9: Anti-Doping Flashcards

1
Q

doping

A

administration of drugs intended for the outcome of enhancing performance
overseen by WADA

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2
Q

prohibited substances

A

each year list of prohibited substances released
included non approved substances and prohibited methods

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3
Q

substances prohibited at all times includes

A

anabolic agents
peptide hormones
beta-2 agonists
hormone and metabolic regulators
diuretics and masking agents

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4
Q

substances prohibited in competition

A

stimulants
narcotics
cannabinoids
glucocorticoids
beta blockers

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5
Q

prohibited methods

A

manipulation of blood = administration of reintroduced blood
chemical and physical manipulation = tampering with sample
gene and cell doping = the alteration of genome sequences

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6
Q

11 anti-doping rule violations (ADRV)

A

presence
use
evasion
whereabouts
tampering
possession
trafficking
administration
complicity
prohibited association
acts to discourage or suppress reporting

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7
Q

athletes whereabouts

A

must provide location details of out-of-competition testing
national registered testing pool (NRTP) is generally used for elite athletes so has much stricter whereabouts reporting requirements
filing failure = inaccurate or insufficient whereabouts information leads to not being able to be found for testing
missed test = athletes who are not available for testing during an allotted time slot
if there are 3 whereabouts failures within 12 months: noted as ADRV, potential 2 year ban

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8
Q

why people dope

A

individual = athlete has desire to win
team = squad instructed to use doping agents, facilitated by management team
accidental = returning an AAF without knowledge of using prohibited substance

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9
Q

attempts to avoid AAF

A

structured doping routines which enhance performance but provide negative sample
failure to provide sample
substituting doped sample with clean alternative

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10
Q

how to stay clean

A

send sample away for testing - expensive and time consuming
don’t take the supplement
buy certified products

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11
Q

certified products

A

informed is a strategy put in place by LGC to provide testing and certification of supplement products
process includes: product evaluation, evaluation of raw material, review of manufacturing facilities and procedures, auditing of suppliers and distribution channels
tested products free of contamination are then permitted to show the informed sport logo

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12
Q

measurement techniques

A

majority contaminants are small molecules
supplements are mixture of multiple ingredients
typically measured by liquid/gas chromatography-mass spectrometry

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13
Q

athlete biological passport (ABP)

A

in early 2000s scientific research started to uncover ‘patterns’ of biological markers which indicated blood doping
the ABP monitors selected biological variables over time that indirectly reveal the effects of doping
in 2009 ABP was launched which contained the haematological module
in 2014 a steroid module was added

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14
Q

blood doping

A

blood doping is the manipulation of blood to gain advantage
can be done through:
homologous transfusion
autologous transfusion
in/direct stimulation of blood cell production
synthetic oxygen carriers

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15
Q

dried blood spot analysis

A

quick and easy collection method - finger prick and blotting pad
multiple samples can be collected over time from athletes without disruption to training/competition

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16
Q

other analysis methods

A

exhaled breath
global metabolite analysis