8.2 Cell Respiration Flashcards
Oxidation and Reduction
chemical processes that always occur together b/c they involve the transfer of electrons from one substance to another
LEO GER
Loss Electrons Oxidation
Gain Electrons Reduction
Electron Carriers
substances that can accept and give electrons as required
often link oxidations and reductions in cells
Electron Carries in Cell Respiration
NAD - NADH
FADH - FADH2
Phosphorylation
the addition of a phosphate molecule to an organic molecule
Purpose of Phosphorylation
to make the molecule more unstable / more likely to react
“activates” the molecule
Exergonic Reaction
releases energy
Endergonic Reaction
absorbs energy
need to be coupled with exergonic reaction
Coupled Endergonic and Exergonic Reaction Example:
Glucose (to) Glucose-6-phosphate (with hydrolysis of ATP)
Glycolysis
1st step: Glucose to Glucose-6-phosphate (needs 1 ATP)
2nd step: Glucose-6-phosphate to Fructose-6-phosphate
3rd step: Fructose-6-phosphate to Fructose-1,6-bisphosphate (needs 1 ATP)
4th step: Fructose-1,6-bisphosphate to 2 Triose Phosphate
5th step: each Triose Phosphate to Glycerate-3-phosphate (yields ATP and NAD+ becomes NADH + H+)
Final Steps: G3P to Pyruvate
Net Yield: 2 ATP and 2 NADH and 2 Pyruvate
The Link Reaction (mitochondrial matrix)
pyruvate is decarboxylated and oxidized to form acetyl coenzyme A (NAD+ to NADH)
The Krebs Cycle (mitochondrial matrix)
2 decarboxylations and 4 oxidations
Products: 3 NADH, 1 FADH2, 1 ATP
Oxidative Phosphorylation / Chemiosmosis (inner membrane and intermembrane space)
final stage of aerobic respiration
ADP phosphorylated to produce ATP using energy released by oxidation
electron transport chain: NADH and FADH2 donate electrons to electron carriers - electrons passed from carrier to carrier - energy utilized to transfer protons inner membrane from the matrix into the intermembrane space - protons flow down the concentration gradient through ATP synthase providing the energy needed to make ATP
Role of Oxygen
final electron acceptor
accepts electrons and forms bonds with hydrogen
by using up hydrogen the proton gradient is maintained so that chemiosmosis can continue
Adaptation
a change in structure so that something carries out its functions more efficiently
Mitochondrion
semi-autonomous organelle: can grow and reproduce itself but depends on the rest of the cell for resources and is otherwise part of the cellular system
70S ribosomes and a naked loop of DNA are found in the matrix
site of aerobic respiration
Outer Mitochondrial Membrane
separates the contents of the mitochondrion from the rest of the cell, creating a cellular compartment with ideal conditions for aerobic respiration
Intermembrane Space
proteins are pumped into this space by the electron transport chain, the space is small so concentration builds up quickly
Inner Mitochondrial Membrane
contains electron transport chains and ATP synthase
Matrix
contains enzymes for the Krebs cycle and the link reaction
Ribosome DNA
for expression of mitochondrial genes
Cristae
projections of the inner membrane which increase the surface area available for oxidative phosphorylation