8.1 Principles of Pharmacology

Question 1

Who can prescribe drugs?

Answer 1

Accredited authorized prescriber provider

Question 2

What form is used for Controlled Substances?

Answer 2

DD 1289

Question 3

For drugs taken PO, where is it absorbed and metabolized?

Answer 3

Liver

Question 4

What factors alter bioavailability?

Answer 4

• Liver metabolism
• the drug
• route of administration
• GI mucosa
• food
• solubility

Question 5

Define pharmacodynamics

Answer 5

Drug’s actions and effects within the body

Question 6

Define physical dependence

Answer 6

compulsive need to use a substance repeatedly to avoid mild to severe withdrawal sx

Question 7

Define Psychological dependence

Answer 7

compulsion to use a substance to obtain a pleasurable experience

Question 8

Define additive drug reaction

Answer 8

occurs when combined effect of 2 drugs is equal to sum of each drug given alone

Question 9

Define Synergism

Answer 9

drug interaction that occurs when drugs produce an effect that is greater than the sum of their separate actions

Question 10

Define antagonist drug reaction

Answer 10

when one drug interferes with the action of another, causing neutralization or a decrease in the effect of one drug

Question 11

What factors influence drug response?

Answer 11

• age
• weight
• gender
• disease
• route
• drug use
• pregnancy