8 Stages of Nervous System Develop

Question 1

What are the 8 stages of nervous system development?

Answer 1

Induction, proliferation, migration, aggregation, differentiation, synaptic connection, cell death, elimination and stabilization.

Question 2

Induction of neural plate by underlying ____ (~18 days gestation)
followed by neural tube formation (neurulation)

Answer 2

mesoderm

Question 3

Induction of neural plate by underlying mesoderm (~18 days gestation) is followed by _______

Answer 3

neural tube formation (neurulation)

Question 4

In nervous system development, there is localized

proliferation of ______ and _____

Answer 4

neural and glial progenitors

Question 5

Migration of immature cells from their birthplace to their ________
______ are important guides

Answer 5

Adult positions

Astrocytes

Question 6

Aggregation

of cells to form _____ parts of the brain

Answer 6

identifiable

Question 7

In nervous system develop, ____ undergo cell death

Answer 7

~50% of neurons

Question 8

Proliferation zones are located near ______

Answer 8

Ventricles

Question 9

Growthcones are?

Answer 9

dynamic extensions of growing

neurites seeking synaptic connectivity

Question 10

neural plate gives rise to ______

Answer 10

nervous system

Question 11

Neurulation is a folding process, which includes the transformation of the _____ into the _____

Answer 11

neural plate into the neural tube

Question 12

Neural crest migrates laterally from

Answer 12

neural plate

Question 13

Features of neural crest

Answer 13

autonomic and sensory ganglia
-
Schwann cells (myelin)
-
chromaffin cells in adrenal gland (adrenaline)
-
odontoblasts in teeth (dentin)

Question 14

Motor axons grow out from the neurons in the ____ plate

Answer 14

basal

Question 15

cells in _______ arise from the

neural crest

Answer 15

dorsal root ganglia

Question 16

cells in dorsal root ganglia arise from the

neural crest and extend ______

Answer 16

sensory fibers

Question 17

cells in dorsal root ganglia arise from the

neural crest and extend sensory fibers centrally to the region of the ____ plate, and ______

Answer 17

alar

peripherally

Question 18

Spina bifida (“split spine”) is a defective closure of the ______

Answer 18

vertebral column

Question 19

Failure of caudal neuropore

to close will result in ____

Answer 19

Spina bifida

Question 20

Spina bifida detectable with assay for ______; risk reduced with _______ (~0.4 mg daily) in diet.

Answer 20

alpha fetal protein

folic acid

Question 21

Spina bifida occulta is not ______ and may be associated with _______ or a

Answer 21

serious
vertebral abnormality
hairy patch

Question 22

Anencephaly results from failure of _____

neuropore to close

Answer 22

rostral