMI) of 35 kg/m² or more at first visit
family history of pre-eclampsia
When should you take aspirin in pregnancy?
Take it from 12 weeks until birth
- 1 high risk or 2 low
what are the common effects of levodopa?
dry mouth
psychosis
postural hypotension
What is regularly taken with levodopa and why?
decarboxylase inhibitor - decreased peripheral breakdown of levodopa to reduce side effects