9.1 - Male and Female Reproductive Tracts Flashcards

1
Q

Function of External Genitalia

A
  • protect internal genital organs
  • provide pleasure
  • allow sperm to enter body
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2
Q

External Sex Organs

A

1) Vulva

2) Mons Pubis
- fatty tissue that covers pubis bone
- sebaceous glands secrete pheromones

3) Labia majora - fleshy folds
- contain glands that produce lubricating secretions
- protect external genital organs

4) Labia minora - inside labia majora
- becomes engorged during sex
- highly vasculated

5) Urethra Orifus
- urethral opening (in front + above vagina opening)

6) Clitoris
- sensitive to sexual stimulation

7) Vaginal opening

8) Perineum - area bw vagina and anus

8) Vestibular apparatus
- secretes lubricant during sex

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2
Q

Internal Sex Organs

A

1) Vagina
- passageway for sperm to enter, menstrual blood to exit, and childbirth
- vaginal lining produce secretions to maintain moisture and pH
- surrounded by elastic tissue; enables stretching during birth

2) Uterus
- supports and nourishes fetus during pregnancy
- thick-walled

a. cervix: lower part of uterus

b. cervical os: opening of uterus
- allows sperm to enter and blood to exit
- protective barriers (guards uterine cavity from pathogens)

c. cervical lining
- produces mucous (barrier to sperm)
- during ovulation, mucous becomes thin and clear to increase risk of fertilization

3) Uterine/Fallopian tubes

4) Ovaries

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3
Q

Structures of the Uterus

A

1) Corpus - elastic
- allows fetus to grow
- fundus: upper part of uterus
- contracts to prevent haemorrhage
after birth

2) Uterine wall - 3 layers

  1. endometrium - inner layer
    - if fertilization does not occur, this sheds as blood
    - if fertilization occurs, it supports attachment of placenta
  2. myometrium - middle layer
    - contains smooth muscle (contracts during birth) ‘
  3. perimetrium - outer
    - provides structural support
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4
Q

Uterine/Fallopian Tubes

A
  • paired tube structures (extend toward each ovary)
  • inner layer: mucosal layer and cilia that helps transport oocyte to uterus
  • uterine wall contains smooth muscle to help push oocyte into uterus
  • ampulla: where fertilization occurs

Infundibulum
- funnel structure at end of tube
- has fimbriae (that capture oocyte)

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5
Q

Ovaries

A
  • connected to each side of uterus
  • produce estrogen and progesterone
  • site of oogenesis: where immature oocytes produce and mature

Follicles
- contains oocyte and releases them during ovulation
- follicle development occurs cyclically with hormone signalling

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6
Q

Human Eggs

A
  • females are born with all of the oocytes they will have in their lifetime

Atresia: natural process of cell-degeneration where oocytes degenerate before birth

  • only small amount of oocytes (400) mature and release during ovulation
  • they freeze in meoisis I which makes them vulnerable to mutations
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7
Q

Menstruation Cycle

A

Menarche
- 1st period
- indicates puberty onset

Menopause
- end of reproductive years
- oocytes can no longer response to maturation signals

Hormone Regulation
- hypothalamus releases gonadotropin-releases hormone
- GnRH promote anterior pituitary gland to secrete LH and FSH
- LH and FSH stimulate ovaries to produce estrogen and progesterone

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8
Q

Female Cycles

A

1) Menstruation
- day 1
- decline progesterone and estrogen
- corpus luteum degenerates
- endometrium sheds
- blood contains fibrinolysis to prevent clotting

2) Follicular (proliferative)
- day 6
- estrogen promotes regeneration/thickening of endometrial lining
- ↑ FSH = develops follicles

3) Ovulation
- day 14
- high estrogen = LH surge
- oocytes are released and captured by fimbriae

4) Luteal (secretory)
- rupture follicle become corpus luteum
- endometrium thickens
- NO fertilization = corpus luteum degenerates = ↓ progesterone and estrogen
- fertilization = embryo releases human chorionic gonadotropin which maintains corpus luteum and high progestersone

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9
Q

Hormonal Regulation of Menstrual and Ovarian Cycles

A

1) Hypothalamus release GnRH which stimulates the anterior pituitary to release FSH andLH

2) FSH stimulates follicle development and produce estrogen

3) High estrogen causes a surge in LH
- LH is needed for oocyte maturation

4) 1 Follicle reaches full maturation and gets release during ovulation
- remaining follicles undergo atresia

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10
Q

Ovarian Follicular Changes

A

During Ovulation
- mature graafian (mature) follicle presses on ovarian surface = rupture = releases 2ndary oocyte
- surge of LH weakens ovarian wall (triggers enzymes that break it down)

After Ovulation
- remainders of ruptured follicle become the corpus luteum (leutinization)
- cells in follicle (granulosa and thesa) undergo changes
granulosa: granulosa lutein
thesa: thesa lutein
- these cells produce estrogen and progesterone which suppresses GnRH and thus reduces release of LH and FSH

AFTER release of 2ndary oocyte
- oocyte is captured by fimbriae and enters ampulla

IF fertilization occurs:
- corpus luteum produces progesterone and estrogen

Fertilization does NOT happen:
- corpus luteum degenerates into corpus albicans
- progesterone ad estrogen levels drop (thats what maintains uterine lining)

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11
Q

Male External Reproductive Structures

A

1) Penis
- root: anchored to the body and provides stability
- Shaft: channel for urinary and reproductive tracts
- Glans Penis: tip containing urethral orifus
- Corona: rim around glands
- Foreskin: covers glands

2) Scrotum
- skin and muscular tissue that encloses the testes
- provides optimal temp regulation for sperm
- Dartus muscle: retains heat
- Cremastur muscle: surrounds spermatic cord (brings tests close to body for warmth or further for cooling)

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12
Q

Erectile Tissue

A

1) Vascular Sinoids
- engorge with blood (mediated by PSNS) and cause an erection

2) Corpora Cavernosa
- provide rigidity during erection
- paired structure on back side

3) Corpus Spongiosom
- prevents urethra from compression during erection
- ventral (side)

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13
Q

Testes

A
  • in the scrotum

Spermatogenesis: production of sperm in seminiferous tubules

  • Sertoli cells: support and nourish developing sperm
  • Leydig: produce testosterone
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14
Q

Seminiferous Tubules

A
  • where spermatogenesis occurs

Sertoli Cells
- provide support and nourishment for developing sperm cells
- release signals for sperm development
- form blood barrier in testes

Leydig Cells
- produced testosterone (androgen that stimulates sperm production)

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15
Q

Hormonal Regulation of Spermatogenesis

A

1) GnRH is released by hypothalamus and stimulates anterior pituitary gland to secrete FSH and LH

2) LH stimulates Leydig cells to produce testosterone

3) FSH stimulates sertoli cells to release androgen binding protein which binds testosterone, concentrates it (makes ideal environment for sperm production)

16
Q

Spermatogenesis

A

Spermatogonia
- outer layer of seminiferous tubes
- produce primary spermatocytes when dividing by mitosis

  • Meiosis 1: primary spermatocytes divides into secondary spermatocyte
  • Meiosis 2: secondary spermatocyte becomes spermatids (immature and non-motile)

Spermiogenesis
- spermatids (non-motile) develop flagella for motility

Maturation and Release
- primary spermatocyte gives rise to 4 mature sperm cells
- once mature, sperm are released into seminiferous tubules and transported to epididmyis for further maturation

17
Q

Internal Male Reproductive Structures

A

1) Epididmyis (storage)
- storage site for sperm
- where they become motile and fertile

2) Vas Deferens (transport)
- tube that transports sperm from epididymis to ejaculatory ducts
- (has smooth muscle layer) that contracts during ejaculation

3) Seminal Vesicles (support/nourish)
- nourish sperm
- buffer vaginal acidity
- contain prostaglandins: that thin cervical mucous and cause peristalsis to transport sperm to the egg

4) Prostate Gland (make viable)
- produces acidic, milky fluid (most of sperm)

Adds:
PSA - for sperm motility
Citric Acid - for sperm energy/metabolism
ZInc/Antimicorbial - reduce infxns

5) Bulbourethral Gland (lubricate)
- secrete pre-ejaculate fluid
- lubricate urethra to facilitate sperm passage

6) Urethra
- transports urine form bladder to out of body
- Urethral sphincter: prevents simultaneous release of semen and urine
- delivers sperm from ejaculatory ducts to outside