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Junior - Pharm II - 2 > 8 - Pregnancy > Flashcards

8 - Pregnancy Flashcards

1
Q

Nausea in pregnancy non pharm

A 
Ginger
Pyridoxinine (b-6)
Some other stuff that she will refuse to try
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2
Q

Persistent N/V in pregnancy options

A

1st gen histamine blockers
Dopamine antagonist
Serotonin antagonist
Glucocorticoids

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3
Q

What needs to be done when giving Histamine blockers to pregnant women?

A

D/C doxylamine (sleep aid) prior to starting

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4
Q

What are the preferred pregnancy 1st gen histamine blockers?

A

Meclazine

Dyphenhydramine

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5
Q

What are the preferred dopamine antagonist for n/v?

What are some problems with them?

A

Metoclopromide: tardive dyskenesia and dystonia

Promethazine: lower’s seizure threshold

Prochloperazine: case reports of malformations in infants

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6
Q

What are the serotonin antagonist preferred for pregnancy?

What side effects do they have?

A

Odnasetron: may cause septum defects, miscarriage, low birth wt

Granisetron: no pregnancy studies conducted

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7
Q

When are glucocorticoids safe to use in pregnancy for refractory n/v?

A

Only use short term and in the 2nd and 3rd trimester

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8
Q

What can pregnant women take for reflux?

A

Antacids
Sucralfate
H2 antagonist
PPI’s

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9
Q

What reflux med is never safe for pregnant women

A

Bismuth subsalicylate

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10
Q

Ranitidine and cimetidine in nursing?

A

They excrete in the milk but are considered safe to use

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11
Q

What is safe for constipation?

A

Basically everything

Fiber, 
decussate, 
Mg, 
lactulose, 
biscodyl
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12
Q

Diarrhea meds?

A 
Dietary changes (LOL)
Loperamide
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13
Q

Is loperamide really pregnancy safe?

A

Human studies are inconclusive, however animal studies have shown teratogenic effects

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14
Q

What is the preferred antipyretic?

A

Acetaminophen

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15
Q

What are the preferred cough and cold meds for preggo’s?

A

Diphenhydramine and chlorphreniramine are preferred

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16
Q

What about cough suppressants for pregnancy?

A

Opiates: neonatal withdrawl, abnormalities when used in 1st trimester

Guaifenisin: some risk of inguinal hernias

Benzonates: no data

17
Q

What is safe for rhinorrhea, sneezing and throat pain?

A

Saline spray

Cetylpryidinum (cepacol) is safe

18
Q

What should not be given for nose and throat stuff?

A

Decongestants: they reduce fetal blood flow and that is probably not the best thing for the new baby

19
Q

Beta-lactams in pregnancy?

A

Safe for All 3 trimesters

20
Q

Lincosalamides in pregnancy?

A

All 3 trimesters are good to go

21
Q

Nitrofurantoin?

A

Antibiotic for urinary tract infection

Safe for 2nd and 3rd trimester

22
Q

What abx should be avoided in pregnancy?

A

Sulfonamides: trimethoprim/sulfamethozazole (bactrum)

Fluoroquinolones: ciprofloxacin, levofolaxacin

Tetracyclines: tetracycline, doxycycline

23
Q

Nitromidazoles: Flagyl (metronidazole)?

A

ABX: Safe in 2nd and 3rd trimester

24
Q

What anti-fungals are pregnancy safe?

A

Fluconazole
Clotrimazole
Miconazole
Nystatin

25
Q

What anti-fungals are not safe for pregnancy?

A

Butoconazole
Miconazole
Ticonazole

Never use these

26
Q

Can i give antivirals to pregnant women

A

Sure, the vir’s are good to go

27
Q

What about high potency steroids?

A

Sorry, you cannot have those

28
Q

Tretinoin (retin-A)?

A

No that will make a very unhealthy baby

29
Q

What is the primary and secondary drugs for chronic HTN in pregnancy (preeclampsia)
Urgent/emergent (3 drugs)

A

Chronic:

1: Methyldopa
2: labetalol

Urgent:

  1. Hydralazine
  2. Labetalol
  3. Nifedipine
30
Q

What is the DOC for the treatment of eclampsia?

A

Magnesium sulfate IV

31
Q

Pregnancy and diuretics?

A

If a woman is on diuretics they are safe to continue however do not start them during gestation

32
Q

What about cardiac meds?

A

B-blockers : intrauterine fetal growth retardation

ACEI and ARB’s: teratogenic

33
Q

How is gestational DM (GDM) treated?

A

Insulin is the preferred medication

Glyburide and metformin are category B however they lack long term safety data

34
Q

What should every woman of reproductive age take?

A

Folic acid

35
Q

What are the 3 types of anemia commonly seen in preggo’s?

A

Iron, folate and b12

36
Q

Iron recommendation in pregnancy?

A

27mg/day ought to do it

37
Q

When snoop dogg is 60 how old will he be in dog years?

A

420

Junior - Pharm II - 2 (3 decks)

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