9 - Nutritional Elements + Requirements Flashcards
45 mL/kg/day
Water Requirements - Volume Status
DEHYDRATION
40 mL/kg/day
Water Requirements - Volume Status
POST-OPERATIVE
35 mL/kg/day
Water Requirements - Volume Status
EUVOLEMIA
30 mL/kg/day
Water Requirements - Volume Status
ELDERLY or CHF
AMINO ACIDS
Energy Source
4 kcal / gram
FAT
Energy Source
- *DEPENDS ON PRODUCT**
- percent does not Rise DIRECTLY*
10% = 1.1 kcal/mL
20% = 2 kcal/mL
CARBOHYDRATE
energy Source
3.4 kcal/gram
What is the GOLD STANDARD for
Estimating Energy Requirements?
INDIRECT CALORIMETRY
Harris-Benedict
Fixed kcal/kg/day
Mifflin-St Jeor
Penn State Uni Predictive equations
Healthy + Normal Nutrition Status
How many kcal/kg/day does
ASPEN & SCCM recommend?
energy requirements
20-25
kcal/kg/d
first determine if obese or not
use ACTUAL BODY WEIGHT
ILLNESS or METABOLIC STRESS
w/ BMI <30
How many kcal/kg/day does
ASPEN & SCCM recommend?
energy requirements
25-30
kcal/kg/d
use ACTUAL BODY WEIGHT
ILLNESS or METABOLIC STRESS
BMI >30
How many kcal/kg/day does
ASPEN & SCCM recommend?
energy requirements
11-14
kcal/kg
in combination with HIGH PROTEIN FEEDING
OR
Penn State / Mifflin-St Jeor Equation
uses Actual Body Weight
MAJOR BURN INJURY
How many kcal/kg/day does
ASPEN & SCCM recommend?
energy requirements
> 30
kcal/kg/day
use actual body weight
Fixed kcal/kg
Calculation used for ENERGY REQUIREMENTS
WEIGHT used for OBESE PATIENTS
Ranges are availble for
Both ABW & IBW
Confirm weight used to derive calorie range before using
During periods of inadequate protein or energy intake,
what type of CATABOLISM occurs FIRST?
MUSCLE CATABOLISM –> AMINO ACIDS
- *<75g** of skeletal muscle protein is catabolized to
- *supply AA precursors** for liver gluconeogenesis & energy production
Protein Depletion >20% of body stores will lead to:
VVV
Comprimised IMMUNE SYSTEM –> INFXN & DEATH
Mild Protein Depletion
Albumin > 3.0 g/dL
What are the DAILY PROTEIN REQUIREMENTS?
1.1-1.3
g/kg/d
Need Normal Renal & Hepatic Function
Use ACTUAL BODY WEIGHT, unless OBESE –> IBW if obese
Obesity hypocaloric feeding regimens require HIGHER protein amounts
- *Moderate** Protein Depletion
- *Albumin 2.5 - 2.9 g/dL**
What are the DAILY PROTEIN REQUIREMENTS?
1.3-1.5
g/kg/d
Need Normal Renal & Hepatic Function
Use ACTUAL BODY WEIGHT, unless OBESE –> IBW if obese
Obesity hypocaloric feeding regimens require HIGHER protein amounts
SEVERE Protein Depletion
Albumin < 2.5 g/dL
What are the DAILY PROTEIN REQUIREMENTS?
1.5-2
g/kg/d
Need Normal Renal & Hepatic Function
Use ACTUAL BODY WEIGHT, unless OBESE –> IBW if obese
Obesity hypocaloric feeding regimens require HIGHER protein amounts
Parenteral Sources of
PROTEIN
Amino Acid Solutions
Base Compounds solution = 3.5-20%
mis of essential + non-essential Amino Acids
- *Final concentration = 2.5-10%**
- *Central** concentration max of 10% // peripheral concentration max = 2.5-3%
Function of FATS
Nutritrient Requirements
Essential component of:
Cell membranes / padding organs / Insulation
Precursor of:
PROSTAGLANDINS
Esential Fatty Acids:
Linoleic & Linolenic Acids
Fat Deficiencies
Esential FA’s = Linoleic & Lonolenic Acids
Diffuse Dermatitis
CLOTTING = platelet aggregation
Diminished Would healing
Hemolytic anemia
Hepatic dysfunction
FAT REQUIREMENTS
% / Min / Max
30% of total kcal
as a starting point
Min = 5% of WEEKLY caloric intake from fat
to prevent essential FA deficiency
- *MAX = 60% of total daily calories**
- *<2.5g/kg/day**
Parenteral Source of FAT
Nutrient Requirements
Fat = Most Concentrated Energy Source
INTRALIPID FAT EMULSION
10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL, used in compounding 3in1 TPNbags only
SMOFlipid 20% =2 kcal/mL
Has fish oil + MCT + Olive Oil + Soybean Oil
theoretically should be less pro-inflammatory, but is not proven
Fat Infusion Considerations
DURATION // SPEED
- *Isotonic Solutions** may be given directly through Peripheral Vein
- *10% & 20%**
Run over:
12-24 hours
- do NOT infuse over:*
- *> 30 - 50 mg/kg/hr**
CONTRAINDICATIONS
of FAT INFUSION
Elevated
TG’s >300mg/dL
need to use less fat for patient, ~5% kca
EGG ALLERGY
- *PANCREATITIS DUE to HYPERtg’s**
- pancreatitis due to other things is FINE, only from HYPERtg’s is contraindicated*
When do FAT / CALORIC requirements
NEED TO BE ADJUSTED?
If patient is on:
FAT-BASED IV SOLUTIONS = PROPOFOL
has a lot of fat in it already.
Carbohydrate (Dextrose)
Caloric Conversion
3.4 kcal/gram
DEXTROSE
Protein
Caloric Conversion
4 kcal/gram
Protein
Fat
Caloric Conversion
10% Lipid Emulsion = 1.1 kcal/mL
20% Lipid Emulsion = 2 kcal/mL
- *Respiratory Quotient = RQ**
- *VCO2 / VO2**
What Values mean what?
Indirect Calorimetry
< 0.7 = UNDERFEEDING
Want to be ~ 0.82 - 0.85
> 1 = OVERFEEDING
Goal for:
NITROGEN BALENCE
N2 (in) - N2 (out)
N2 (in) = protein/6.25 (include both oral and IV protein)
N2 (out) = [UUN g/ml) x 24 hr urine volume (mL)] + 2-4 (insensible losses)
SLIGHTLY POSITIVE
Carbohydrate Requirements
Make up the
rest of the energy requirements
after accounting for calories from fat / protein
Usually:
45 - 65%
of total calories
- *Parenteral = Dextrose**
- *Enteral =** Sucrose / Fructose / Corn Syrup+Maltodextrin
Concentration / Max Infusion Rate
Dextrose Infusion Considerations
Dextrose
5-35%
of final concentration
Central Max = 35%
Peripheral Max = 10-12.5%
Max Infusion Rate:
3-5 mg/kg/min
MICRONUTRIENT
Nutrition Requirements
Must be added to PN
Amount depends on many factors:
Hepatic / Renal Fxn
Fluid / Cardiac Status
Prior Nutritional Status
Electrolytes are
DOSED BY WEIGHT
MVI-12
Contains the:
- *RDA of 12 Vitamins**
- *10 mL/d**
Some other products also contain RDA for
- *Vitamin K** - need to give seperately
- *10mg weekly** or 1.5 mg/day
What Additional Vitamins might need to be added?
FOR ALCOHOLICS
FOLATE + THIAMINE
- *Vitamin K** might need to be given seperately
- *10mg weekly** or 1.5 mg/day
Special Considerations for
SELENIUM
Excreted VIA KIDNEYS
Normal Need = 60mcg
- *Renal Failure/Disease**
- *HALF = 30 mcg**
- except for CRRT, use standard dose*
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Special Considerations for
TRACE ELEMENTS
ZINC
COPPER
MANGANESE
Chromium
urine / bile excretion
Selenium
kidney excretion 60mcg –> 30mcg
Iron
not normally required unless long term TPN
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Special Indications for ZINC
GI Fistula
Wound Healing
Zing –> 3-12mg/day ABOVE normal requirements
- ALSO:*
- *Increase DOSE (2.5-5mg normal) for RENAL patients**