9 - Obstruction Flashcards

1
Q

What are some non malignant causes of changes to urinary flow?

A
  • BPH
  • UTI
  • Urinary tract stone disease
  • Urological emergencies (urinary retention, acute loin pain, acute renal failure, systemic sepsis, spinal cord compression)
  • Urological trauma
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2
Q

What are causes of urinary retention?

A

Calculi

Pregnancy

BPH

Recent surgery

Drugs

Urethral strictures

Pelviureteric junction obstruction

Pelvic masses

Constipation

Inflammation

Neurogenic disorders

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3
Q

How does acute ureteric obstruction present, what is it usually caused by and how do we diagnose it?

A
  • Renal colic due to calculus
  • Acute severe flank pain radiating to groin
  • Can be pyonephrosis on top
  • Need plain CT or ultrasound
  • Emergency as can develop sepsis
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4
Q

How does chronic ureteric obstruction present, what is it usually caused by and how do we diagnose it?

A
  • Painless
  • Bi or uni lateral
  • Often found incidentally or during renal failure
  • Often due to external obstruction
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5
Q

What is the definition of obstructive uropathy?

A

Renal impairment due to bilateral or uni lateral ureteric obstruction, or high pressure chronic retention

It is a cause of high pressure chronic retention and can get hyperkalaemia as reflux back into kidneys

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6
Q

What is pyonephrosis?

A

Infection of the kidneys’ collecting system due to obstruction. Pus collects in the renal pelvis and causes distension of the kidney. It can cause kidney failure and sepsis so treat like septic patient

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7
Q

Apart from CT and ultrasound, how can we diagnose that a dilated kidney is due to obstruction?

A
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8
Q

What is the presentation of ureteric colic?

A
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9
Q

How can you treat ureteric obstuction?

A

Decompress if emergency as risk of sepsis and then one of these procedures

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10
Q

What is pelviureteric junction obstruction?

A
  • Often congenital but can present at any stage in life or be asymptomatic and found on imaging by hydronephrosis
  • Often loin pain worse after heavy fluid intake or alcohol
  • Laproscopic pyeloplasty
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11
Q

What is retroperitoneal fibrosis?

A

Fibrosis around the aorta that can pull the ureters in and cause an obstruction

Need to decompress, exclude malignancy and give immunosuppression

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12
Q

What is the difference between acute and chronic urinary retention?

A

Chronic can be painful when acute on chronic and can also be high pressure or low pressure

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13
Q

What is the definition of urinary retention?

A
  • Inability to voluntarily urinate
  • Acute urinary retention is the sudden and often painful inability to void despite having a full bladder
  • Chronic urinary retention is painless retention associated with an increased volume of residual urine
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14
Q

What are some causes of urinary retention in men and women?

A
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15
Q

How do we treat acute urinary retention?

A
  • Catheterise and record residual volume first
  • History
  • Exam e.g abdomen, DRE, genitalia
  • Urine Dip
  • Treat causes like constipation or alpha blocker for prostate issues
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16
Q

How should you treat someone with acute urinary retention due to issues with their prostate?

A
  • Alpha blocker
  • TWOC after 1-2 weeks of blocker
  • If fails do TURP
17
Q

What is the difference between high and low pressure chronic urinary retention?

A
18
Q

How should we manage chronic urinary retention?

A

High pressure: same as acute e.g catheterise etc, but cannot TURP so need constant catheter

Low pressure: TURP works in 50% but usually intermitten self catheterisation or long term catheter

Monitor overnight for post obstructive diuresis

19
Q

What is post-obstructive diuresis?

A

Prolonged urine production for at least two consecutive hours immediately following the relief of urinary retention. Can lrad to dehydration and electrolyte imbalance so might need fluids

20
Q

What are some ways of treating bladder stones?

A
  • Percutaneous suprapubic cystolitholapaxy
  • Open cystostomy
  • Lithotripsy
21
Q

What is prostatitis?

A

Inflammation of the prostate

Can cause obstrutction

22
Q

What are the main pathogens in Acute Prostatitis?

A

E. coli

Proteus

Staphylococcus

C. trachomatis

Neisseria gonorrhoeae

Bacteria can be pushed up when inserting a catheter and urine then no longer flushes bacteria back out

23
Q

What are general and local symptoms of acute prostatitis?

A

General:

  • malaise
  • rigors
  • fever

Local:

  • difficulty passing urine
  • dysuria
  • perineal tenderness
24
Q

How does prostatitis present on examination?

A

Rectal examination reveals a soft, tender and enlarged prostate

25
Q

How can you get Chronic Prostatitis?

A

Inadequately treated infection

Some antibodies can’t penetrate the prostate effectively

Recurrent prostatic and urinary tract infections

Occasionally asymptomatic

26
Q

How can you confirm chronic prostatitis?

A

Histological examination showing neutrophils, plasma cells and lymphocytes

Positive culture from a sample of prostatic secretion

27
Q

What is Non-Bacterial Prostatitis?

A

Most common type of prostatitis

Results in enlargement of the prostate

Difficult to identify bacteria but normally C. trachomatis - normally sexually active men affected

Fibrosis as a result of chronic inflammation

28
Q

What is Benign Prostatic Hypertrophy (BPH)

A

Detectable in nearly all men 60+

Non-neoplastic enlargement of the prostate gland

Can lead to bladder outflow obstruction

Can be related to levels of testosterone

Digital rectal exam - firm, smooth and rubbery

29
Q

What is the pathology with testosterone behind BPH

A

Testosterone is a androgen

5 alpha reductase converts testosterone → dihydrotestosterone

This can inflame prostate

30
Q

How does BPH present?

A
  • Difficulty starting to urinate
  • A poor stream
  • Dribbling postmictruition
  • Frequency and nocturia
31
Q

What can BPH lead to?

A
  • Acute urinary retention
  • Desperate urge to pass urine
  • Progressive bladder distension → chronic painless retention and overflow incontinence
  • CKD
32
Q

What treats BPH?

A
  • Alpha blockers - relax smooth muscle at bladder neck and within prostate
  • Finasteride (5a-reductase inhibitor) presents the formation of di-hydrotetosterone
  • Transurethral resection of the prostate (TURP) - widens the urethra