9: calcitonin, erythro, vit d, parathyroid

Question 1

site of synthesis of calcitonin in the thyroid gland

Answer 1

parafollicular/C cells

Question 2

the primary function of calcitonin is the decrease phosphate & __ ___ and ____ cell synthesis and activity, thereby inhibiting bone resorption

Answer 2

plasma calcium

osteoclast

Question 3

clinically, calcitonin is used for the tx of ___ & ___

Answer 3

osteoporosis

paget’s

Question 4

site of synthesis for erythropoietin (2)

Answer 4

kidney

liver (FETUS)

Question 5

function of erythropoietin is to stim the development of ____

Answer 5

RBC

Question 6

erythropoietin controls secretion of hormones including (2):

Answer 6

sub P

thyroxine

Question 7

vit d is synthesized in the ___ for 25-(OH) D3 type and ___ for all types

Answer 7

liver

kidney

Question 8

chem class that vit d belongs to

Answer 8

seco-steroid

Question 9

1,25(OH)2D3 is related to the ___ and hydroxcholecalciferol/calcifediol is related to ___

Answer 9

kidney

liver

Question 10

vid d is TIGHTLY reg by the activity f the ____ in the kidney, major control is ____ hormone

Answer 10

1-a-hydroxylase

parathyroid

Question 11

vit d primarily functions to increase __ __ & __ ___

Answer 11

linear height

plasma calcium

Question 12

secondary function of vit d is to stimulate the __ ___

Answer 12

integumentary system

Question 13

two things that control secretion of vit d

Answer 13

plasma calcium

sunlight

Question 14

vit d deficiencies can be caused by these two things

Answer 14

sun shunning

strict vegetarian diet

Question 15

increased CVD risk
cognitive impairment
severe asthma (chidren)
some cancers
--these can all occur with a deficiency of:

Answer 15

vit d

Question 16

normal range of vit d

Answer 16

20-50 ng/ml

Question 17

considered a vit d deficiency

Answer 17

12 ng/ml

Question 18

parathoromone (PTH) both stimulates ___ & increases ____ synthesis (liver to kidney) via stimulating syth of 1-hydroxlase enzyme

Answer 18

growth

100% vit d

Question 19

PTH increases ___ ___ by stim osteoclast cell activity

Answer 19

plasma calcium

Question 20

most powerful hormone to increase plasma calcium & decrease renal reabsorp of phosphorus

Answer 20

pth

Question 21

PTH decreases __ __ by decreases renal reabsorp

Answer 21

plasma phosphorus

Question 22

the big 4 secondary functions of PTH are to increase ___, plasma ___, ___, and ___ response

Answer 22

metabolism
glucose
BP
immune

Question 23

PTH deficiencies: not getting enough ___ or primary ___ via tumor on parathyroid gland

Answer 23

vit d

hyperthyroidism