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Neuro Pharmacology > :) > Flashcards

:) Flashcards

0
Q

Morphine

A 
Mu agonist - inhibits GABA inhibition of descending pathway, blocks ca channels, blocks post synaptic k channels 
Causes miosis (pinpoint pupils)
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1
Q

Triptan

A

5-ht 1b and 1d agonist (stop production signal)

Tx: migraines

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2
Q

Methadone

A

Mu agonist

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3
Q

Oxycodone

A

Mu agonist

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4
Q

Heroin

A

Mu agonist, very lipophillic

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5
Q

Naloxone

A

Mu antagonist

Also naltrexone

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6
Q

Codeine

A

Partial mu agonist

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7
Q

Buprenorphine

A

Partial mu agonist

Other opioid receptor antagonists

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8
Q

Celecoxib

A

Selective cox 2 inhibitor

Cox 1 is normal physiologically

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9
Q

Tubocurarine

A

Nicotinic antagonist

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10
Q

Procaine
Tetracaine
Cocaine
(Pet co)

A

Ester type local anesthetics (more rapid metabolism than amide type)
Blocks sodium channels

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11
Q

Lidocaine
Bupivacaine
Ropivacaine
(Bladder)

A

Amide type local anesthetics
Block sodium channels
Lower pk drugs have more rapid onset because uncharged at physiologic ph

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12
Q

Phenylephrine

A

Sympathomimetic (alpha 1 agonist)
Used to dialate pupil (myriadsis)
Also reverses ptosis in horners syndrome

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12
Q

Cocaine

A

Ne and da reuptake inhibitor

Absence of pupillary dilation means horners syndrome

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13
Q

Amphetamine

A

Reverses axoplamic pump of ne reuptake (spits ne out)

Absence of response to cocaine or amphetamine means postganglionic horners

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14
Q

Atropine

A 
Bella Donna 
Muscarinic antagonist (parasympathetic)
15
Q

Pilocarpine

A

Muscarinic (parasympathetic ) agonist
Causes miosis
Used to treat narrow angle glaucoma

16
Q

Timolol

A

Beta blocker

Decreases aqueous humour formation

17
Q

Latanoprost

A

Prostaglandin derivative

Increases uveoscleral outflow (thru ciliary muscle)

18
Q

Acetylzolamide

A

Carbonic anhydrase inhibitor

Used to treat glaucoma and hydrocephalus

Neuro Pharmacology (1 decks)

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