8.1 origins of genetic variation Flashcards
the three origins of genetic variation
-meiosis - crossing over and independent assortment
- mutation
= random fertilisation
method of crossing over
1) homologous chromosomes line up next to each other (M1 prophase)
2) tangle at specific loci (chiasmata)
3) crossing over occurs and alleles are swapped
gene number and location is still the same but different allele combination
independent assortment
each pair of homologous chromosomes is arranged randomly ad lines up independently.
daughter cells contain a different arrangement of chromosomes.
gametes carry the same genes but with different combination of alleles.
how mutation cause genetic variation
by a point (gene) mutation
change in base sequences which changes polypeptide chain produces.
error occurs in DNA replication
change in structure of entire DNA by one different amino acid.
chromosome mutation
change in number or structure of chromosomes
error occurs in cell division
deletion mutation
a portion f chromosome is lost, involves the loss of genes, it is often lethal
duplication mutation
a portion of chromosome is doubled so gene sequence repeats
inversion mutation
a portion of chromosome is deleted then reattached in an inverted position. gene sequence is therefore reversed
translocation mutation
a portion of chromosome is deleted and rejoins at a different point in the same chromosome or a different chromosome
random fertalisation
fusion of two haploid gametes to form a diploid zygote.
meiosis results in two genetically distinct gametes, random fertalisation by egg and seprm will always generate different zygotes