A Flashcards
Accurate
- indications and ocular side effects
Cystic acne, optic neuritis, dry eye, decreased night vision, transitory myopia
Amiodarone
Anti arrhythmic
Whorl keratopathy, optic neuropathy, photophobia
Blocks na/K channels which increase refractory period of myocardial cells
Estrogen
Pregnancy prevention
Optic neuritis. Dry eyes
Warfarin
Prevents clot formation
Retinal and subconjunctival haemorrhage (also seen in ginkgo biloba)
Digoxin
Congestive heart failure
Red/green defects, flickering/flashes of light, coloured spots, hazy dim vision
Bisphosphonate (alendronate)
Osteoporosis
Blurred vision, hyperaemia, anterior uveitis, episcleriris, scleritis
Plaquenil
Malaria, rheumatoid arthritis, lupus
Bull’s eye maculopathy, corneal deposits
Prednisone (corticosteroid)
Lupus, rheumatoid arthritis, immune mediated conditions
Posterior subcapsular cataract, high iop
Antidepressants (Prozac)
Dry eye, blurred vision, mydriasis, ptosis, photophobia, diplopia, conjunctivitis
Topiramate (topamax)
Migraine and seizures
Acute myopia, bilateral angle closure glaucoma
Viagra
Erectile dysfunction
Bluish tinge to vision, NAION, macular oedema
Acetazolamide
CAI reduces HCO3- production = less AH production
Beta blockers - betaxolol, Timolol
Lowered camp = lowered AH, blocking of beta 1 = lowered cardiac output and rate
Acyclovir
Antiviral - specific for herpes simplex
Triple phosphorylation by thymidine kinase
Inhibits viral DNA synthesis
Tetracyclines
Antibiotics that inhibit across of tRNA to acceptor site on 30s ribosomal subunit
Hepatotoxicity
Macrolides
50s subunit
Beta lactam
Amoxicillin, carbapenim, cephalosporins
Prevent cross linking in cell wall synthesis by binding PBP
Glycopeptides (vancomycin)
Inhibits cell wall synthesis
Aminoglycosides
Gentamicin, neomycin
Bactericides, nephrotoxicity
Bimatoprost
PGA
increase MMPs = relaxation of ciliary muscle = remodelling ECM of ciliary muscle = increased uveoscleral outflow
Timolol, betaxolol
Beta blockers
Timolol cannot be used in asthma (beta 2 blockage = bronchoconstriction)
Blocks atp -> camp -> lowered AH production
CAIs
Acetazolanide
Decreased HCO3- = lowered AB
Nausea, vomiting, GI distress, weight loss, paraesthesia of hands and feet, depression
Physistigmine/neostigmine
Inactivated ACHE = strong miosis
Glaucoma treatment
Bradycardia, GI tract changes and increased secretions
Pilocarpine
Adie’s pupil, acute angle closure glaucoma
Piroxicam
Cox2 inhibitor
Aspirin
Mostly COX1 inhibitor, blood thinner
Ibuprofen
Cox1&2
