9 Facial Plastics Flashcards
1 What are the layers of the skin from superficial to deep?
- Epidermis
- Basement membrane
- Dermis (papillary and reticular)
- Subcutis
2 What are the layers of the epidermis from superficial to deep?
- Stratum corneum
- Stratum lucidum
- Stratum granulosum
- Stratum spinosum
- Stratum basale
3 What are epidermal appendages?
Skin-associated structures including hair follicles, apocrine glands, sebaceous glands, and eccrine (sweat) glands
4 What is the predominant type of collagen in the basement membrane?
Type IV collagen
5 What are the three phases of wound healing? (▶ Fig. 9.1)
Inflammation, proliferation, and remodeling. Some authors also include hemostasis as the first phase.
6 What are four general categories of wound healing?
- Healing by primary intention: Two wound edges are brought together as the primary intention of the surgeon.
- Delayed primary healing: Two wound edges are not brought together immediately but are reapproximated and closed at a later time.
- Healing by secondary intention: A full-thickness wound where the edges are not reapproximated and the wound is allowed to heal by granulation and contracture
- Epithelialization: Occurs in partial-thickness wounds as epithelial cells migrate and replicate over the wound
7 What cell types are primarily involved in the inflammatory phase?
After vasoconstriction and subsequent vasodilation, polymorphonuclear neutrophils arrive and predominate for the first 24 to 48 hours after injury. Following this, monocyte migration occurs.
8 What cell type synthesizes collagen?
Fibroblasts
9 What cell type is responsible for wound contraction during healing?
Myofibroblasts containing microfilaments capable of producing contractile forces. These cells predominate the fibroblast population during the second week of wound healing.
10 What major events occur during the proliferative phase of wound healing?
- Re-epithelialization
- Neovascularization
- Collagen deposition
- Wound contraction
11 During which phase of healing are keratinocytes, fibroblasts, and endothelial cells recruited to the wound?
Proliferative phase
12 During the proliferative phase, which cytokine modulates angiogenesis and neovascularization?
Vascular endothelial growth factor (VEGF)
13 How does hyperbaric oxygen therapy encourage wound healing?
It promotes angiogenesis, fibroblast proliferation, leukocyte activity, and is synergistic with antibiotic therapy.
14 What is the predominant type of collagen in an early scar?
Type III collagen
15 What is the approximate tensile strength of a healing wound at 3 months?
50% of normal tissue
16 When is the remodeling phase of wound healing usually complete?
12 months
17 What are the tenets of Halsted?
- Gentle handling of tissues
- Aseptic technique
- Sharp anatomical dissection of tissues
- Careful hemostasis, using fine, nonirritating suture materials in minimal amounts
- The obliteration of dead space in the wound
- Avoidance of tension
18 How can local tissue factors impact wound healing?
Wound healing is compromised by any tissue effect that decreases oxygenation, increases infection risk, prolongs inflammation, delays neovascularization, or otherwise alters the normal process of healing. Examples include local infection, ischemia resulting from pressure necrosis (e.g., diabetic neuropathy, hematoma), alteration in tissue structure resulting from radiation therapy, locally destruc tive processes (neoplasia, wound desiccation).
19 What patients should be counseled about increased risk for postoperative infection or wound breakdown?
Patients with medical comorbidities, medications, or history of recent treatments, which alter the normal healing process or suppress the immune system. For example, patients who have undergone chemotherapy and radiation therapy, are taking immunosuppressants, or have diseases that affect the vasculature (e.g., peripheral vascular disease, diabetes, current smoker) are at increased risk for wound complications.
20 What are relaxed skin tension lines?
They are the lines of minimal tension on the skin. They run parallel to natural wrinkle lines and are usually perpendicular to the force of action of the underlying muscles of facial expression
21 What are some of the technique- and patient related factors that may lead to an aesthetically unacceptable scar?
- Patient variables: Diabetes, chronic steroid use, systemic vasculitis, vitamin deficiency, poor overall nutrition, chronic renal disease, wound infection, collagen vascular disease, sun exposure
- Technical variables: Failure to clean the wound adequately, excessive tension on epidermal sutures, step-off between wound edges, rough handling of tissue, prolonged suture retention, failure to orient incision parallel to relaxed skin tension lines, delayed wound closure
22 What are some of the performance differences between monofilament and braided suture?
Monofilament suture has “memory” and usually requires more knots to secure a tie.
Braided suture has more tensile strength but creates more resistance through tissue, induces a stronger inflammatory response, and is more likely to serve as a reservoir for microorganisms.
23 What type of surface contour is most favorable for wound healing by secondary intention? (▶ Fig. 9.2)
Concave surfaces
24 What are some surgical options for scar revision?
Excision and closure with straight line, broken geometric line, W-plasty, Z-plasty, or local flap; excision and placement of a skin graft
